[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595619":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":50,"responsibleParty":116,"collaborators":120,"id":131,"slug":132,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":44,"eligibilityCriteria":137,"healthyVolunteers":133,"sex":138,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":44,"studyType":144,"phases":145,"briefSummary":147,"conditions":148,"keywords":44,"overallStatus":150,"whyStopped":44,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":160},{"fullName":5,"class":6},"Dongzhimen Hospital, Beijing","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Shenzhuo Decoction","EXPERIMENTAL","The experimental group was given the traditional Chinese medicine prescription ' Shenzhuo Decoction ' ( composed of Astragalus membranaceus, Salvia miltiorrhiza, Leech, Raw Rhubarb, Epimedium, Motherwort ) + basic treatment ( including nutrition, lifestyle, hypoglycemic, hypotensive, lipid-lowering, control of other risk factors, etc. )",[13,14],"Drug: the traditional Chinese medicine prescription ' Shenzhuo Decoction '","Combination Product: basic treatment",{"label":16,"type":17,"description":18,"interventionNames":19},"basic treatment","ACTIVE_COMPARATOR","the control group was given basic treatment, a total of 1 year of drug intervention（including nutrition, lifestyle, hypoglycemic, hypotensive, lipid-lowering, control of other risk factors, etc.）",[14],[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","the traditional Chinese medicine prescription ' Shenzhuo Decoction '","The traditional Chinese medicine prescription ' Shenzhuo Decoction ' is composed of Astragalus membranaceus, Salvia miltiorrhiza, Leech, Raw Rhubarb, Epimedium, Motherwort. It is a traditional Chinese medicine prescription for the treatment of diabetic kidney disease, which was founded by Tong Xiaolin, an academician of the Chinese Academy of Sciences.",[9],[27],"Chinese medicine",{"type":29,"name":16,"description":30,"armGroupLabels":31,"otherNames":32},"COMBINATION_PRODUCT","Basic treatment includes six aspects : nutrition, lifestyle, hypoglycemic, hypotensive, lipid-lowering, and control of other risk factors, which are implemented in accordance with clinical standard treatment specifications.",[9,16],[33],"control group",[35],{"name":36,"affiliation":37,"role":38},"HongFang Liu","Dongzhimen Hospital","STUDY_DIRECTOR",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Qingqing Liu","CONTACT","+8615811362511",null,"125982343@qq.com",{"name":47,"role":42,"phone":48,"phoneExt":44,"email":49},"Fengyi Cai","+8618810623691","cfy201802@163.com",[51,64,74,88,102],{"facility":37,"status":44,"city":52,"state":53,"zip":44,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Beijing","Beijing Municipality","China","CN",{"type":57,"coordinates":58},"Point",[59,60],116.39723,39.9075,{"lat":60,"lon":59},[63],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},{"facility":65,"status":44,"city":52,"state":53,"zip":44,"country":54,"countryCode":55,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"Guang'anmen Hospital，China Academy of Chinese Medical Sciencescancel",{"type":57,"coordinates":67},[59,60],{"lat":60,"lon":59},[70],{"name":71,"role":42,"phone":72,"phoneExt":44,"email":73},"Shen Li","+8613681116668","Lishen58173@163.com",{"facility":75,"status":44,"city":76,"state":77,"zip":44,"country":54,"countryCode":55,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"The First Affiliated Hospital of Sun Yat-sen University","Guangzhou","Guangdong",{"type":57,"coordinates":79},[80,81],113.25,23.11667,{"lat":81,"lon":80},[84],{"name":85,"role":42,"phone":86,"phoneExt":44,"email":87},"Wei Chen","+8613924150966","chenwei99@mail.sysu.edu.cn",{"facility":89,"status":44,"city":90,"state":91,"zip":44,"country":54,"countryCode":55,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"The Affiliated Hospital to ChangChun University of Chinese Medicinecancel","Changchun","Jilin",{"type":57,"coordinates":93},[94,95],125.32278,43.88,{"lat":95,"lon":94},[98],{"name":99,"role":42,"phone":100,"phoneExt":44,"email":101},"Jia Mi","+8613630558296","mijia8201@126.com",{"facility":103,"status":44,"city":104,"state":105,"zip":44,"country":54,"countryCode":55,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Tianjin Medical University Chu Hsien-I Memorial Hospital","Tianjin","Tianjin Municipality",{"type":57,"coordinates":107},[108,109],117.17667,39.14222,{"lat":109,"lon":108},[112],{"name":113,"role":42,"phone":114,"phoneExt":44,"email":115},"Baocheng Chang","+8618622051556","changbc1970@126.com",{"type":117,"investigatorFullName":118,"investigatorTitle":119,"investigatorAffiliation":5,"oldNameTitle":44,"oldOrganization":44},"SPONSOR_INVESTIGATOR","Liu Hongfang","Chief Physician",[121,123,125,127,129],{"name":65,"class":122},"UNKNOWN",{"name":124,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":126,"class":6},"Tianjin Medical University",{"name":128,"class":6},"Affiliated Hospital of Changchun University of Chinese Medicine",{"name":130,"class":122},"EFONG PHARMRCEUTICRL","100595619","yiqijiangzhuohuoxuetongluo-method-to-delay-the-occurrence-of-end-stage-renal-disease-in-diabetic-kidney-disease--study2-100595619",false,"NCT07034807","YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study2","Evidence-based Evaluation of Yiqi Jiangzhuo Huoxue Tongluo Method in Delaying the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study 2","Inclusion Criteria:\n\n* 1 In line with the diagnostic criteria of Western medicine type 2 DKD ;\n* 2 18-80 years old, regardless of gender ;\n* 3 30ml \u002F min \u002F 1.73m2 ≤ eGFR \\\u003C 60ml \u002F min \u002F 1.73m2 ( eGFR was calculated according to CKD-EPI formula ) ;\n* 4 In line with the diagnostic criteria of qi deficiency and collateral stasis syndrome in traditional Chinese medicine ;\n* 5 hbA1c between 7-10 % ;\n* 6 uACR ≥ 300mg \u002F g\n* 7 blood pressure ≤ 150 \u002F 90mmHg ;\n* 8 signed the informed consent ;\n\nExclusion Criteria:\n\n* 1 Patients who are currently receiving other traditional Chinese medicines and Chinese patent medicines with DKD therapeutic effects ;\n* 2 combined with other clear renal diseases, such as polycystic kidney disease, glomerulonephritis, renal tumors ;\n* 3 Patients with acute or chronic infection who needed treatment were judged by the researchers not suitable for inclusion in the study ;\n* 4 Patients who participated in any other research drug study and \u002F or received or had received another research drug or intervention treatment ( within one month before signing the informed consent form ) ;\n* 5 patients who were allergic or contraindicated to the planned use of drugs ;\n* 6 There are serious acute or chronic diseases that the major researchers believe may pose an excessive risk to the subjects, including : patients with cardiovascular, cerebrovascular, lung, blood, digestive tract, liver, kidney, neuropsychiatric or infectious diseases ;\n* 7 Patients with a history of immunodeficiency, including patients with other acquired, congenital immunodeficiency diseases, or patients with a history of organ transplantation or planned organ transplantation ;\n* 8 Women with positive pregnancy screening test or lactating or planning to get pregnant in the next 24 months. Female or male patients who were reluctant to use contraception throughout the study period ;\n* 9 patients with a history of malignant tumors within 5 years ;\n* 10 patients with type 1 diabetes ;\n* 11 patients with maintenance dialysis \\> 2 weeks and \u002F or expected maintenance dialysis \\> 8 weeks before treatment and patients who were judged by any researcher not suitable for inclusion in the trial.","ALL","18 Years","80 Years",{"count":142,"type":143},228,"ESTIMATED","INTERVENTIONAL",[146],"NA","Using the practical randomized controlled trial designed by Zelen, the subjects were randomly divided into the experimental group and the control group. The experimental group was given the traditional Chinese medicine prescription ' Shenzhuo Decoction ' ( composed of Astragalus membranaceus, Salvia miltiorrhiza, Leech, Raw Rhubarb, Epimedium, Motherwort ) + basic treatment ( including nutrition, lifestyle, hypoglycemic, hypotensive, lipid-lowering, control of other risk factors, etc. ), the control group was given basic treatment, a total of 1 year of drug intervention, followed up for 1 year.",[149],"Diabetic Kidney Disease (DKD)","NOT_YET_RECRUITING","2025-06-20",{"date":153,"type":154},"2025-06-24","ACTUAL",{"date":156,"type":143},"2025-08-01",{"date":158,"type":143},"2028-07-31",{"name":118,"class":6},5]