[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604118":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":12,"locations":12,"responsibleParty":24,"collaborators":12,"id":26,"slug":27,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":31,"acronym":12,"eligibilityCriteria":32,"healthyVolunteers":28,"sex":33,"minAge":34,"maxAge":12,"enrollmentInfo":35,"targetDuration":12,"studyType":38,"phases":39,"briefSummary":41,"conditions":42,"keywords":12,"overallStatus":49,"whyStopped":12,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":12},{"fullName":5,"class":6},"Halic University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","Participants in this group will receive standard clinical care during hematopoietic stem cell transplantation (HSCT) without any additional intervention. They will not be exposed to any virtual reality content during the procedure. This group serves as the comparator to evaluate the effects of the VR intervention.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Experimental group","EXPERIMENTAL","Participants in this group will receive standard clinical care during hematopoietic stem cell transplantation (HSCT) along with a 15-minute virtual reality (VR) intervention. The VR intervention involves viewing a nature-themed immersive video through a Meta Quest 3 headset. Patients will select one of five pre-approved videos created or curated by the research team based on Attention Restoration Theory (ART). The VR session will begin one minute before the stem cell infusion and end at the 15th minute of the procedure. The intervention is administered under the supervision of the researcher.",[18],"Other: Virtual Reality Intervention",[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":12},"Virtual Reality Intervention","This intervention is distinguished by its integration of a structured, nurse-led virtual reality (VR) protocol specifically designed for symptom management during hematopoietic stem cell transplantation (HSCT). Unlike general VR distraction methods used in oncology, this intervention employs video content created by the research team in accordance with Attention Restoration Theory (ART), offering five preselected nature-themed options tailored to patient preferences. Prior to the procedure, eligible patients are introduced to the intervention one day in advance and given the opportunity to trial the VR equipment, ask questions, and select their preferred video. During the infusion, VR is initiated exactly one minute before the stem cell procedure and ends at the 15th minute, as recommended by the literature. Symptom assessments are conducted immediately before and after the intervention using validated tools, including the Distress Thermometer, State Anxiety Inventory, and the Edmonto",[14],{"type":25,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100604118","virtual-reality-intervention-for-symptom-management-in-stem-cell-transplantation-100604118",false,"NCT07145359","Virtual Reality Intervention for Symptom Management in Stem Cell Transplantation","Development and Evaluation of A Virtual Reality Intervention for Symptoms Management During Hematopoietic Stem Cell Transplantation","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Able to speak and understand Turkish\n* Scheduled to undergo allogeneic hematopoietic stem cell transplantation (HSCT)\n* Receiving stem cell products collected from peripheral blood\n* Voluntarily agree to participate in the study and provide informed consent\n\nExclusion Criteria:\n\n* Undergoing autologous hematopoietic stem cell transplantation\n* Receiving stem cell products collected from bone marrow\n* Diagnosed with medical or psychiatric comorbidities that could interfere with participation, as reported by the healthcare team\n* Presenting infection symptoms (e.g., respiratory, gastrointestinal) that may contaminate study equipment, as identified by the healthcare team\n* Having visual, auditory, verbal, or cognitive impairments that may prevent interaction with the VR equipment\n* Previously received any form of hematopoietic stem cell transplantation","ALL","18 Years",{"count":36,"type":37},30,"ESTIMATED","INTERVENTIONAL",[40],"NA","The goal of this clinical trial is to evaluate whether a virtual reality (VR) intervention based on the Symptom Management Model can reduce physical and psychosocial symptoms during hematopoietic stem cell transplantation (HSCT) in adult patients undergoing allogeneic transplantation.\n\nThe main questions it aims to answer are:\n\nDoes the VR intervention reduce distress levels during HSCT?\n\nDoes the VR intervention decrease state anxiety and symptom severity compared to standard care?\n\nDoes the VR intervention positively affect physiological outcomes and engraftment times?\n\nResearchers will compare a group receiving standard clinical care plus a VR nature-themed video during HSCT to a group receiving standard care only to see if the VR intervention improves symptom management outcomes.\n\nParticipants will:\n\nBe randomly assigned to either the intervention or control group.\n\nIn the intervention group:\n\nWatch a 15-minute nature-themed VR video during stem cell infusion using Meta Quest 3.\n\nThe video content will be specifically created by the research team based on the principles of Attention Restoration Theory (ART).\n\nIn both groups:\n\nComplete pre- and post-intervention assessments including:\n\nDistress Thermometer\n\nState-Trait Anxiety Inventory\n\nEdmonton Symptom Assessment Scale\n\nPhysiological measures (vital signs)\n\nEngraftment tracking\n\nSatisfaction and open-ended feedback forms",[43,44,45,46,47,48],"Cancer and \u002F or Hematological Malignancy","Hematopoetic Stem Cell Transplantation","Nursing Interventions","Symptom Management","Virtual Reality","ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION","NOT_YET_RECRUITING","2025-08-21",{"date":52,"type":53},"2025-08-28","ACTUAL",{"date":55,"type":37},"2025-09-10",{"date":57,"type":37},"2026-09-10",{"name":5,"class":6}]