[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595680":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":66,"collaborators":70,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":74,"sex":80,"minAge":81,"maxAge":26,"enrollmentInfo":82,"targetDuration":26,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":94,"overallStatus":97,"whyStopped":26,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Sahlgrenska University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Training intervention arm","EXPERIMENTAL","Targeted supervised training program of specific training of levator, abdominal, quadriceps (all portions), and gluteal muscles as well as endurance training.",[13],"Procedure: Targeted leaderled training program",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","ACTIVE_COMPARATOR","Information of training in accordance with WHO recommendations of 30 min aerobic physical activity five times per week (150 min per week) plus strength sessions twice weekly.",[19],"Procedure: Control arm with WHO recommendation on physical activity",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Targeted leaderled training program","Training program:\n\nAfter inclusion and consent the patients are instructed through an online group training program consisting of specific training of levator, abdominal, quadriceps (all portions), and gluteal muscles as well as endurance training. They are given information about WHO recommendations about physical activity. The patients are asked to sign up for two specific training occasions per week where no group will be larger than 10 patients. Group based exercise sessions consist of 45-minute supervised online zoom exercise sessions. Apart from the supervised sessions patients are encouraged to perform one functional training session, unsupervised, as well as follow the WHO recommendation for aerobic exercise",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Control arm with WHO recommendation on physical activity","Training will be in accordance with WHO recommendations of 30 min aerobic physical activity five times per week (150 min per week) plus strength sessions twice weekly. The patients will be individually adviced on how to perform the training at inclusion in the trial. This is considered standard care and will not include any on-line supervision, but will include a coaching\u002Freminder by a phone call from a research nurse\u002Fshort message service (by choice of the patient) at regular intervals before and after surgery",[15],[32],{"name":33,"affiliation":34,"role":35},"Charlotta E Larsson, MD, PhD","Department of Surgery, SSORG - Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden and Region Västra Götaland, Sahlgrenska University Hospital Östra","PRINCIPAL_INVESTIGATOR",[37,42],{"name":33,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","+ 46706067980","0707232986","charlotta.e.larsson@vgregion.se",{"name":43,"role":38,"phone":26,"phoneExt":26,"email":44},"Lina Björklund Sand, MD","lina.bjorklund.sand@vgregion.se",[46],{"facility":47,"status":26,"city":48,"state":26,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Department of Surgery, SSORG - Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 416 85 Gothenburg, Sweden.","Gothenburg","416 85","Sweden","SE",{"type":53,"coordinates":54},"Point",[55,56],11.96679,57.70716,{"lat":56,"lon":55},[59,62,63],{"name":60,"role":38,"phone":26,"phoneExt":26,"email":61},"Carolina Ehrencrona","carolina.ehrencrona@gu.se",{"name":33,"role":38,"phone":26,"phoneExt":26,"email":41},{"name":64,"role":65,"phone":26,"phoneExt":26,"email":26},"Eva Haglind, MD, Professor","SUB_INVESTIGATOR",{"type":35,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":69,"oldNameTitle":26,"oldOrganization":26},"Charlotta Larsson, MD PhD","MD PhD","Göteborg University",[71],{"name":69,"class":6},"100595680","walking-and-sitting-difficulties-after-rectal-cancer-surgery-100595680",false,"NCT07035600","Walking and Sitting Difficulties After Rectal Cancer Surgery","WASA - Walking and Sitting Difficulties After APE","WASA","Inclusion Criteria:\n\n* Patients with rectal cancer to be treated with\u002Fwithout neoadjuvant (chemo)radiation and abdominoperineal excision with or without mesh (APE\u002FELAPE) Informed consent Able to read and understand Swedish or Danish\n\nExclusion Criteria:\n\n* Patients with rectal cancer to be operated by extended abdominoperineal excision (ELAPE) requiring musculocutaneous or muscular flaps to be operated by Hartmann's procedure to be operated by anterior resection (low or high) participation in other randomized trials in conflict with the protocol and endpoints of the WASA trial Not understanding Swedish or Danish Patients reporting habit of physical activity exceeding the WHO-recommendations (150 min + two strength sessions) at baseline.","ALL","18 Years",{"count":83,"type":84},300,"ESTIMATED","INTERVENTIONAL",[87],"NA","Earlier studies have shown that many patients (up to 30%) who have had a major surgery for rectal cancer, called a rectum amputation (where the entire rectum and anus are removed and the person gets a permanent stoma), still have trouble sitting and walking three years after the surgery. These problems are then seen as long-term or chronic.\n\nWASA is a randomized multicenter international study that will test a way to reduce these problems. It will start in fall 2025 and go on for 3.5 years. About 300 patients will take part.\n\nThe patients will be randomly divided into two groups. One group will get guided online training twice a week, specially made for their needs. The other group will get information about the World Health Organization's (WHO) general advice on physical activity.\n\nThe idea is that special training during the first year after surgery will reduce problems with walking and sitting. If the hypothesis can be confirmed, it could lead to an easy and low-cost way to help many rectal cancer patients feel and function better.",[90,91,92,93],"Rectal Cancer Patients","Rectal Cancer Surgery","Rectal Cancer, Radiotherapy","Rectal Cancer",[95,96],"Rectal cancer","Rectal cancer complications","NOT_YET_RECRUITING","2025-06-16",{"date":100,"type":101},"2025-06-25","ACTUAL",{"date":103,"type":84},"2025-09-15",{"date":105,"type":84},"2031-04-01",{"name":5,"class":6},1]