[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639591":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":10,"responsibleParty":31,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":10,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":53,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":10},{"fullName":5,"class":6},"Tel Aviv University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Adults",null,"Healthy adult participants undergoing repeated measurements of resting metabolic rate (RMR) three times per week over a 12-week period under standardized conditions. No intervention is applied.",[13],"Other: Repeated Measurement of Resting Metabolic Rate",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Repeated Measurement of Resting Metabolic Rate","Repeated assessment of resting metabolic rate under standardized conditions; no intervention is administered.",[9],[20],{"name":21,"affiliation":5,"role":22},"Yftach Prof. Gepner","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+972 50-682-8501","gepner@tauex.tau.ac.il",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":10},"Lien Bruck","+972 587487431",{"type":22,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Gepner Yftach","Principal Investigator - Professor","100639591","within-individual-variability-of-resting-metabolic-rate-over-12-weeks-100639591",false,"NCT07628764","Within-Individual Variability of Resting Metabolic Rate Over 12 Weeks","Within-Individual Variability of Resting Metabolic Rate Assessed Repeatedly Over 12 Weeks Using Whole-Room Calorimetry","Inclusion Criteria:\n\n* Adults aged 18-65 years\n* Clinically healthy individuals\n* Stable body weight (±2 kg) over the past 3 months\n* Ability and willingness to attend morning measurements three times per week for 12 weeks\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Known uncontrolled endocrine or metabolic disease\n* Use of medications known to significantly affect resting metabolic rate (e.g., systemic corticosteroids, unstable thyroid hormone therapy)\n* Acute illness within 14 days prior to enrollment\n* Pregnancy or lactation\n* Any medical condition that, in the opinion of the investigators, may interfere with safe participation",true,"ALL","18 Years","65 Years",{"count":46,"type":47},30,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to characterize within-individual variability in resting metabolic rate (RMR) over a 12-week period using high-frequency repeated measurements under standardized conditions. Participants will undergo RMR assessments three times per week using whole-room indirect calorimetry.\n\nThe study will quantify the magnitude of physiological variability in RMR, distinguish true biological variation from measurement error, and estimate the minimal detectable change required to identify meaningful metabolic adaptations.",[51,52],"Resting Metabolic Rate","Energy Metabolism",[51,54,55,56,57],"Energy Expenditure","Metabolism","Indirect Calorimetry","Variability","NOT_YET_RECRUITING","2026-06-01",{"date":61,"type":62},"2026-06-05","ACTUAL",{"date":64,"type":47},"2026-07",{"date":66,"type":47},"2027-12",{"name":5,"class":6}]