[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601043":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":27,"centralContacts":37,"locations":47,"responsibleParty":68,"collaborators":27,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":27,"enrollmentInfo":80,"targetDuration":27,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":27,"overallStatus":50,"whyStopped":27,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Georgetown University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"tRNS with perceptual learning-based training","EXPERIMENTAL","Each 2-day session consists of up to three 18-minute transcranial random noise stimulation (tRNS) paired with perceptual learning-based training.",[13,14],"Device: transcranial random noise stimulation (tRNS)","Behavioral: Perceptual learning-based training",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham with perceptual learning-based training","SHAM_COMPARATOR","Each 2-day session consists of up to three 18-minute sham stimulation paired with perceptual learning-based training.",[20,14],"Device: Sham Stimulation",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","transcranial random noise stimulation (tRNS)","Stimulation location: bilateral human middle temporal complex (hMT+). Stimulation parameters: 1 mA current intensity, with a frequency range of 101-640 Hz.",[9],null,{"type":23,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"Sham Stimulation","Stimulation location: bilateral human middle temporal complex (hMT+). Stimulation parameters: Ramp up stimulation at 1mA with a frequency range of 101-640Hz for the first 30 seconds followed by no current for the remainder of the duration.",[16],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":27},"BEHAVIORAL","Perceptual learning-based training","A motion discrimination task, judging the global direction of moving dot stimuli with two different coherence levels.",[16,9],[38,43],{"name":39,"role":40,"phone":41,"phoneExt":27,"email":42},"Tina Liu, PhD","CONTACT","2027849920","tina.liu@georgetown.edu",{"name":44,"role":40,"phone":45,"phoneExt":27,"email":46},"Kyungji Moon, MS","2027849949","vpplab@georgetown.edu",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Georgetown University Medical Center","RECRUITING","Washington D.C.","District of Columbia","20057","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-77.03637,38.89511,{"lat":60,"lon":59},[63,66],{"name":64,"role":40,"phone":65,"phoneExt":27,"email":46},"Visual Perception and Plasticity Lab","202-784-9949",{"name":39,"role":67,"phone":27,"phoneExt":27,"email":27},"PRINCIPAL_INVESTIGATOR",{"type":69,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100601043","visual-plasticity-following-brain-lesions-100601043",false,"NCT07105358","Visual Plasticity Following Brain Lesions","Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training","VIBRANT","A. Stroke, brain tumor, or traumatic brain injury patients\n\nInclusion Criteria:\n\n1. At least 18 years of age.\n2. Capable of providing informed consent and complying with study procedures.\n3. Unilateral or bilateral focal brain damage causing loss of vision.\n4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.\n\nExclusion Criteria:\n\n1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.\n2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.\n3. Vision loss resulting from ocular disease or disorder.\n\nB. Healthy volunteers (age-matched controls):\n\nInclusion Criteria:\n\n1. At least 18 years of age.\n2. Capable of providing informed consent and complying with study procedures.\n\nExclusion Criteria:\n\n1. Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results.\n2. Previous head injury.\n3. Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.","ALL","18 Years",{"count":81,"type":82},30,"ESTIMATED","INTERVENTIONAL",[85],"NA","The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.",[88,89,90,91,92,93,94,95],"Visual Field Defect","Stroke","Hemianopia","Quadrantanopia","Cortical Blindness","Brain Tumor","Traumatic Brain Injury","Visual Field Defect, Peripheral","2025-07-29",{"date":98,"type":99},"2025-08-05","ACTUAL",{"date":101,"type":99},"2025-07-17",{"date":103,"type":82},"2028-06-30",{"name":5,"class":6},1]