[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595833":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":57,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":10,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Vastra Gotaland Region","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AHG (Acute Hemorrhagic Cystitis Group):",null,"Patients with acute onset macroscopic hematuria with lower urinary tract symptoms such as dysuria, frequency, and urgency of less than one week's duration.",[13],"Procedure: investigation setting (cystoscopy + CTU + cytology)",{"label":15,"type":10,"description":16,"interventionNames":17},"non AHG (non-Acute Hemorrhagic Cystitis Group):","Patients with atypical clinical presentation such as:\n\nChronic irritative symptoms \\>4 weeks. Recurrent UTI (≥2 episodes in 6 months or ≥3 episodes per year). Febrile UTI. Absence of irritative symptoms.",[18],"Procedure: Cystoscopy - CTU - cytology (if needed)",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","investigation setting (cystoscopy + CTU + cytology)","Observational study. All patients in this group undergo standard diagnostic evaluation including cystoscopy, CT urography, and urine cytology (if clinically indicated), performed during initial assessment for acute macroscopic hematuria.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Cystoscopy - CTU - cytology (if needed)","All patients in this group undergo standard diagnostic evaluation including cystoscopy, CT urography, and urine cytology (if clinically indicated), performed during initial assessment for atypical or chronic presentations of macroscopic hematuria.",[15],[30],{"name":31,"affiliation":32,"role":33},"Suleiman Abuhasanein","Department of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Suleiman Abuhasanein, PhD","CONTACT","0104353572","suleiman.abuhasanein@gu.se",[41],{"facility":42,"status":43,"city":44,"state":10,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Uddevalla Hospital","RECRUITING","Uddevalla","45 198","Sweden","SE",{"type":49,"coordinates":50},"Point",[51,52],11.9424,58.34784,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":38,"phoneExt":10,"email":39},"Abuhasanein",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100595833","women-with-isolated-acute-cystitis-and-macroscopic-hematuria-is-further-investigation-needed-100595833",false,"NCT07037589","Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?","Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed? A Prospective Multicenter Study. BLUSH Trial","BLUSH","Inclusion Criteria:\n\n1. Women ≥50 years of age.\n2. Macroscopic hematuria.\n3. Presenting for evaluation within the SCP for macroscopic hematuria.\n4. Ability to provide informed consent.\n\nExclusion Criteria:\n\n1. Prior diagnosis of bladder cancer, renal cancer, or upper tract urothelial carcinoma (UTUC).\n2. Cognitive impairment preventing informed consent.\n3. Ongoing or recent treatment for urological malignancy.\n4. Serious comorbidities affecting participation or safety.\n5. Pregnant women.",true,"FEMALE","18 Years","110 Years",{"count":72,"type":73},300,"ESTIMATED","OBSERVATIONAL","This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.",[77,78,79,80,81],"Hematuria","Acute Cystitis With Hematuria","Bladder Cancer","Urothelial Carcinoma","Renal Cancer","2025-11-17",{"date":84,"type":85},"2025-11-21","ACTUAL",{"date":87,"type":85},"2025-10-13",{"date":89,"type":73},"2027-08-30",{"name":5,"class":6},1]