[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316605":3},{"organization":4,"armGroups":7,"interventions":36,"overallOfficials":42,"centralContacts":47,"locations":56,"responsibleParty":70,"collaborators":74,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":42,"eligibilityCriteria":85,"healthyVolunteers":82,"sex":86,"minAge":87,"maxAge":42,"enrollmentInfo":88,"targetDuration":42,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":58,"whyStopped":42,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,14,18,22,28,32],{"label":9,"type":10,"description":11,"interventionNames":12},"Chronic stroke MCI Electromyogram (EMG) pairs","EXPERIMENTAL","Decoupling 2 muscles at a time with MCI",[13],"Behavioral: MCI",{"label":15,"type":10,"description":16,"interventionNames":17},"Chronic stroke MCI EMG triplets","Decoupling 3 muscles at a time with MCI",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Chronic stroke MCI while reaching","Decoupling muscles with MCI while reaching to targets",[13],{"label":23,"type":24,"description":25,"interventionNames":26},"Chronic stroke Sham MCI","SHAM_COMPARATOR","Sham control group",[27],"Behavioral: Sham MCI",{"label":29,"type":10,"description":30,"interventionNames":31},"Acute stroke MCI","Decoupling muscles with MCI in acute stroke subjects",[13],{"label":33,"type":24,"description":34,"interventionNames":35},"Acute stroke Sham MCI","Acute stroke subjects sham comparator",[27],[37,43],{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"BEHAVIORAL","MCI","EMG-controlled game",[29,15,9,19],null,{"type":38,"name":44,"description":45,"armGroupLabels":46,"otherNames":42},"Sham MCI","Sham control game",[33,23],[48,53],{"name":49,"role":50,"phone":51,"phoneExt":42,"email":52},"Marc W Slutzky, MD, PhD","CONTACT","3125034653","mslutzky@northwestern.edu",{"name":54,"role":50,"phone":42,"phoneExt":42,"email":55},"Cynthia Gorski","cynthia.gorski@northwestern.edu",[57],{"facility":5,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":42},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-87.65005,41.85003,{"lat":68,"lon":67},{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"PRINCIPAL_INVESTIGATOR","Marc Slutzky","Associate Professor",[75,77],{"name":76,"class":6},"Shirley Ryan AbilityLab",{"name":78,"class":79},"National Institutes of Health (NIH)","NIH","100316605","wearable-mci-to-reduce-muscle-co-activation-in-acute-and-chronic-stroke-100316605",false,"NCT03401762","Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke","Inclusion Criteria:\n\nChronic stroke participants\n\n* Hemiparesis from first ever stroke at least 6 months prior to screening\n* Severe motor impairment (FMA of 7-30)\n* At least some voluntary shoulder and elbow muscle activation.\n\nAcute stroke participants\n\n* Hemiparesis from first ever stroke within the past 21 days\n* Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors\n\nExclusion Criteria:\n\n* Cognitive impairment with at least moderately impaired attention, or unable to follow instructions of the MCI task\n* Visual impairment (such as hemianopia) preventing full view of the screen\n* Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest).\n* Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study\n* Inability to understand or follow commands in English due to aphasia or other reason\n* Diffuse or multifocal infarcts\n* Substantial arm pain preventing participation for 90 minutes a day\n* New spasticity treatment (pharmacological or Botox)","ALL","21 Years",{"count":89,"type":90},96,"ESTIMATED","INTERVENTIONAL",[93],"NA","The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke.\n\nImpaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations.\n\nThis randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.",[96,97],"Stroke","Stroke, Acute",[99],"rehabilitation","2026-04-07",{"date":102,"type":103},"2026-04-08","ACTUAL",{"date":105,"type":103},"2018-01-15",{"date":107,"type":90},"2027-04",{"name":5,"class":6},1]