[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544691":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":57,"collaborators":39,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":39,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":39,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":85,"whyStopped":39,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"The Second Hospital of Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Washed microbiota transplantation","EXPERIMENTAL","Patients take four capsules containing washed microbiota once a day for five consecutive days",[13],"Drug: Washed Microbiota Transplantation",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Patients take four capsules in the same packaging as the experimental group once a day for five consecutive days",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Washed Microbiota Transplantation",[9],[26],"Fecal Microbiota Transplantation",{"type":22,"name":15,"description":17,"armGroupLabels":28,"otherNames":29},[15],[30],"Capsule",[32],{"name":33,"affiliation":5,"role":34},"Faming Zhang, MD,PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","086-25-58509883",null,"fzhang@njmu.edu.cn",[42],{"facility":43,"status":39,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University","Nanjing","Jiangsu","210011","China","CN",{"type":50,"coordinates":51},"Point",[52,53],118.77778,32.06167,{"lat":53,"lon":52},[56],{"name":33,"role":37,"phone":38,"phoneExt":39,"email":40},{"type":34,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":39,"oldOrganization":39},"Faming Zhang","Professor, Gastroenterology","100544691","washed-microbiota-transplantation-for-allergic-rhinitis-100544691",false,"NCT06372184","Washed Microbiota Transplantation for Allergic Rhinitis","Efficacy and Safety of Washed Microbiota Transplantation for Allergic Rhinitis: A Randomized, Double-blind, Placebo-controlled Study","Inclusion Criteria:\n\n1. Age 18-65 years old.\n2. Meets the diagnostic criteria for allergic rhinitis.\n3. rTNSS score greater than or equal to 6 points.\n4. The subject or his\u002Fher legal representative gives informed consent, fully understands the purpose of the study, is able to communicate effectively with the investigator, and comprehends and complies with the requirements set forth in the study.\n\n   \\-\n\nExclusion Criteria:\n\n1. Patients with acute nasosinusitis or upper respiratory tract infection.\n2. Patients diagnosed with chronic sinusitis, nasal septum deviation, nasal polyps, nasal tumors, and other nasal diseases or have undergone nasal surgery.\n3. Antibiotics, PPI, probiotics, and other drugs that alter gut microbiota were used in the past two weeks.\n4. Patients with poor lung function.\n5. Patients with severe liver, kidney, and heart diseases\n6. Patients with known psychiatric or neurological diseases.\n7. Patients who use antihistamines, glucocorticoids, decongestants, mast cell membrane stabilizers, leukotriene antagonists in the past two weeks.\n8. According to the judgment of the investigator, the subjects are not suitable to participate in this clinical study, or participation in this clinical study cannot guarantee the rights and interests of the subjects.\n\n   \\-","ALL","18 Years","65 Years",{"count":71,"type":72},32,"ESTIMATED","INTERVENTIONAL",[75],"NA","Allergic rhinitis (AR) is characterized by sneezing, nasal congestion, nasal itching and nasal leakage and is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens. Increasing evidence showed that gut microbiota could influence the development of AR, and we found that washed microbiota transplantation (WMT) could improve nasal symptoms in clinical practice. This clinical trial aims to evaluate the efficacy and safety of WMT for AR.",[78],"Rhinitis, Allergic",[80,81,82,83,84],"washed microbiota transplantation","allergic rhinitis","reflective total nasal symptom score","rhinoconjunctivitis quality of life questionnaire score","gut microbiota","NOT_YET_RECRUITING","2024-05-05",{"date":88,"type":89},"2024-05-07","ACTUAL",{"date":91,"type":72},"2024-06-01",{"date":93,"type":72},"2029-10-01",{"name":5,"class":6},1]