[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565265":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":100,"collaborators":26,"id":104,"slug":105,"hasResults":106,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":26,"eligibilityCriteria":110,"healthyVolunteers":111,"sex":112,"minAge":113,"maxAge":26,"enrollmentInfo":114,"targetDuration":26,"studyType":117,"phases":118,"briefSummary":120,"conditions":121,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"City University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"We-INtervention group","EXPERIMENTAL","The interventionists at each study site will be either healthcare providers (e.g., nurses), social workers, or psychologists with at least 3 years of experience serving HIV-serodiscordant male couples.",[13],"Behavioral: We-INtervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual care group","ACTIVE_COMPARATOR","The participants in the control condition will receive regular care.",[19],"Behavioral: Usual Care Group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","We-INtervention","The We-INtervention focuses on the relationship dynamics of HIV-serodiscordant male couples. In developing the intervention, we reviewed relevant theories and frameworks, such as the cognitive transactional model, the systemic transactional model, the dyadic illness management model, and the intersectional framework of stigma. The three weekly 60-minute sessions are Session 1: We-disease appraisal. Despite stigma related to their dual minority identities, couples develop a perception of HIV as a shared disease, enhancing illness control. Session 2: Couple communication. Couples undertake skill-building exercises on effective communication techniques to strengthen their relationship. Session 3: Dyadic coping. Couples learn to optimize preference and value assessments in HIV management. A few skill-building exercises help them mobilize and maintain mutual support and develop joint problem-solving skills.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Usual Care Group","The participants in the control condition will receive health information pamphlets. The HIV-seropositive partners will receive information on HIV-related knowledge (e.g., symptoms, comorbidity, stages, and opportunistic infection), treatment (e.g., ART and side effects), and management (e.g., nutrition and mental health). The HIV-seronegative partner will receive information on HIV transmission (e.g., risk factors), prevention (e.g., safe sex and PrEP), and testing.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Nancy Xiaonan Yu, PhD","CONTACT","34429436","nancy.yu@cityu.edu.hk",{"name":38,"role":34,"phone":35,"phoneExt":26,"email":39},"Jianhua Hou, MS","jianhuhou2-c@my.cityu.edu.hk",[41,59,73,86],{"facility":42,"status":43,"city":44,"state":45,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Fangzhouai Garden","RECRUITING","Xiamen","Fujian","China","CN",{"type":49,"coordinates":50},"Point",[51,52],118.08187,24.47979,{"lat":52,"lon":51},[55],{"name":56,"role":34,"phone":57,"phoneExt":26,"email":58},"Tianqi Lin","13043041203","a00886@qq.com",{"facility":60,"status":43,"city":61,"state":62,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Guangzhou Yuele Healthcare Service Center","Guangzhou","Guangdong",{"type":49,"coordinates":64},[65,66],113.25,23.11667,{"lat":66,"lon":65},[69],{"name":70,"role":34,"phone":71,"phoneExt":26,"email":72},"Weizan Zhu","13632346142","412845528@qq.com",{"facility":74,"status":43,"city":75,"state":62,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Community Always There","Shenzhen",{"type":49,"coordinates":77},[78,79],114.0683,22.54554,{"lat":79,"lon":78},[82],{"name":83,"role":34,"phone":84,"phoneExt":26,"email":85},"Honglin Liu","18929303315","990361066@qq.com",{"facility":87,"status":43,"city":88,"state":89,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Jin Tang Six-Color Rainbow Healthcare Center","Chengdu","Sichuan",{"type":49,"coordinates":91},[92,93],104.06667,30.66667,{"lat":93,"lon":92},[96],{"name":97,"role":34,"phone":98,"phoneExt":26,"email":99},"Shanzhi Feng","13348854440","owen.feng@outlook.cl",{"type":101,"investigatorFullName":102,"investigatorTitle":103,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Dr. Nancy Xiaonan Yu","Professor","100565265","we-intervention-among-chinese-hiv-serodiscordant-male-couples-100565265",false,"NCT06639932","We-INtervention Among Chinese HIV-serodiscordant Male Couples","Evaluating the Effects of the We-INtervention Among Chinese HIV-serodiscordant Male Couples in a Randomized Controlled Trial","Inclusion criteria:\n\n1. both partners are male,\n2. both partners are aged 18 or above,\n3. both partners report being in a committed relationship for at least 3 months,\n4. one partner is HIV-seropositive and the other partner is HIV-seronegative (i.e., serodiscordant couple),\n5. both partners have disclosed their serostatus to each other, and\n6. both partners are willing to participate in this study.\n\nExclusion criteria:\n\n1. either partner is unable to complete the assessment due to a low education level or to physical or psychological constraints and\n2. either partner has been diagnosed with another chronic disease (e.g., cancer and coronary heart disease).",true,"MALE","18 Years",{"count":115,"type":116},320,"ESTIMATED","INTERVENTIONAL",[119],"NA","HIV-serodiscordant male couples, in which one male partner is HIV-seropositive and the other is HIV-seronegative, experience multiple risks in HIV care and prevention. As stigma often hinders such couples' access to support and services, leveraging their relational resources is crucial for optimizing their outcomes. The proposed study will assess the efficacy of the three-session We-INtervention focusing on their relationship dynamics to enhance Chinese HIV-serodiscordant male couples' health and well-being.\n\nA total of 160 Chinese HIV-serodiscordant male couples (320 individuals: 160 HIV-seropositive and 160 HIV-seronegative) will be randomized at a 1:1 ratio to either the intervention or control arm. In the intervention arm, the We-INtervention will be delivered to both partners of each couple separately. In the control arm, each couple will receive health information pamphlets.",[122],"HIV","2026-01-18",{"date":125,"type":126},"2026-01-21","ACTUAL",{"date":128,"type":126},"2025-09-01",{"date":130,"type":116},"2027-06-30",{"name":5,"class":6},4]