[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100263177":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":33,"locations":38,"responsibleParty":58,"collaborators":60,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":10,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":10,"studyType":75,"phases":10,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Cornell University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D dynamics- pregnant",null,"Pregnant women recruited to measure Vitamin D dynamics during pregnancy.",[13],"Other: Vitamin D dynamics-pregnant",{"label":15,"type":10,"description":16,"interventionNames":17},"Vitamin D dynamics-nonpregnant","Non-pregnant women recruited to measure Vitamin D dynamics.",[18],"Other: Vitamin D dynamics-nonpregnant",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Vitamin D dynamics-pregnant","tracer dose of deuterated vitamin D3",[9],{"type":6,"name":15,"description":22,"armGroupLabels":25,"otherNames":10},[15],[27,30],{"name":28,"affiliation":5,"role":29},"Kimberly O. O'Brien, PhD","PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":32,"role":29},"Eva Pressman, MD","University of Rochester",[34],{"name":28,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","607-255-3743","koo4@cornell.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"University of Rochester, 518 Hylan Building","RECRUITING","Rochester","New York","14627","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-77.61556,43.15478,{"lat":51,"lon":50},[54],{"name":55,"role":35,"phone":56,"phoneExt":10,"email":57},"Brenda Kavanaugh","585-275-1504","bkavanaugh@orpa.rochester.edu",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[61],{"name":32,"class":6},"100263177","vitamin-d-dynamics-in-women-100263177",false,"NCT02705287","Vitamin D Dynamics in Women","Vitamin D Dynamics in Pregnant Women and Non-Pregnant Women of Reproductive Age","Inclusion Criteria (Non-pregnant and pregnant participants participants):\n\n* Self-reported White and Black women\n* Age 20-39\n* Body mass index (BMI) 1or pre-pregnancy BMI (If currently pregnant) either 18.5-24.9 kg\u002Fm2 or greater than or equal to 30 kg\u002Fm2\n\nInclusion Criteria (Additional criteria for pregnant participants):\n\n* Singleton pregnancy\n* Recruited in first trimester, second trimester, or third trimester\n* No pregnancy complications\n\nExclusion Criteria (Non-pregnant and pregnant participants):\n\n* BMI or pre-pregnancy BMI \\\u003C18.5 kg\u002Fm2\n* Human immunodeficiency virus (HIV) infection\n* Diagnosed eating disorder\n* Malabsorption disease\n* Diabetes\n* Elevated diastolic blood pressure (\\>110 mm\u002FHg)\n* Steroid use\n* Substance abuse history\n* Current use of medications known to influence vitamin D or calcium homeostasis\n* Plans to travel to lower latitude during the 20-day study period\n* Plans to become pregnant during the study period (non-pregnant only)\n* Refuses to discontinue tanning bed use during study period\n* Refuses to discontinue vitamin or mineral supplement use during study period (non-pregnant only)\n\nExclusion Criteria (Additional criteria for pregnant participants):\n\n* Gestational diabetes\n* Pregnancy hypertension","FEMALE","20 Years","39 Years",{"count":73,"type":74},160,"ESTIMATED","OBSERVATIONAL","The goal of this project is to utilize stable isotopically labeled vitamin D3 and state of the art mass spectrometric methodology to assess vitamin D dynamics during pregnancy in relation to relation to obesity and vitamin D binding protein genotype. At the conclusion of this study, the investigators will have obtained novel information on the absorption and utilization of vitamin D in women and the degree to which vitamin D utilization during pregnancy is impacted by genetic ancestry, vitamin D binding protein concentration and genotype and by excess adiposity. The long-term goal is to better understand the unique metabolism of vitamin D during pregnancy.",[78],"Pregnancy",[80,81,82],"vitamin D","half life","kinetics","2026-03-27",{"date":85,"type":86},"2026-04-01","ACTUAL",{"date":88,"type":86},"2024-10-28",{"date":90,"type":74},"2029-05",{"name":5,"class":6},1]