[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610356":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":58,"collaborators":11,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":11,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":87,"whyStopped":11,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Robot assisted gait training combined with Transcutaneous spinal cord stimulation","EXPERIMENTAL",null,[13],"Device: Robot-assisted gait training and transcutaneous spinal cord stimulation in chronic non-ambulatory stroke survivors: pilot RCT trial",{"label":15,"type":16,"description":11,"interventionNames":17},"Robot assisted gait training alone","ACTIVE_COMPARATOR",[18],"Device: Robot assisted gait training alone",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Robot-assisted gait training and transcutaneous spinal cord stimulation in chronic non-ambulatory stroke survivors: pilot RCT trial","Participants in the experimental group will receive 30 minutes of robot assisted gait training (RAGT) transcutaneous spinal cord stimulation 3 times per week, 8 weeks, totaling 24 sessions. The gait training will utilize a treadmill equipped with a partial-body-weight support system and a lab-developed RAGT device. The RAGT protocol will be the same as in the control group",[9],{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":11},"Participants in the control group will receive 30 minutes of assisted gait training (RAGT), 3 times per week, for 8 weeks, totaling 24 sessions. The gait training will utilize a treadmill equipped with a partial-body-weight support system and a lab-developed RAGT device",[15],[29],{"name":30,"affiliation":5,"role":31},"Wen Liu, PhD","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":11,"email":37},"Mustapha Mangdow, PT. MS","CONTACT","913-2421754","mmangdow@kumc.edu",[39],{"facility":40,"status":11,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Neuromuscular Research Laboratory","Kansas City","Kansas","66160","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-94.62746,39.11417,{"lat":50,"lon":49},[53,56],{"name":54,"role":35,"phone":55,"phoneExt":11,"email":37},"Mustapha Mangdow, PT, MS","9132421754",{"name":30,"role":35,"phone":11,"phoneExt":11,"email":57},"wliu@kumc.edu",{"type":31,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Wen Liu, Ph.D.","Professor","100610356","walking-and-tscs-in-non-ambulatory-stroke-survivors-100610356",false,"NCT07226518","Walking and tSCS in Non-ambulatory Stroke Survivors","Robot-assisted Gait Training and Transcutaneous Spinal Cord Stimulation in Chronic Non-ambulatory Stroke Survivors: Pilot RCT Trial","Inclusion Criteria:\n\n1. Age 18-80 years at time of consent\n2. All genders included.\n3. Chronic ischemic or hemorrhagic stroke \\>=6 months, with limited within-home comfortable walking speed \\\u003C= 0.49 m\u002Fs and unable to walk independently in community (FAC \\\u003C= 3)\n4. Able to communicate with investigators, follow 2-step command, and correctly answer consent comprehension questions in English.\n5. Currently not participating in treadmill walking exercises or exercises involving weight-bearing activities.\n6. Have physicians' approval for exercise and be in a stable medical condition\n\nExclusion Criteria:\n\n1. Hospitalization for cardiac or pulmonary disease within the past 3 months\n2. Have musculoskeletal disorders that prevent the participant from participating in the exercise\n3. Blood pressure higher than 200\u002F110 mm Hg\n4. Significant ataxia or unilateral spatial neglect (score of 2 on NIH stroke scale item 7 or 11)\n5. Reported pain that limits or interferes with activities of daily living and physical activity\u002Fexercise\n6. Diagnosis of other neurological diseases (multiple sclerosis, Alzheimer's disease, Parkinson's disease)\n7. Diagnosis of severe depression (HADS score 15-21)\n8. Unable to speak or understand English, and travel to the research laboratory.\n9. Contraindications to tSCS and TMS","ALL","18 Years","80 Years",{"count":72,"type":73},20,"ESTIMATED","INTERVENTIONAL",[76],"NA","Rehabilitation interventions commonly used for stroke survivors include task-specific training, balance and strength exercises, and the use of assistive devices to enhance mobility and independence. Advanced technologies, such as body-weight-supported treadmill systems and robotic devices, may be employed when appropriate. Current rehabilitation therapies for stroke survivors are moderately effective with a limited effect size, especially in stroke survivors with severe impairment. Novel therapies, such as transcutaneous spinal cord stimulation (tSCS), may further improve outcomes in the target population. This pilot study will allow us to examine the feasibility and gather pilot data on a combined intervention of assistive gait training and tSCS in non-ambulatory stroke survivors.",[79,80,81],"Chronic Stroke Survivors","Chronic Stroke Patients","Stroke",[83,84,85,86],"stroke gait rehabilitation","Transcutaneous spinal cord stimulation","Non invasive spinal cord stimulation","Robot assisted gait training","NOT_YET_RECRUITING","2025-11-07",{"date":90,"type":91},"2025-11-10","ACTUAL",{"date":93,"type":73},"2026-01-01",{"date":95,"type":73},"2026-12-31",{"name":5,"class":6},1]