[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100532729":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":45,"centralContacts":50,"locations":60,"responsibleParty":81,"collaborators":84,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":102,"minAge":103,"maxAge":32,"enrollmentInfo":104,"targetDuration":32,"studyType":107,"phases":108,"briefSummary":110,"conditions":111,"keywords":32,"overallStatus":63,"whyStopped":32,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":125},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,16,22],{"label":9,"type":10,"description":11,"interventionNames":12},"WE RISE Intervention","EXPERIMENTAL","Participants will undergo WE RISE intervention: twice a week for 8 week combination delivery of acceptance and commitment therapy + exercise + social suppot.",[13,14,15],"Behavioral: Acceptance and Commitment Therapy (ACT)","Behavioral: Body weight circuit training","Behavioral: Empathetic social support",{"label":17,"type":18,"description":19,"interventionNames":20},"Control","ACTIVE_COMPARATOR","Participants will receive standard of care which would be referrals to local opportunites for therapy, exercise and social support.",[21],"Other: Control - list of resources",{"label":23,"type":10,"description":24,"interventionNames":25},"Observational","Observational study of participants undergoing WE RISE adapted for sustainability.",[13,14,15],[27,33,37,41],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Acceptance and Commitment Therapy (ACT)","Participants will undergo ACT in combination with exercise and social support.",[23,9],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Body weight circuit training","Participants will learn and undergo body weight circuit training in combination with ACT and social support.",[23,9],{"type":28,"name":38,"description":39,"armGroupLabels":40,"otherNames":32},"Empathetic social support","Study participants will participate in empathetic social support",[23,9],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":32},"Control - list of resources","A local list of resources to access exercise, therapy and social support will be provided.",[17],[46],{"name":47,"affiliation":48,"role":49},"Maile Karris, MD","UCSD","PRINCIPAL_INVESTIGATOR",[51,56],{"name":52,"role":53,"phone":54,"phoneExt":32,"email":55},"Liliana Harkness","CONTACT","619-543-4753","lir003@health.ucsd.edu",{"name":57,"role":53,"phone":58,"phoneExt":32,"email":59},"Helene Le","619-543-3116","helenele@health.ucsd.edu",[61],{"facility":62,"status":63,"city":64,"state":65,"zip":66,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"UC San Diego AntiViral Research Center (AVRC)","RECRUITING","San Diego","California","92103","United States","US",{"type":70,"coordinates":71},"Point",[72,73],-117.16472,32.71571,{"lat":73,"lon":72},[76,77],{"name":52,"role":53,"phone":54,"phoneExt":32,"email":55},{"name":78,"role":53,"phone":79,"phoneExt":32,"email":80},"Emily Kvitek","619-543-8080","ekvitek@health.ucsd.edu",{"type":49,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Maile Young Karris","Associate Professor",[85,87,89,91],{"name":86,"class":6},"Christie's Place",{"name":88,"class":6},"By His Stripes Wellness Center",{"name":90,"class":6},"Sister Love",{"name":92,"class":93},"APLA Health","UNKNOWN","100532729","women-focused-encounters-for-resilience-independence-strength-and-eudaimonia-100532729",false,"NCT06216600","Women Focused Encounters for Resilience Independence Strength and Eudaimonia","WE RISE","Inclusion Criteria:\n\n1. Is a woman\n2. Able to read and understand English\n3. Able to participate in a low intensity exercise program\n4. HIV-seropositive\n5. At risk substance use (any illegal or unprescribed drug), tobacco, marijuana or alcohol use (four or more drinks in one day or 8 or more in one week).\n6. Reports missing more ART doses than previous months, or \\> 5 in a month, or has a detectable HIV viral load\n7. Experienced interpersonal violence\n8. Able and willing to provide informed consent\n\nExclusion Criteria:\n\n1. Unwilling to participate in video record sessions (used to evaluate the quality of the intervention)\n2. Enrolled in hospice\n3. Not willing or not able to comply with study advisory board group participation agreement.",true,"FEMALE","18 Years",{"count":105,"type":106},300,"ESTIMATED","INTERVENTIONAL",[109],"NA","The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance (ab)use, violence, and AIDS\u002FHIV (SAVA) to improve medication adherence for women living with HIV (WLWH). This intervention will be implemented by community based organizations that focus on WLWH across four counties. The main question it aims to answer are:\n\n* Will peer provision of ACT, exercise, and social support improve medication adherence for WLWH?\n* Will community based organizations be able to sustain the intervention after research is completed, and what changes will need to be made to sustain the intervention.",[112,113,114,115],"HIV Infections","Substance Use","Trauma","Medication Adherence","2026-04-27",{"date":118,"type":119},"2026-05-01","ACTUAL",{"date":121,"type":119},"2024-09-19",{"date":123,"type":106},"2028-05-31",{"name":5,"class":6},1]