[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643250":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":47,"responsibleParty":72,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":29,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":29,"maxAge":87,"enrollmentInfo":88,"targetDuration":29,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":29,"overallStatus":50,"whyStopped":29,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"The Methodist Hospital Research Institute","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"VR intervention: VR-based cognitive stimulation games","EXPERIMENTAL","Participants will engage in interactive, VR-based cognitive stimulation games.",[13],"Other: Virtual Reality Software",{"label":15,"type":10,"description":16,"interventionNames":17},"VR Control: watching a movie in VR","Participants will watch a non-interactive VR movie experience consisting of educational material.",[18],"Other: Virtual Reality movies",{"label":20,"type":10,"description":21,"interventionNames":22},"Nurse control: standard-of-care nurse-led reality orientation","Participants will receive standard-of-care, nurse-led reality orientation therapy.",[23],"Other: Nurse led control arm",[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Virtual Reality Software","The ReCognition virtual reality (VR) software is delivered via an Oculus Quest 2 device. This three-dimensional simulated software was designed to improve attention and executive functions. The VR session will occur once per day for 20 minutes.",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Virtual Reality movies","This virtual reality software is delivered via an Oculus Quest 2 device. The Oculus Quest 2 device will be used to watch an educational movie. The VR session will occur once per day for 20 minutes.",[15],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Nurse led control arm","Reality orientation therapy focused on time, place, and person, administered twice daily, typically at the beginning and end of nursing shifts.",[20],[39],{"name":40,"affiliation":5,"role":41},"Hina Faisal, MD","PRINCIPAL_INVESTIGATOR",[43],{"name":40,"role":44,"phone":45,"phoneExt":29,"email":46},"CONTACT","346-356-1400","hfaisal@houstonmethodist.org",[48,65],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Houston Methodist Hospital","RECRUITING","Houston","Texas","77030","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-95.36327,29.76328,{"lat":60,"lon":59},[63],{"name":40,"role":44,"phone":64,"phoneExt":29,"email":46},"713-448-0343",{"facility":66,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":67,"geoPoint":69,"contacts":70},"Houston Methodist Research Insititute",{"type":57,"coordinates":68},[59,60],{"lat":60,"lon":59},[71],{"name":40,"role":41,"phone":29,"phoneExt":29,"email":29},{"type":41,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Hina Faisal","Associate Professor of Surgery, Anesthesia & Critical Care",[76],{"name":77,"class":78},"National Institute on Aging (NIA)","NIH","100643250","vr-based-cognitive-stimulation-games-for-delirium-prevention-100643250",false,"NCT07641153","VR-Based Cognitive Stimulation Games for Delirium Prevention","Virtual Reality-Based Cognitive Stimulation Games for Enhancing Attention and Preventing Delirium in Older Surgical Patients With Cognitive Impairment","Inclusion Criteria:\n\n* Men and women ≥65 years of age\n* Have a pre-existing diagnosis of cognitive impairment (Montreal Cognitive Assessment Score of 15-24)\n* Elective or emergency major surgery with the expectation of admission to the Intensive Care Unit following the surgery for three days following surgery\n\nExclusion Criteria:\n\n* Pre-existing Intubation and invasive ventilation;\n* history of severe mental illness;\n* admission for a drug overdose;\n* severe vertigo;\n* history of severe postoperative nausea and vomiting;\n* hearing and visual impairment;\n* preexisting severe dementia (Montreal Cognitive Assessment Score \\\u003C 15; and\n* active delirium at the time of screening for eligibility criteria.\n* Active suicidal ideation or behavior Screen failure after surgery\n* Prolonged intubation after surgery (more than 24 hours)","ALL","65 Years",{"count":89,"type":90},90,"ESTIMATED","INTERVENTIONAL",[93],"NA","This trial aims to evaluate the feasibility, safety, and acceptability of a virtual reality (VR)-based cognitive stimulation game to reduce postoperative delirium among older surgical patients at high risk due to pre-existing cognitive impairment.",[96,97,98],"Surgery","Delirium - Postoperative","Delirium","2026-06-08",{"date":101,"type":102},"2026-06-11","ACTUAL",{"date":104,"type":102},"2026-04-24",{"date":106,"type":90},"2029-05-01",{"name":5,"class":6},2]