[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590676":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":13,"centralContacts":17,"locations":27,"responsibleParty":51,"collaborators":53,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Shirley Ryan AbilityLab","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"Infants with Typical Tone",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Infants with Low Tone",[14],{"name":15,"affiliation":5,"role":16},"Arun Jayaraman, PT, PhD","PRINCIPAL_INVESTIGATOR",[18,23],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Rachel Andersen","CONTACT","312-238-1476","randersen@sralab.org",{"name":24,"role":20,"phone":25,"phoneExt":10,"email":26},"Megan O'Brien, PhD","312-238-2289","mobrien02@sralab.org",[28,45],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Ann & Robert H. Lurie Children's Hospital of Chicago","RECRUITING","Chicago","Illinois","60611","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-87.65005,41.85003,{"lat":40,"lon":39},[43],{"name":44,"role":16,"phone":10,"phoneExt":10,"email":10},"Raye-Ann Odegaard deRegnier, MD",{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},{"type":37,"coordinates":47},[39,40],{"lat":40,"lon":39},[50],{"name":15,"role":16,"phone":10,"phoneExt":10,"email":10},{"type":16,"investigatorFullName":15,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Principal Investigator",[54,56],{"name":55,"class":6},"Ann & Robert H Lurie Children's Hospital of Chicago",{"name":57,"class":6},"Northwestern University","100590676","wearable-sensors-to-detect-atypical-muscle-activation-in-young-infants-100590676",false,"NCT06970522","Wearable Sensors to Detect Atypical Muscle Activation in Young Infants","Early Detection of Atypical Neuromuscular Development Using Wearable Sensors and Video: A Comparative Analysis of Muscle and Motion","Inclusion Criteria:\n\n* For Infants with low tone:\n* Hospitalized in the NICU\n* AND \\>38 weeks post-menstrual age\n* AND abnormal normal brain imaging OR Apgar score \\\u003C7 at five minutes with umbilical cord pH (if obtained) \\\u003C7.15\n* AND 2 or more warning signs for muscle tone or posture using the HNNE short form\n* AND legal guardian able and willing to give written consent and comply with study procedures\n* For Infants with typical tone:\n* Born at 38-41 weeks of gestation\n* AND hospitalized after birth in the NICU OR well newborn nursery\n* AND infants with appropriate for gestational age birth weight\n* AND HNNE exam (short proforma) normal with no warning signs for any parameter\n* AND legal guardian able and willing to give written consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Infants of Both Low Tone and Typical Tone Cohorts:\n* Missing or incomplete limbs (such as from amputation or congenital limb defects).\n* Open wounds or skin breakdown on the limbs or torso.\n* Presence of known genetic syndrome or congenital anomalies requiring surgery or affecting function\n* Use of sedative medications (may include phenobarbital if level stable and therapeutic)\n* Legal guardian unable to give written consent and comply with study procedures.\n* Does not receive medical clearance from a physician to participate in the study if the individual is receiving inpatient care.","ALL","0 Months","8 Weeks",{"count":69,"type":70},40,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and\u002For identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.",[74,75,76],"Neuromuscular Disorders","Motor Development","Muscle Tone",[78,79],"Early Detection","Wearable Sensors","2026-03-24",{"date":82,"type":83},"2026-03-25","ACTUAL",{"date":85,"type":83},"2025-06-25",{"date":87,"type":70},"2026-12-31",{"name":5,"class":6},2]