[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621610":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":48,"centralContacts":53,"locations":59,"responsibleParty":75,"collaborators":25,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":25,"enrollmentInfo":87,"targetDuration":25,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":98,"whyStopped":25,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"French Cardiology Society","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Participants will undergo examination before the race, during the race, at the arrival of the race, and 9 days after the race.",[13,14,15,16,17,18],"Procedure: Echocardiography","Procedure: Arterial ultrasound","Biological: Blood sampling","Behavioral: Scales and questionnaire","Procedure: Vital signs","Biological: Urinary test",[20,26,30,35,40,44],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Echocardiography","6 transthoracic echocardiography will be performed: 1 before the race, 3 during the race (refreshment station), 1 at the end of the race, 1 at the follow up visit 9 days after the race. It is not possible to specify the intervention time, as this depends on the participants' running pace.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Arterial ultrasound","6 ultrasound of the carotid and femoral arteries will be performed: 1 before the race, 3 during the race (refreshment station), 1 at the end of the race, 1 at the follow up visit 9 days after the race. It is not possible to specify the intervention time, as this depends on the participants' running pace.",[9],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":25},"BIOLOGICAL","Blood sampling","6 blood sampling (2 milliliters) will be performed: 1 before the race, 3 during the race (refreshment station), 1 at the end of the race, 1 at the follow up visit 9 days after the race. It is not possible to specify the intervention time, as this depends on the participants' running pace.",[9],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":25},"BEHAVIORAL","Scales and questionnaire","Before the race, during the race (refreshment station), and at the end of the race participant will be asked to complete the study questionnaire and scales. It is not possible to specify the intervention time, as this depends on the participants' running pace.",[9],{"type":21,"name":41,"description":42,"armGroupLabels":43,"otherNames":25},"Vital signs","6 measurements of blood pressure, heart rate, respiratory rate, pulse oxygen saturation, and muscle oxygen saturation will then be taken: 1 before the race, 3 during the race (refreshment station), 1 at the end of the race, 1 at the follow up visit 9 days after the race. It is not possible to specify the intervention time, as this depends on the participants' running pace.",[9],{"type":31,"name":45,"description":46,"armGroupLabels":47,"otherNames":25},"Urinary test","Pregnancy test will be performed before the race.",[9],[49],{"name":50,"affiliation":51,"role":52},"Romain JOUFFROY, MD","CHU d'Orléans","PRINCIPAL_INVESTIGATOR",[54],{"name":55,"role":56,"phone":57,"phoneExt":25,"email":58},"Tessa BERGOT, MSc","CONTACT","+33144907033","tessa.bergot@sfcariod.fr",[60],{"facility":61,"status":25,"city":62,"state":25,"zip":25,"country":63,"countryCode":64,"cosmosGeoPoint":65,"geoPoint":70,"contacts":71},"Hôpital Henri Mondor, APHP","Créteil","France","FR",{"type":66,"coordinates":67},"Point",[68,69],2.46569,48.79266,{"lat":69,"lon":68},[72],{"name":73,"role":56,"phone":25,"phoneExt":25,"email":74},"Thomas D'HUMIERES, MD","thomas.d'humieres@aphp.fr",{"type":76,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100621610","womens-heart-impact-of-ultra-endurance-and-hormonal-profile-on-cardiac-and-systemic-inflammatory-parameters-in-female-runners-100621610",false,"NCT07372859","Women's Heart: Impact of Ultra-endurance and Hormonal Profile on Cardiac and Systemic Inflammatory Parameters in Female Runners","COEUR","Inclusion Criteria:\n\n* Must have a Global Positioning System watch during the race;\n* Must participate in one of the following races:\n\n  * \"Ecotrail de Paris Ile France©\" (=a trail running race in the Paris region, it is not possible to translate; it is a registered trademark) 80 kilometers;\n  * Or \"la 6000D©\" 69 kilometers;\n* Must comply with the race regulations:\n\n  * Medical certificate stating no contraindications to competitive running, dated less than 12 months prior to the race;\n  * Or a valid sports license on the day of the race.\n* Must agree to participate in the study, sign the consent form, and allow the sponsor to use their data for the purposes of this study.\n\nExclusion Criteria:\n\n* Refusal or linguistic or mental incapacity to sign the informed consent form;\n* Person under guardianship (conservatorship, curators, or legal protection) or deprived of liberty;\n* Person not affiliated with a social security scheme;\n* Pregnant woman;\n* Person participating in a drug study;\n* Women with a medical history (chronic lung disease, heart disease, pharmacologically treated hypertension) or with a known significant chronic inflammatory disease at the time of the enrollment visit;\n* Person who has already participated in this study in a previous race.",true,"FEMALE","18 Years",{"count":88,"type":89},120,"ESTIMATED","INTERVENTIONAL",[92],"NA","The goal of this clinical trial is to describe the cardiac and systemic inflammatory adaptations specific to women practicing ultra-endurance sports.\n\nThe objectives are to:\n\n* Improve the understanding of cardiac and systemic inflammatory adaptations specific to women participating in ultra-endurance sports.\n* Assess the relationship between observed cardiac and systemic inflammatory alterations and the relative levels of estrogen, testosterone, and progesterone.\n* Describe the vascular adaptations specific to women participating in ultra-endurance sports.\n* Examine the influence of defense mechanisms on the emotional dynamics observed during and after an ultra-endurance race.",[95],"Healthy Volunteer",[97],"ultra endurance","NOT_YET_RECRUITING","2026-01-23",{"date":101,"type":102},"2026-01-28","ACTUAL",{"date":104,"type":89},"2026-03-22",{"date":106,"type":89},"2026-09-30",{"name":5,"class":6},1]