[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613577":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":30,"responsibleParty":51,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":33,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Daily Nouri","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention: Dietary Supplement Capsule","EXPERIMENTAL","Hormone Balance Probiotic blend",[13],"Dietary Supplement: Probiotic Blend Capsule",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo: Capsule","PLACEBO_COMPARATOR","Identical capsule containing inactive ingredients",[19],"Dietary Supplement: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Probiotic Blend Capsule","Hormone Balance Probiotic Blend",[9],null,{"type":22,"name":28,"description":28,"armGroupLabels":29,"otherNames":26},"Placebo",[15],[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Alethios, Inc.","RECRUITING","San Francisco","California","94109","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-122.41942,37.77493,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":49,"phoneExt":26,"email":50},"Alethios","CONTACT","(650) 206-8006","support@alethios.com",{"type":52,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100613577","womens-hormonal-and-metabolic-wellbeing-study-100613577",false,"NCT07268404","Women's Hormonal and Metabolic Wellbeing Study","A 12-Week Virtual, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Effects of Daily Nouri Hormone Balance Probiotic on Metabolic, Inflammatory, and Symptom Outcomes in Women","Inclusion Criteria:\n\n* Self-reported irregular menstrual cycles, defined as one or more of the following:\n\n  * Cycle length typically \\>35 days OR \\\u003C21 days\n  * Fewer than 9 menstrual periods in the past year\n  * Unpredictable cycle timing (varies by \\>7 days month-to-month)\n  * Irregular cycles present for ≥6 months\n* One or more of the following hormonal balance concerns: skin, unwanted hair growth, hair thinning, weight concerns)\n* Self-reported emotional symptoms that fluctuate with menstrual cycle, including:\n\n  * Mood swings or irritability\n  * Feelings of stress or tension\n  * Low mood or feeling down\n  * Difficulty with emotional regulation\n* Not currently using hormonal therapies, metformin, GLP-1 receptor agonists, or anti-androgens.\n* If taking supplements for menstrual\u002Fhormonal support: willing to discontinue for 2-week washout before baseline\n* Weight stable (+ 5 pounds) for the past 2 months, not planning to start a new diet, exercise program, or medications during study\n* Able to provide electronic informed consent.\n* Willing to complete online surveys and at-home DBS sample collection.\n* Negative home pregnancy test at baseline.\n* Access to a computer or smartphone and reliable internet connection.",true,"FEMALE","18 Years","45 Years",{"count":65,"type":66},60,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.\n\nParticipants will:\n\n* Take the probiotic blend or placebo every day for 12 weeks\n* Complete virtual assessments and report symptoms throughout the study",[72],"Metabolic Health",[74,75,76,77],"dietary supplement","quality of life","women's health","hormone balance","2025-12-12",{"date":80,"type":81},"2025-12-19","ACTUAL",{"date":83,"type":66},"2025-12",{"date":85,"type":66},"2026-12",{"name":5,"class":6},1]