[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599223":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":59,"collaborators":61,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":73,"enrollmentInfo":74,"targetDuration":18,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":40,"whyStopped":18,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Colorado State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"The walnut group","EXPERIMENTAL","The intervention group will provide 10g of walnuts daily to their infant for 7 months.",[13],"Other: Infant walnut intake",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","The control group will be asked to limit walnuts and tree nuts.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Infant walnut intake","The intervention group will receive walnuts at 10 g\u002Fday, and the control group will be advised to avoid walnuts\u002Ftree nuts during the intervention. The purpose of this research is to learn more about how walnuts as a first food in infants impact immunity and the development of bacteria living in your baby's gut.",[9],[25],{"name":26,"affiliation":5,"role":27},"Minghua Tang, Phd","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Nathan Campbell, MS","CONTACT","7655436716","Nathan.Campbell@colostate.edu",{"name":35,"role":31,"phone":18,"phoneExt":18,"email":36},"Kinzie Matzeller, MS RDNCLC","kinzie.matzeller@colostate.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Food Science and Human Nutrition Clinical Research Laboratory","RECRUITING","Fort Collins","Colorado","80523","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-105.08442,40.58526,{"lat":50,"lon":49},[53,55,57],{"name":54,"role":31,"phone":32,"phoneExt":18,"email":33},"Nathan Campbell, M.S.",{"name":56,"role":31,"phone":18,"phoneExt":18,"email":36},"Kinzie Matzeller, M.S., RDN, CLC",{"name":58,"role":27,"phone":18,"phoneExt":18,"email":18},"Minghua Tang, Phd.",{"type":60,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[62],{"name":63,"class":6},"California Walnut Commission","100599223","walnuts-as-an-infant-solid-food-for-health-100599223",false,"NCT07081698","Walnuts as an Infant Solid Food for Health","Walnut as a First Food During Complementary Feeding on Gut Microbiota and Immunity Development in Breastfed Infants","WISH","Inclusion Criteria:\n\n* Full term: gestational age ≥ 37 weeks\n* Generally healthy without conditions that would affect normal growth\n* No significant consumption of complementary food (e.g., no more than 1 oz of solid foods per week)\n* Exclusively breastfed (\\\u003C 2 weeks of cumulative formula exposure)\n\nExclusion Criteria:\n\n* Adults unable to consent\n* Pregnant women\n* Prisoners","ALL","5 Months",{"count":75,"type":76},90,"ESTIMATED","INTERVENTIONAL",[79],"NA","The objective is to investigate the effect of walnuts on gut microbiota, inflammatory markers, atopic dermatitis status, and indices of allergy outcomes in breastfed infants during early complementary feeding.\n\nThe three primary aims include:\n\nAim 1: Evaluate the effect of walnut consumption on gut microbiota structure and function, inflammation, atopic dermatitis, and allergy outcomes.\n\nAim 2: Evaluate the impact of walnut consumption on infant growth trajectories and risk of overweight.\n\nAim 3 (exploratory): Identify walnut-specific food signatures that are associated with gut microbiota and immunity biomarkers using a novel nutri-metabolomics technique.",[82,83,84],"Gut -Microbiota","Inflammatory Markers","Infant Development",[86,87,88,89,90,91],"Walnut","Microbiome","Infant","Pediatric","Nutrition","Health","2025-07-16",{"date":94,"type":95},"2025-07-23","ACTUAL",{"date":97,"type":95},"2025-05-18",{"date":99,"type":76},"2027-12-31",{"name":5,"class":6},1]