[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612529":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":20,"locations":20,"responsibleParty":21,"collaborators":20,"id":25,"slug":26,"hasResults":27,"nctId":28,"briefTitle":29,"officialTitle":30,"acronym":20,"eligibilityCriteria":31,"healthyVolunteers":27,"sex":32,"minAge":33,"maxAge":20,"enrollmentInfo":34,"targetDuration":20,"studyType":37,"phases":38,"briefSummary":40,"conditions":41,"keywords":43,"overallStatus":51,"whyStopped":20,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":20},{"fullName":5,"class":6},"Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"3-Phase Arm","EXPERIMENTAL","Using repeated measurements over time, in three phases, i.e. an observation phase A, an intervention phase B and a post-intervention follow-up phase C, each participant will be his or her own control.\n\nPhase A : consists of an observational period without intervention, aimed at establishing a baseline and gaining a clearer understanding of the individual characteristics and patterns of neuropathic pain in each participant.\n\nPhase B : The intervention will be provided during Phase B. The intervention consists of starting neuromodulation 5min with tDCS alone, then adding virtual walking (virtual reality + corresponding somatosensory stimulation, via muscle vibration in the lower limbs) for the last 15min Phase C: follow up until 6monts post the end of the intervention.",[13],"Device: Transcranial Direct Current Stimulation (tDCS) combined with virtual reality and muscle vibration",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Transcranial Direct Current Stimulation (tDCS) combined with virtual reality and muscle vibration","tDCS will be delivered over the primary motor cortex (M1) to maximize the analgesic effect. The cathode will be positioned over the suborbital region, and the anode over M1 (position C3 or C4 of the international 10-20 system). A 2 mA direct current will be applied.\n\nParticipants will observe, through virtual reality goggles (HTC Vive), an avatar walking from a first-person perspective, synchronized with the vibration pattern. Twelve vibrators will be placed transversely and bilaterally over the tendons of the main flexors and extensors of the lower limbs.\n\nThe pattern used to trigger the vibrators is based on the natural sequence of gait movement. Muscle vibration induces a perception of movement in the direction of muscle elongation. The target frequency of the vibrators will be 80 Hz.\n\nThe session will begin with 5 minutes of tDCS alone, and then for the last 15minutes the investigators will combine tDCS, virtual reality and muscle vibration.",[9],null,{"type":22,"investigatorFullName":23,"investigatorTitle":24,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Cyril Duclos","Professor","100612529","virtual-walking-and-neuromulation-to-reduce-neuropathic-pain-after-a-spinal-cord-injury-100612529",false,"NCT07254767","Virtual Walking and Neuromulation to Reduce Neuropathic Pain After a Spinal Cord Injury","Combination of Visuo-proprioceptive Virtual Walking and Neuromodulation to Reduce Neuropathic Pain in Individuals With Spinal Cord Injury","Inclusion Criteria:\n\n* over 18 years old\n* a score of ≥ 4\u002F10 on the Douleur Neuropathique en 4 Questions (DN4)\n* classified AIS A to D\n* neuropathic pain with an intensity of ≥ 4\u002F10 on the simple numerical rating scale (This threshold is often chosen to better observe a potential analgesic effect)\n\nExclusion Criteria: The main exclusion criteria are contraindications to tDCS and virtual reality\n\n* pregnancy,\n* epilepsy,\n* cancer,\n* pacemaker,\n* metallic implants in the brain or eyes,\n* uncontrolled severe headaches,\n* uncontrolled psychotic disorders,\n* open scalp wounds,\n* severe visual impairments. If participants have suffered a major traumatic brain injury with significant cognitive impairments, inclusion in the study will depend on the medical team's judgment. Finally, participants with allodynia in the areas where vibrators will be placed will not be included in the protocol","ALL","18 Years",{"count":35,"type":36},10,"ESTIMATED","INTERVENTIONAL",[39],"NA","The goal of this single-subject design is to evaluate an intervention combining neuromodulation, virtual reality, and muscle vibration to reduce neuropathic pain in individuals following a spinal cord injury.\n\nThe investigators aim to quantify the effects of the intervention on the intensity and characteristics of neuropathic pain, as well as its impact on daily functioning in individuals undergoing SCI rehabilitation. Additionally, the investigators seek to gain a better understanding of participants' experiences with the intervention by exploring effects not captured by standardized questionnaires, and by examining the role and meaning of the intervention in their management and experience of pain.\n\nFinally, the investigators aim to assess the feasibility and clinical relevance of implementing this intervention in a rehabilitation setting.\n\nAll participants living with neuropathic pain following a spinal cord injury will take part in ten intervention sessions. They will also be invited to complete standardized questionnaires and participate in a semi-structured interview. In addition, their clinicians will be invited to participate in a focus group.",[42],"Neuropathic Pain",[44,45,46,47,48,49,50],"neuropathic pain","spinal cord injury","mixed methods","single subject design","tDCS","virtual reality","muscle vibration","NOT_YET_RECRUITING","2025-11-20",{"date":54,"type":55},"2025-11-28","ACTUAL",{"date":57,"type":36},"2025-12-01",{"date":59,"type":36},"2027-09",{"name":5,"class":6}]