[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586047":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":51,"collaborators":55,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":73,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"ART Fertility Clinics LLC","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Young (age range 25-35), healthy , who want to undergo ovarian stimulation for oocyte vitrification.",null,"\\- Initial Assessment of Volunteers for Inclusion in the study.\n\nOnce included, volunteers will need to be assessed 8 times during the study period, with 6 fMRI scans:\n\n* Natural menstrual cycle (depending on cycle duration: around 26-35 days)\n\n  1. Basal (day 2-3 of the menstrual cycle)\n  2. Monitoring of follicle growth (no fMRI at these monitoring dates)\n  3. Day of LH surge +\u002F-1 day (around day 14, 2-3 hormonal checks will be needed to identify Ovulation Day)\n  4. Mid-Luteal (6-7 days after ovulation)\n* Stimulated Cycle 5. Basal (day 2-3 of the menstrual cycle) 6. Standard monitoring during ovarian stimulation (no fMRI at these monitoring dates) 7. Day between administration of final oocyte maturation \\& Oocyte Pick-Up (OPU) 8. Mid-luteal (6-7 days after OPU)\n\nEvery stage will include a blood test for hormonal evaluation, vaginal ultrasound for follicular count \\& sizing, administration of MRI protocol. The first visit will include buccal swab.",[13],"Diagnostic Test: Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.",[15],{"type":16,"name":17,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Raquel Del Gallego, PhD","CONTACT","+971 2 6528000","raquel.delgallego@artfertilityclinics.com",[26,44],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","Abu Dhabi","Abu Dhabi Emirate","00000","United Arab Emirates","AE",{"type":34,"coordinates":35},"Point",[36,37],54.39696,24.45118,{"lat":37,"lon":36},[40],{"name":41,"role":22,"phone":42,"phoneExt":10,"email":43},"Jonalyn Edades, Research Coordinator","+97126528000","jonalyn.edades@artfertilityclinics.com",{"facility":5,"status":27,"city":28,"state":29,"zip":45,"country":31,"countryCode":32,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},"60202",{"type":34,"coordinates":47},[36,37],{"lat":37,"lon":36},[50],{"name":41,"role":22,"phone":42,"phoneExt":10,"email":43},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dr. Raquel Del Gallego Bonilla","Head Clinical Data Management Unit",[56,58],{"name":57,"class":6},"Khalifa University for Science and Technology",{"name":59,"class":6},"New York University Abu Dhabi","100586047","whole-brain-dynamics-in-the-natural-menstrual-cycle-vs-an-ovarian-stimulated-cycle-impact-of-hormonal-fluctuations-on-healthy-women-undergoing-ovarian-stimulation-100586047",false,"NCT06910293","Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation","Inclusion Criteria:\n\n* Age group: 25 - 35 years old\n* BMI: 20 - 30\n* Anti-Mullerian Hormone (AMH): 1.3 - 5.9 ng\u002Fml\n* Regular Menstrual Cycle: 26-35 days\n* In case of previous use of hormonal contraception: wash-out period of 3 month\n* Meet standard safety and eligibility criteria for MRI scanning, including the absence of contraindications such as metallic implants, claustrophobia, or other medical conditions that preclude MRI\n\nExclusion Criteria:\n\n* History of ovarian surgery\n* Pathology of the ovaries\n* Mental health disorders\n* Use of medication influencing brain function\n* Ongoing use of hormonal contraception (this would include OCP, but also patches and Mirena containing IUD)",true,"FEMALE","25 Years","35 Years",{"count":71,"type":72},15,"ESTIMATED","8 Weeks","OBSERVATIONAL","The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it with the corresponding phases of a natural menstrual cycle (early follicular, pre-ovulatory, mid-luteal) in the same woman. Brain activity patterns will be examined using resting-state fMRI in a sample of young, healthy, naturally cycling women.",[77,78,79,80],"Neural Activity","Brain Function","Neurodynamics","Brain Connectivity",[82,83,84,85,86],"Menstrual Cycle","Ovarian Stimulated Cycle","Endocrine Profile","neural activity","neurodynamics","2026-06-22",{"date":89,"type":90},"2026-06-23","ACTUAL",{"date":92,"type":90},"2025-04-07",{"date":94,"type":72},"2026-12-31",{"name":5,"class":6},2]