[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630512":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":49,"collaborators":20,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":20,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":20,"enrollmentInfo":62,"targetDuration":20,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":20,"overallStatus":71,"whyStopped":20,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Woundsome-Guided Revascularization","EXPERIMENTAL","Revascularization strategy directed toward restoring arterial blood flow specifically to the wound location (woundsome). Target vessel selection is based on the artery most likely to provide direct perfusion to the wound area, considering anatomical variations, collateral circulation, and pedal arch patency, rather than relying solely on the traditional angiosome-based approach.",[13],"Procedure: Revascularization by Percutaneous Transluminal Angioplasty",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Revascularization by Percutaneous Transluminal Angioplasty","Endovascular revascularization is performed under fluoroscopic guidance using femoral artery access. Balloon angioplasty targets infrapopliteal vessels supplying direct blood flow to the wound. Post-procedure angiography assesses wound perfusion (woundsome), and patients are classified as having successful or unsuccessful woundsome revascularization based on contrast opacification around the wound.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Mahmoud Ismael Ahmed Saleh, PHD","Vascular and Endovascular surgery department Assiut University","STUDY_DIRECTOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Andrew Wageeh Latif Resident Doctor, Master's degree","CONTACT","+201149193361","andrewwageeh49@gmail.com",[33],{"facility":34,"status":20,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Vascular and Endovascular surgery department Assiut university","Asyut","Asyut Governorate","71511","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.18368,27.18096,{"lat":44,"lon":43},[47],{"name":48,"role":29,"phone":30,"phoneExt":20,"email":31},"Andrew Wageeh Resident doctor, Master's degree",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Andrew Wageeh Latif","Resident Doctor","100630512","woundsome-revascularization-in-chronic-limb-threatening-ischemia-100630512",false,"NCT07488637","Woundsome Revascularization in Chronic Limb-Threatening Ischemia","Impact of Woundsome Revascularization on the Outcomes of Endovascular Intervention in Patients With Chronic Limb-Threatening Ischemia","Inclusion criteria:\n\n1\\. Patients with chronic limb-threatening ischemia (CLTI) with tissue loss (Rutherford Class 5 or 6, or WIFI stage 2-4) 2. Patients with infrapopliteal arterial occlusions requiring revascularization\n\n\\-\n\nExclusion Criteria:\n\n1. Patients with unsalvageable limbs\n2. Patients with acute limb ischemia (ALI)\n3. Patients with non-atherosclerotic diseases such as vasculitis, including:\n\n   Large vessel vasculitis (e.g., giant cell arteritis, Takayasu arteritis) Medium vessel vasculitis (e.g., polyarteritis nodosa, Kawasaki disease) Small vessel vasculitis (e.g., granulomatosis with polyangiitis, microscopic polyangiitis) Other types (e.g., Behçet's disease, Buerger's disease)\n4. Patients with contraindications to contrast medium\n5. Patients with aortoiliac or femoropopliteal occlusive disease","ALL","18 Years",{"count":63,"type":64},50,"ESTIMATED","INTERVENTIONAL",[67],"NA","Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease and remains a major health problem. Although the angiosome concept was introduced to guide revascularization by restoring direct blood flow to the affected tissue, its usefulness is limited by anatomical variations, collateral circulation, and wounds involving multiple territories. The emerging \"woundsome\" concept focuses instead on improving arterial perfusion directly to the wound area, recognizing that both direct revascularization and",[70],"Chronic Limb-Threatening Ischemia","NOT_YET_RECRUITING","2026-03-27",{"date":74,"type":75},"2026-04-01","ACTUAL",{"date":74,"type":64},{"date":78,"type":64},"2027-10-01",{"name":5,"class":6},1]