[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596297":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":33,"locations":39,"responsibleParty":66,"collaborators":32,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":32,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":32,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":91,"overallStatus":95,"whyStopped":32,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Sakarya University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early Scalp Block Group","ACTIVE_COMPARATOR","Patients in this group will receive a scalp block with 0.25% bupivacaine (20 mL) administered under ultrasound guidance after the induction of general anesthesia but prior to head pinning",[13],"Procedure: Early Scalp Block Group",{"label":15,"type":10,"description":16,"interventionNames":17},"Postoperative Scalp Block Group","Patients in this group will receive a scalp block with 0.25% bupivacaine (20 mL) administered under ultrasound guidance at the end of surgery, before emergence from anesthesia.",[18],"Procedure: Late Scalp Block Group",[20,26],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Following induction of general anesthesia and prior to head pinning (Mayfield clamp placement), a scalp block was performed under aseptic conditions using 20 mL of 0.25% bupivacaine.\n\nThe block targeted six sensory nerves that innervate the scalp: Supraorbital nerve, Supratrochlear nerve, Auriculotemporal nerve ,Zygomaticotemporal nerve, Greater occipital nerve, Lesser occipital nerve.\n\nEach nerve was infiltrated subcutaneously at its anatomical location using a 25-gauge needle, with the total volume distributed evenly or proportionally across the injection sites.",[9],[25],"Pre-pinning Scalp Block Group",{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Late Scalp Block Group","In the pre-emergence group, the scalp block was performed at the end of surgery but before emergence from general anesthesia, while the patient was still under deep anesthesia.\n\nUnder strict aseptic conditions, 20 mL of 0.25% bupivacaine was administered to block the following six sensory nerves innervating the scalp: Supraorbital nerve, Supratrochlear nerve, Auriculotemporal nerve, Zygomaticotemporal nerve, Greater occipital nerve, Lesser occipital nerve.\n\nThe local anesthetic was injected subcutaneously at the anatomical landmarks of each nerve using a 25-gauge needle. The total volume was distributed evenly or proportionally depending on the area. No additional surgical stimulation occurred after the block, and extubation followed routine emergence from anesthesia.",[15],[31],"Pre-emergence Scalp Block Group",null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Muhammed halit TEKECİ","CONTACT","+905389334248","halittekeci@gmail.com",[40],{"facility":41,"status":32,"city":42,"state":32,"zip":43,"country":44,"countryCode":32,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Sakarya University Training and Research Hospital","Sakarya","54290","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],32.07583,39.50333,{"lat":49,"lon":48},[52,54,58,61,64],{"name":53,"role":36,"phone":37,"phoneExt":32,"email":38},"Muhammed Halit Tekeci, Specialist",{"name":55,"role":36,"phone":56,"phoneExt":32,"email":57},"Havva Kocayiğit, Assoc. Prof.","+90425950020","havvakocayigit@gmail.com",{"name":59,"role":60,"phone":32,"phoneExt":32,"email":32},"Muhammed Halit TEKECİ, Specialist","PRINCIPAL_INVESTIGATOR",{"name":62,"role":63,"phone":32,"phoneExt":32,"email":32},"Havva Kocayigit, Assoc. Prof.","SUB_INVESTIGATOR",{"name":65,"role":63,"phone":32,"phoneExt":32,"email":32},"Halil Kızılışık, Specialist",{"type":60,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Muhammed Halit Tekeci, MD","Anesthesiology and Reanimation Specialist, M.D.","100596297","when-to-block-timing-of-scalp-block-in-craniotomy-100596297",false,"NCT07043621","When to Block? Timing of Scalp Block in Craniotomy","Scalp Block Before Incision or Before Emergence in Craniotomy: A Randomized Controlled Evaluation of Effectiveness and Recovery Quality Via QoR-40","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years.\n* Scheduled for craniotomy under general anesthesia.\n* ASA physical status classification I to III.\n* Glasgow Coma Scale (GCS) score of 15 at the time of emergence from anesthesia.\n* Provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Chronic use of analgesic medications prior to surgery.\n* Glasgow Coma Scale (GCS) score below 15 postoperatively.\n* Allergy or hypersensitivity to local anesthetics or opioids used in the study.\n* Contraindications for scalp block or patient-controlled analgesia.\n* Patients with severe hepatic, renal, or cardiac dysfunction.\n* Patients unable to comprehend or complete the QoR-40 questionnaire.","ALL","18 Years","80 Years",{"count":80,"type":81},60,"ESTIMATED","INTERVENTIONAL",[84],"NA","This study aims to evaluate the effect of scalp block timing-whether administered preoperatively or postoperatively-on postoperative recovery quality in patients undergoing craniotomy. The recovery quality will be assessed using the validated Quality of Recovery-40 (QoR-40) questionnaire. A total of 60 patients, aged 18-80 years, classified as ASA I-III and with a Glasgow Coma Scale (GCS) score of 15 upon admission to the recovery unit, will be enrolled. The primary outcome is the QoR-40 score. Secondary outcomes include hemodynamic changes and pain intensity measured by the Visual Analog Scale (VAS).",[87,88,89,90],"Scalp Block","Regional Anesthesia","Craniotomy Surgery","QoR-40",[87,92,93,94],"Craniotomy surgery","analgesia","postoperative pain","NOT_YET_RECRUITING","2025-06-27",{"date":98,"type":99},"2025-06-29","ACTUAL",{"date":101,"type":81},"2025-06",{"date":103,"type":81},"2025-12",{"name":5,"class":6},1]