[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100376273":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":11,"responsibleParty":34,"collaborators":7,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":7,"eligibilityCriteria":42,"healthyVolunteers":43,"sex":44,"minAge":45,"maxAge":7,"enrollmentInfo":46,"targetDuration":7,"studyType":49,"phases":7,"briefSummary":50,"conditions":51,"keywords":53,"overallStatus":13,"whyStopped":7,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"University of Surrey","OTHER",null,[9],{"type":6,"name":10,"description":10,"armGroupLabels":7,"otherNames":7},"N\u002FA - no intervention. Observational study.",[12],{"facility":5,"status":13,"city":14,"state":7,"zip":15,"country":16,"countryCode":17,"cosmosGeoPoint":18,"geoPoint":23,"contacts":24},"RECRUITING","Guildford","GU27XH","United Kingdom","UK",{"type":19,"coordinates":20},"Point",[21,22],-0.57427,51.23536,{"lat":22,"lon":21},[25,30],{"name":26,"role":27,"phone":28,"phoneExt":7,"email":29},"Rebecca Vearing, PhD","CONTACT","01483689222","rv00158@surrey.ac.uk",{"name":31,"role":27,"phone":32,"phoneExt":7,"email":33},"Susan Lanham-New","01483686476","s.lanham-new@surrey.ac.uk",{"type":35,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100376273","vitamin-d-and-health-status-of-british-african-caribbean-women-100376273",false,"NCT04179370","Vitamin D and Health Status of British African-Caribbean Women","The Relationship Between Sun Exposure, Diet, Lifestyle and Bone on Vitamin D Status (25OHD) in British African-Caribbean Women Living in Southern United Kingdom","Inclusion Criteria:\n\n* Women\n* British African-Caribbean Self-reported Having African ancestral origin and migrated via the Caribbean islands, or having at least one parent with African ancestral origin that migrated via the Caribbean\n* Living in England for \\>2 months\n* Aged 18-35 or \\>55 years\n* No significant health issues\n* Pre-menopausal (regular menstrual periods) or Post-menopausal (menstrual periods stopped for longer than 12 consecutive months)\n* BMI 18-30kg\u002Fm2\n\nExclusion Criteria:\n\n* Women in perimenopause or menopause\n* Pregnant or planning pregnancy during study period\n* Hypercalcaemia (\\>2.5mmol\u002FL) - assessed and excluded at baseline\n* Currently receiving treatment for medical conditions that are likely to affect vitamin D metabolism (osteoporosis, hormone replacement therapy, anti-estrogens treatment, antiepileptic drugs and breast cancer treatment)\n* Regular use of sun beds\n* Having a sun holiday one month prior to commencing study or plans for a sun holiday for more than 4 weeks within the study period\n* Women who take vitamin D or calcium supplements (or multivitamin supplements that contain these vitamins) - If potential participant agrees to stop supplement use to join the study, a wash-out period of 8 weeks prior to commencing the study is acceptable\n* Living in England for less than 2 months",true,"FEMALE","18 Years",{"count":47,"type":48},100,"ESTIMATED","OBSERVATIONAL","Vitamin D deficiency remains a global public health issue (Wilson 2017). In the United Kingdom (UK). There is a lack of research looking at vitamin D status of the British African-Caribbean population. This population is particularly at risk to vitamin D deficiency due to possessing a skin type which hinders the production of vitamin D in the skin. Further, due to the geographical location of the UK, there is reduced ability to produce vitamin D due to the low sun exposure (Libon 2013 ). Our main source of vitamin D is through skin exposure to the sun. In the UK, the UV radiation is only strong enough in April-September (Wilson 2017) for the production of vitamin D to occur. In winter months, vitamin D needs to be consumed in food or supplement form. Vitamin D is essential for healthy bones and is associated with reduced risk of certain cancers and immune disorders (Wilson 2017). There is strong epidemiological evidence linking low vitamin D status with diabetes, cardiovascular disease, osteoporosis, osteoarthritis and some cancers (NatCen 2018).\n\nThis observational study will aim to determine the vitamin D status of British Afro-Caribbean women, as well as determine the effects of sun exposure, dietary vitamin D intake, muscular strength, lifestyle and anthropometrical (height, weight etc.) factors have on vitamin D status. The study will be conducted at the University of Surrey. The study will take place in Autumn and winter 2019\u002F2020 and a repeat study in Spring 2020. Each participant will require two visits to the university, each session will take approximately 2 hours. The study is funded by the University of Surrey. The findings of this study may lead to strategies for improving vitamin D status in this population, as well as improving guidelines to assist darker-skinned people regarding sunlight exposure in high latitudes.",[52],"Vitamin D Deficiency",[54,55],"vitamin D OR 25(OH)D","African-Caribbean OR Afro-Caribbean","2024-12-11",{"date":58,"type":59},"2024-12-16","ACTUAL",{"date":61,"type":59},"2020-02-07",{"date":63,"type":48},"2025-03-31",{"name":5,"class":6},1]