[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100478437":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":64,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":25,"eligibilityCriteria":76,"healthyVolunteers":73,"sex":77,"minAge":78,"maxAge":25,"enrollmentInfo":79,"targetDuration":25,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Arm","PLACEBO_COMPARATOR","Women assigned to the control arm (n=180) will receive one 60-minute group session facilitated by the licensed clinical therapist (LCT) on self-care and well-being as it relates to HIV, interpersonal violence, trauma, adverse mental health, and substance use. During this session, women will be provided with resources to HIV care, interpersonal violence, trauma, mental health, and substance use, through a static website created for Women SHINE. The content will include: 1) names and locations of clinics and organizations, services provided, and contact information; 2) links to support websites and hotlines and 3) testimonials from WLHA.",[13],"Behavioral: Control",{"label":15,"type":16,"description":17,"interventionNames":18},"Women SHINE","EXPERIMENTAL","Women SHINE consists of a four-month intervention that includes video-based one-on-one peer navigation and 7 weekly psycho-education support group sessions co-facilitated by a licensed clinical therapist (LCT) and peer navigator (PN). 180 women will be enrolled in the Women SHINE intervention and will remain in their assigned psycho-education support group sessions with the same members over the course of the intervention.",[19],"Behavioral: Women SHINE",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Minimum of nine weekly one-on-one peer navigation sessions and 7 weekly psychoeducation support group sessions.",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Control","Single group session and access to website",[9],[31],{"name":32,"affiliation":5,"role":33},"Jamila K Stockman, PhD, MPH","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Cassandra Cyr, MPH","CONTACT","(858) 534-7979","clcyr@health.ucsd.edu",{"name":32,"role":37,"phone":41,"phoneExt":25,"email":42},"(858) 822-4652","jstockman@health.ucsd.edu",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"The Regents of the Univ. of Calif., U.C. San Diego","RECRUITING","La Jolla","California","92093","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-117.2742,32.84727,{"lat":56,"lon":55},[59,63],{"name":60,"role":37,"phone":61,"phoneExt":25,"email":62},"Jamila K Stockman, PhD","8588224652","jstockman@ucsd.edu",{"name":60,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":33,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Jamila K. Stockman","Professor and Vice Chief, Global Public Health Section",[68],{"name":69,"class":70},"National Institute of Mental Health (NIMH)","NIH","100478437","women-shine-addressing-syndemics-and-hiv-among-women-through-tech-based-peer-engagement-100478437",false,"NCT05509959","Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement","Inclusion Criteria:\n\n* Cisgender female\n* Diagnosis of HIV by a physician, healthcare provider, or community health worker\n* Aged 18 years or older\n* Speaking and reading English or Spanish\n* Adulthood experiences of interpersonal violence\n* Currently prescribed ART\n* Self-report of \\\u003C90% past-month ART adherence\n* Not currently participating in another adherence intervention\n* Access to an internet browser\n\nExclusion Criteria:\n\n* Unwillingness to participate in the intervention\n* Transgender female\n* No diagnosis of HIV by a physician, healthcare provider, or community health worker\n* Aged less than 18 years\n* Not speaking and reading English or Spanish\n* Not currently prescribed ART\n* Self-report of \\>= 90% past-month ART adherence\n* Currently participating in another adherence intervention\n* No access to an internet browser\n* Cognitive impairment limiting the ability to provide informed consent\n* Experiencing only childhood experiences of interpersonal violence\n* Inability to safely participate in the study based on secondary screener","FEMALE","18 Years",{"count":80,"type":81},360,"ESTIMATED","INTERVENTIONAL",[84],"NA","A two-arm RCT will be conducted to test the efficacy of Women SHINE, a web-based trauma-informed peer navigation-social support intervention (Figure 2). A total of 360 women living with HIV\u002FAIDS (WLHA) with a history of adulthood interpersonal violence who have been prescribed ART but are non-adherent (\\\u003C 90% ART adherent in the last 4 weeks) will be enrolled in the study. WLHA will be randomized (1:1) into one of the following conditions: 1) Women SHINE intervention arm (n=180) or 2) Control arm (n=180). The Women SHINE intervention arm will receive a four-month intervention including peer navigator (PN) one-on-one sessions, phone\u002Ftext-based check-ins, 7 psychoeducation weekly support group sessions (120 mins.) co-facilitated by a licensed therapist and PN, and access to a static website with resources for HIV care, interpersonal violence, trauma, mental health, and substance use. The control arm will receive one group session (60 mins.) on self-care and well-being and access to the aforementioned website with resources. Women will complete a video-based survey and mailed hair sample self-collection at baseline, 4-, 8-, and 12-months post-randomization, to evaluate improvements in ART adherence (Aim 1), emotion regulation, and PTSD symptoms (Aim 2). Investigators will examine the mediating effect of individual (retention in HIV care, coping self-efficacy, social support, ancillary support services use) and socio-structural (stigma, medical mistrust) mechanisms of change on the efficacy of Women SHINE (Aim 3).",[87],"HIV\u002FAIDS",[89,90],"HIV Care Continuum","Psychoeducation","2025-10-15",{"date":93,"type":94},"2025-10-20","ACTUAL",{"date":96,"type":94},"2022-11-15",{"date":98,"type":81},"2026-09-01",{"name":5,"class":6},1]