[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600970":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":12,"responsibleParty":37,"collaborators":12,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":12,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":63,"whyStopped":12,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":12},{"fullName":5,"class":6},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"control group","NO_INTERVENTION","sedation with remifentanil and propofol",null,{"label":14,"type":15,"description":16,"interventionNames":17},"RVH group","EXPERIMENTAL","RVH session + sedation with remifentanil and propofol",[18],"Other: virtual reality hypnosis device",[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":12},"virtual reality hypnosis device","VRH group, in which patients will receive conventional sedation (remifentanil 0.1 mcg\u002Fkg\u002Fmin and propofol 0.5 mg\u002Fkg if necessary) and a Virtual Reality headset with an environment chosen by the patient and hypnosis support with suggestions to reduce their anxiety.",[14],[25],{"name":26,"affiliation":5,"role":27},"Fabienne Roelants, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":12,"email":32},"CONTACT","+3227641821","fabienne.roelants@saintluc.uclouvain.be",{"name":34,"role":30,"phone":35,"phoneExt":12,"email":36},"Céline Pirard, MD, PhD","+3227644115","celine.pirard@saintluc.uclouvain.be",{"type":38,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100600970","virtual-reality-hypnosis-as-sedation-during-oocyte-retrieval-effect-on-propofol-consumption-100600970",false,"NCT07104409","Virtual Reality Hypnosis as Sedation During Oocyte Retrieval: Effect on Propofol Consumption","Virtual Reality Hypnosis as Sedation During Oocyte Retrieval: Effect on Propofol Consumption: a Randomized Study (VRH-IVF)","VRH-IVF","Inclusion Criteria:\n\n* egg retrieval as part of their IVF at the Cliniques universitaires Saint-Luc,\n* to be French-speaking,\n* simple IVF or ICSI IVF\n* 18-42 yrs\n\nExclusion Criteria:\n\n* morbid obesity\n* blindness and\u002For deafness\n* history contraindicating the use of anti-inflammatory drugs\n* long-term psychotherapeutic treatment or taking psychotropic medications.","FEMALE","18 Years","42 Years",{"count":51,"type":52},72,"ESTIMATED","INTERVENTIONAL",[55],"NA","An egg retrieval is performed during an IVF course. This painful procedure is performed using sedation to ensure patient comfort. A combination of sedative and analgesic medications combined with local anesthesia (paracervical block) is used. Propofol, the intravenous anesthetic of choice (rapid-acting and short-acting), and remifentanil (an ultra-short-acting opioid analgesic) are generally combined. The potential impact of these agents used for egg retrieval on egg fertilization and embryo quality is of interest. Indeed, certain drugs such as propofol could accumulate in the follicular fluid. The few studies conducted to date show contradictory results. While a harmful effect appears to be reported in experimental studies on mice, this effect is uncertain in clinical studies. Given this uncertainty, any method aimed at reducing propofol consumption in this context may be of interest. Virtual reality hypnosis (VRH) is a digital tool that has already been shown to be effective in reducing preoperative anxiety during oocyte retrieval. Furthermore, VRH has also demonstrated analgesic effects.\n\nThe primary objective of this study is to compare VRH with a control group (usual sedation) on propofol consumption during oocyte retrieval.\n\nSecondary objectives are to compare preoperative anxiety, APAIS score, catastrophizing score, remifentanil consumption, intra- and\u002For post-operative nausea and vomiting, post-procedural analgesic consumption, time perception during the procedure, fertilization parameters, and pregnancy rate at 12 weeks. The degrees of absorption, dissociation, immersion, and presence for the VRH group will also be noted.",[58],"Oocyte Retrieval for IVF",[60,61,62],"virtual reality","hypnosis","oocyte retrieval","NOT_YET_RECRUITING","2025-08-05",{"date":66,"type":67},"2025-08-11","ACTUAL",{"date":69,"type":52},"2025-09-01",{"date":71,"type":52},"2027-02-01",{"name":5,"class":6}]