[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595412":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":30,"responsibleParty":97,"collaborators":101,"id":125,"slug":126,"hasResults":127,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":10,"eligibilityCriteria":131,"healthyVolunteers":127,"sex":132,"minAge":133,"maxAge":134,"enrollmentInfo":135,"targetDuration":10,"studyType":138,"phases":10,"briefSummary":139,"conditions":140,"keywords":10,"overallStatus":142,"whyStopped":10,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":152},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Exposed group",null,"People receiving exposure factors:In addition to the basic treatment and non-Yiqi Jiangzhuo Huoxue Tongluo Chinese patent medicine(except for Niaoduqing Granules, Shenshuaining Tablets\u002FCapsules,Qizhi Capsules,Qizhi Yishen Capsules and other Chinese patent medicine),the exposure factors were treated with Shenqi Decoction(composed of Astragalus,Salvia miltiorrhiza,Leech,Rhubarb,Epimedium,Motherwort)as the representative of Yiqi Jiangzhuo Huoxue Tongluo Chinese medicine prescription treatment,and did not receive other traditional Chinese medicine treatment measures for urinary protein or renal insufficiency.The definition of basic treatment is:standardized diet,exercise,hypoglycemic,antihypertensive,lipid-lowering and other basic treatment measures,appropriate doses of angiotensin converting enzyme inhibitors(ACEI)\u002Fangiotensin receptor blockers(ARB),sodium-glucose co-transporter 2 inhibitors(SGLT2i),salt hormone receptor antagonists(MRA) and other drugs with clear renal protective effect",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-exposed group","Diabetic kidney disease patients who did not receive exposure factors.",[16],{"name":17,"affiliation":18,"role":19},"HongFang Liu","Dongzhimen Hospital","STUDY_DIRECTOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Qingqing Liu","CONTACT","+8615811362511","125982343@qq.com",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Fengyi Cai","+8618810623691","cfy201802@163.com",[31,45,55,69,83],{"facility":32,"status":10,"city":33,"state":34,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Dongzhimen Hospital of BeijingUniversity of Chinese Medicine","Beijing","Beijing Municipality","China","CN",{"type":38,"coordinates":39},"Point",[40,41],116.39723,39.9075,{"lat":41,"lon":40},[44],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"facility":46,"status":10,"city":33,"state":34,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":47,"geoPoint":49,"contacts":50},"Guang'anmen Hospital，China Academy of Chinese Medical Sciencescancel",{"type":38,"coordinates":48},[40,41],{"lat":41,"lon":40},[51],{"name":52,"role":23,"phone":53,"phoneExt":10,"email":54},"Shen Li","+8613681116668","Lishen58173@163.com",{"facility":56,"status":10,"city":57,"state":58,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"The First Affiliated Hospital of Sun Yat-sen University","Guangzhou","Guangdong",{"type":38,"coordinates":60},[61,62],113.25,23.11667,{"lat":62,"lon":61},[65],{"name":66,"role":23,"phone":67,"phoneExt":10,"email":68},"Wei Chen","+8613924150966","chenwei99@mail.sysu.edu.cn",{"facility":70,"status":10,"city":71,"state":72,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"The Affiliated Hospital to ChangChun University of Chinese Medicinecancel","Changchun","Jilin",{"type":38,"coordinates":74},[75,76],125.32278,43.88,{"lat":76,"lon":75},[79],{"name":80,"role":23,"phone":81,"phoneExt":10,"email":82},"Jia Mi","+8613630558296","mijia8201@126.com",{"facility":84,"status":10,"city":85,"state":86,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Tianjin Medical University Chu Hsien-I Memorial Hospital","Tianjin","Tianjin Municipality",{"type":38,"coordinates":88},[89,90],117.17667,39.14222,{"lat":90,"lon":89},[93],{"name":94,"role":23,"phone":95,"phoneExt":10,"email":96},"Baocheng Chang","+8618622051556","changbc1970@126.com",{"type":98,"investigatorFullName":99,"investigatorTitle":100,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Liu Hongfang","Chief Physician",[102,104,106,108,110,113,115,117,119,121,123],{"name":103,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences",{"name":105,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":107,"class":6},"Tianjin Medical University",{"name":109,"class":6},"Changchun University of Chinese Medicine",{"name":111,"class":112},"EFONG PHARMRCEUTICRL","UNKNOWN",{"name":114,"class":112},"Xinxiang Central Hospital of Henan province",{"name":116,"class":6},"Xiamen Hospital of Traditional Chinese Medicine",{"name":118,"class":6},"Affiliated Hospital of Liaoning University of Traditional Chinese Medicine",{"name":120,"class":6},"Beijing Tiantan Hospital",{"name":122,"class":6},"Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine",{"name":124,"class":112},"Hubei Zhongshan Hospital Affiliated to Wuhan University","100595412","yiqijiangzhuohuoxuetongluo-method-to-delay-the-occurrence-of-end-stage-renal-disease-in-diabetic-kidney-disease--study1-100595412",false,"NCT07032116","YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study1","Evidence-based Evaluation of Yiqi Jiangzhuo Huoxue Tongluo Method in Delaying the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study 1","Inclusion Criteria:\n\n* 1 in line with Western medicine diagnostic criteria for type 2 diabetic kidney disease ;\n* 2 18-80 years old, regardless of gender ;\n* 3 eGFR \\> 15ml \u002F ( min · 1.73m2 ) ; the eGFR was calculated according to the chronic kidney disease epidemiology collaboration equation ( CKD-EPI ).\n* 4 In line with the diagnostic criteria of qi deficiency and collateral stasis syndrome in traditional Chinese medicine ;\n* 5glycosylated hemoglobin ( HbA1c ) between 7-10 % ;\n* 6 blood pressure ≤ 160 \u002F 100mmHg ;\n* 7 to sign the informed consent ;\n\nExclusion Criteria:\n\n* 1 combined with other clear renal diseases, such as polycystic kidney disease, glomerulonephritis, renal tumor, etc. ;\n* 2 patients with a history of recurrent genitourinary tract infection ;\n* 3 combined with cardiovascular and cerebrovascular, digestive, respiratory, urinary, immune system serious diseases or mental diseases ;\n* 4 currently in pregnancy, lactation, or pregnancy plan women ;\n* 5 Patients with type 1 diabetes.\n* 6 Tumor patients undergoing radiotherapy, chemotherapy or targeted therapy.","ALL","18 Years","80 Years",{"count":136,"type":137},4472,"ESTIMATED","OBSERVATIONAL","In order to reduce the clinical demand for kidney dialysis rate of Diabetic Kidney Disease（DKD） patients, a bidirectional cohort study of 4472 patients with DKD (Qi deficiency and collateral stasis syndrome) was carried out based on a preliminary DKD cohort of 13,000 patients. The exposure factor was supplementing and reducing the kidney turbidity-Huoxue Tongluo method represented by the addition and subversion of Shenzhuo prescription, and the incidence of end-stage renal disease was the main therapeutic index. Follow-up was conducted for 2 years",[141],"Diabetic Kidney Disease (DKD)","NOT_YET_RECRUITING","2025-06-13",{"date":145,"type":146},"2025-06-22","ACTUAL",{"date":148,"type":137},"2025-08-01",{"date":150,"type":137},"2028-07-31",{"name":99,"class":6},5]