[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611435":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":51,"centralContacts":55,"locations":64,"responsibleParty":79,"collaborators":30,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":30,"eligibilityCriteria":88,"healthyVolunteers":84,"sex":89,"minAge":90,"maxAge":30,"enrollmentInfo":91,"targetDuration":30,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":105,"whyStopped":30,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Participants assigned to the intervention group will receive a 3-month behavioral intervention comprising a 4-week xylitol gum aligned with 12 weeks of instant reminder message support.",[13,14,15,16,17,18],"Behavioral: Brief smoking cessation advice","Behavioral: Warning leaflet","Behavioral: Self-help smoking cessation booklet","Behavioral: 4-week xylitol gum intervention","Behavioral: Instructional leaflet","Behavioral: 12-week instant message support",{"label":20,"type":21,"description":22,"interventionNames":23},"Control group","ACTIVE_COMPARATOR","Participants in the control group will receive brief SC advice and a SC information booklet at baseline, which had been routinely used in our previous trials.",[13,14,15],[25,31,35,39,43,47],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","Brief smoking cessation advice","Brief smoking cessation advice guided by the validated AWARD model (Assess, Warning, Advice, Refer, and Do-it-again).",[20,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Warning leaflet","The warning leaflet contains pictorial depictions of the adverse health effects of smoking.",[20,9],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Self-help smoking cessation booklet","The self-help smoking cessation booklet includes commonly used smoking cessation strategies.",[20,9],{"type":26,"name":40,"description":41,"armGroupLabels":42,"otherNames":30},"4-week xylitol gum intervention","Participants in the intervention group will receive 4 packs of xylitol gum (approximately US $2 per pack) at baseline and will be encouraged to use it when they experience cravings.",[9],{"type":26,"name":44,"description":45,"armGroupLabels":46,"otherNames":30},"Instructional leaflet","The instructional leaflet includes the potential benefits of xylitol gum for smoking cessation, recommended timing and dosage for use, and appropriate disposal of used gum.",[9],{"type":26,"name":48,"description":49,"armGroupLabels":50,"otherNames":30},"12-week instant message support","Approximately 24 reminder messages (two per week), developed based on the Love and Care Approach framework, will be delivered over the 12-week period to reinforce motivation and adherence.",[9],[52],{"name":53,"affiliation":5,"role":54},"Man Ping Wang, PhD","PRINCIPAL_INVESTIGATOR",[56,61],{"name":57,"role":58,"phone":59,"phoneExt":30,"email":60},"Mengyao Li, Mphil","CONTACT","+852 6851 8462","lmy0814@connect.hku.hk",{"name":53,"role":58,"phone":62,"phoneExt":30,"email":63},"+852 3917 6636","mpwang@hku.hk",[65],{"facility":66,"status":30,"city":67,"state":30,"zip":30,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":75},"School of Nursing, The University of Hong Kong","Hong Kong","HK",{"type":70,"coordinates":71},"Point",[72,73],114.17469,22.27832,{"lat":73,"lon":72},[76],{"name":77,"role":58,"phone":78,"phoneExt":30,"email":60},"Mengyao Li","68518462",{"type":54,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Prof. Wang Man-Ping","Professor","100611435","xylitol-gum-for-promoting-smoking-cessation-100611435",false,"NCT07240545","Xylitol Gum for Promoting Smoking Cessation","The Effectiveness of Chewing Gum for Reducing Cigarette Consumption and Promoting Smoking Cessation: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Residents of Hong Kong aged 18 or above who smoke at least 1 cigarette per day over the past 3 months\n* Have the habit of chewing gum or are willing to use chewing gum\n* Can communicate in Cantonese (including reading Chinese)\n* Express an intention to quit or reduce smoking\n* Capable of using instant messaging tools (e.g., WhatsApp, WeChat) for communication\n\nExclusion Criteria:\n\n* Have communication barriers (either physical or cognitive)\n* Currently participating in other smoking cessation programs or services","ALL","18 Years",{"count":92,"type":93},134,"ESTIMATED","INTERVENTIONAL",[96],"NA","The goal of this clinical trial is to learn if 4-week xylitol gum intervention works to promote smoking cessation in daily smokers. It will also learn about the feasibility and acceptability of using xylitol gum. The main questions it aims to answer are:\n\n（1）Does xylitol gum help to reduce cigarette consumption and promote smoking cessation?\n\nResearchers will compare 4-week xylitol gum intervention to the brief advice to see if xylitol gum works to promote smoking cessation.\n\nParticipants in the intervention group will receive a 3-month behavioral intervention comprising a 4-week xylitol gum aligned with 12 weeks of instant reminder message support.",[99,100],"Smoking Cessation","Health Promotion",[102,103,104],"Xylitol gum","Smoking cessation","Hybrid type 1 effectiveness-implementation design","NOT_YET_RECRUITING","2025-11-16",{"date":108,"type":109},"2025-11-21","ACTUAL",{"date":111,"type":93},"2025-11-24",{"date":113,"type":93},"2026-09-30",{"name":5,"class":6},1]