[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639542":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Cerebrovascular group",null,"Participants in the cerebrovascular group receive head and neck magnetic resonance (MR) examination, transcranial Doppler (TCD) and cervical ultrasound. These examinations are used to screen cerebrovascular structural lesions, intracranial hemodynamic disorders and cervical atherosclerotic plaques, so as to identify early risk factors for stroke and cerebrovascular diseases.",{"label":13,"type":10,"description":14,"interventionNames":10},"Tumor Group","The tumor group undergoes methylation pan-cancer detection. This non-invasive and high-sensitivity assay is applied to screen aberrant methylation of tumor-related genes, covering ten common cancers including cervical cancer, esophageal cancer, lung squamous cell carcinoma, prostate cancer, liver cancer, lung adenocarcinoma, colon cancer, rectal cancer, gastric cancer and pancreatic cancer, enabling early identification of potential malignant tumor risk in the population.",{"label":16,"type":10,"description":17,"interventionNames":10},"Epigenetic Age Group","The epigenetic age group accepts physiological age methylation detection combined with Vibration-Controlled Transient Elastography (VCTE). Methylation profiling of age-related CpG sites is used to evaluate individual physiological aging status, while VCTE is supplemented to assess liver elasticity and related metabolic characteristics.",[19],{"name":20,"affiliation":21,"role":22},"Jiansong Ji, PhD","The Central Hospital of Lishui City","STUDY_CHAIR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Jingping Sun, PhD","CONTACT","86-18504713450","lszxyysunjingping@yeah.net",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Lishui Central Hospital","RECRUITING","Lishui","Zhejiang","323000","China","CN",{"type":39,"coordinates":40},"Point",[41,42],119.91029,28.46042,{"lat":42,"lon":41},[45],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100639542","whole-life-investigation-of-lishui-longevity-100639542",false,"NCT07592962","Whole-life Investigation of Lishui Longevity","Whole-life Investigation of Lishui Longevity Cohort Study","WILL","Inclusion Criteria:\n\n* Aged 30 to 80 years old; male-to-female ratio of 1:1; permanent residents in Lishui City; physically healthy; voluntary participation in the project with signed informed consent.\n\nExclusion Criteria:\n\n* Individuals ever diagnosed with malignant tumors or cardiovascular and cerebrovascular diseases by physicians or other health professionals; those with unstable vital signs or an expected survival time of less than 3 months; participants with incomplete basic information, and those unable to cooperate with subsequent follow-up.","ALL","30 Years","80 Years",{"count":60,"type":61},4500,"ESTIMATED","10 Years","OBSERVATIONAL","1. To establish a standardized, normalized and scientific joint screening and follow-up management system for chronic disease multimorbidity in Lishui City, and early identify common risk factors of major chronic diseases such as cardiovascular and cerebrovascular diseases and tumors.\n2. To carry out targeted intervention and long-term follow-up for high-risk populations, reduce the incidence risk of major chronic diseases in the target population, improve residents' health status and grassroots comprehensive prevention and treatment capacity of chronic diseases, and provide scientific evidence and practical support for the construction of Healthy Lishui.",[66,67,68],"Ischemic Stroke","Chronic Disease","Cardiovascular",[70,71,72],"acute ischemic stroke","carotid artery stenosis","Hepatic fibrosis","2026-05-12",{"date":75,"type":76},"2026-05-18","ACTUAL",{"date":75,"type":61},{"date":79,"type":61},"2036-05-31",{"name":5,"class":6},1]