[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586018":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":37,"locations":47,"responsibleParty":67,"collaborators":19,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":19,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":19,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":19,"overallStatus":50,"whyStopped":19,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Periprosthetic Fracture Knee Repaired","EXPERIMENTAL","The one and only group will be participants that have undergone revision surgery for at least 1\\> year prior for their periprosthetic distal knee fracture.",[13],"Other: Periprosthetic Fracture Knee Repaired CT Scans",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Periprosthetic Fracture Knee Repaired CT Scans","The investigators will be assessing the use of weight-bearing CT and conventional CT, specifically its imaging, with RSA-like software, for analyzing fracture healing for a periprosthetic distal knee fracture.",[9],null,[21,24,28,32,35],{"name":22,"affiliation":5,"role":23},"Matthew Teeter, PhD","STUDY_DIRECTOR",{"name":25,"affiliation":26,"role":27},"Brent Lanting, MD","Lawson Health Sciences Centre","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":30,"role":31},"Lyndsay Somerville, PhD","London Health Sciences Centre","STUDY_CHAIR",{"name":33,"affiliation":34,"role":31},"Patrick J Mixa, MD","Western University",{"name":36,"affiliation":30,"role":31},"James Howard, MD",[38,43],{"name":25,"role":39,"phone":40,"phoneExt":41,"email":42},"CONTACT","519-685-8500","33335","brent.lanting@lhsc.on.ca",{"name":44,"role":39,"phone":45,"phoneExt":19,"email":46},"Farzan Mohammadreza, MSc","5197298079","farzan.mohammadreza@lhsc.on.ca",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"University Hospital - London Health Sciences Centre","RECRUITING","London","Ontario","N6A 5A5","Canada","CA",{"type":57,"coordinates":58},"Point",[59,60],-81.23304,42.98339,{"lat":60,"lon":59},[63,64],{"name":25,"role":39,"phone":40,"phoneExt":41,"email":42},{"name":65,"role":39,"phone":66,"phoneExt":19,"email":46},"Farzan Mohammadreza Mohammadreza, MSc","519-729-8079",{"type":68,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100586018","weight-bearing-ct-and-conventional-periprosthetic-distal-knee-fractures-100586018",false,"NCT06909916","Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures","Assessment of Bone Displacement Under Loading Following Distal Femur Periprosthetic Fracture Repair With Weight-Bearing CT and Conventional CT","Inclusion Criteria:\n\n* Underwent revision surgery for repair of a distal femur fracture surrounding a primary TKA femoral component using a fracture fixation plate \\>1 year\n* Age 50-90 years\n* Body mass index up to 40kg\u002Fm2\n* Able to provide informed consent\n* Able and willing to do study assessments and follow instructions\n\nExclusion Criteria:\n\n* Does not understand English\n* Undergone revision surgery for any other indication\n* Received Intramedullary nail or distal femur replacement\n* Cannot independently stand on one leg in the weight-bearing CT during the inducible displacement exam","ALL","50 Years","90 Years",{"count":80,"type":81},20,"ESTIMATED","INTERVENTIONAL",[84],"NA","Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function. However, for patients that have suffered an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA, they may receive sub-optical care due to a lack of a trustworthy assessments for component fixation and fracture healing in the literature. The prevalence of TKA surgeries is increasing annually and is projected to rise further due to an ageing population and obesity issue. By extension to this primary surgery, more Canadians will require an invasive revision surgery that risks patient morbidity and mortality. Thus, it is imperative to set a standard for fixation and bone healing assessments to lessen revision burdens and improve patient outcomes. CT imaging can effectively visualize areas of incomplete bone ingrowth that may be hidden from overlapping anatomy on plain radiographs, which remains the go-to imaging modality for orthopaedic surgeons to assess periprosthetic fracture healing. The purpose of this prospective cross-sectional study is to examine the efficacy of weight-bearing CT as a diagnostic tool for 20 participants who experienced a distal femur periprosthetic fracture and underwent revision surgery using a fracture fixation plate and screws. Participants will be scanned under loaded and unloaded conditions. Radiographic outcomes will be evaluated, including bone segment displacement and its relation to participants' reports of pain.",[87],"Periprosthetic Fracture Around Prosthetic Joint Implant","2025-03-27",{"date":90,"type":91},"2025-04-04","ACTUAL",{"date":93,"type":91},"2024-06-20",{"date":95,"type":81},"2025-05",{"name":5,"class":6},1]