[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594442":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":25,"locations":35,"responsibleParty":70,"collaborators":72,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":10,"eligibilityCriteria":88,"healthyVolunteers":85,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":10,"studyType":95,"phases":10,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"The Florey Institute of Neuroscience and Mental Health","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Young adult stroke survivors (age 18 to 55 inclusive)",null,[12],"Other: Observational Cohort",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Observational Cohort","The deep phenotyping observational study observes young adult stroke recovery trajectories and will also explore potential recovery biomarkers via: advanced MRI imaging; samples including blood, saliva, urine and hair stored for future analysis that may include (but is not limited to) proteomics, genomics and cortisol; and, a PET scan sub study involving \\~20 participants (additional inclusion criteria) exploring the association of reactive astrogliosis with recovery outcomes using the experimental Positron Emission Tomography 18F-SMBT-1 tracer (AU TGA CTN in place).\n\nAssociations with personal and environmental factors including: physical activity and sleep quality via device (Actigraph and Somfit) and self-report; exposures such as home and work environments, diet, socioeconomic status, and dental health; quality of life, resilience, and locus of control.\n\nMonitor healthcare utilisation, changes in medication and medical condition, participant experience and response to the assessments.",[9],[19],"Deep phenotyping",[21],{"name":22,"affiliation":23,"role":24},"Vincent Thijs, MD, PhD","Florey Institute of Neuroscience and Mental Health","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Emily Ramage, BPhysio, PhD","CONTACT","+61 3 90357000","emily.ramage@florey.edu.au",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Marie Ferraro, BSc","+61390357000","marie.ferraro@student.unimelb.edu.au",[36,56],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Austin Health","RECRUITING","Heidelberg","Victoria","3039","Australia","AU",{"type":45,"coordinates":46},"Point",[47,48],145.06667,-37.75,{"lat":48,"lon":47},[51,55],{"name":52,"role":28,"phone":53,"phoneExt":10,"email":54},"Vincent Thijs","9035 7000","emily.ramage@wh.org.au",{"name":10,"role":28,"phone":10,"phoneExt":10,"email":30},{"facility":57,"status":58,"city":39,"state":40,"zip":59,"country":42,"countryCode":43,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre","NOT_YET_RECRUITING","3084",{"type":45,"coordinates":61},[47,48],{"lat":48,"lon":47},[64,67,69],{"name":65,"role":28,"phone":66,"phoneExt":10,"email":30},"Emily Ramage","+61 390357000",{"name":52,"role":28,"phone":66,"phoneExt":10,"email":68},"vincent.thijs@florey.edu.au",{"name":52,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":71,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[73,75,77,79,81],{"name":74,"class":6},"University of Melbourne",{"name":76,"class":6},"University of Newcastle, Australia",{"name":37,"class":78},"OTHER_GOV",{"name":80,"class":6},"La Trobe University",{"name":82,"class":6},"The Alfred","100594442","young-stroke-service-deep-phenotyping-exploring-recovery-in-young-adult-survivors-of-stroke-100594442",false,"NCT07019493","Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke","Inclusion Criteria:\n\n1. Between 18 and 55 years.\n2. Within one month of acute stroke confirmed with standard of care brain imaging or clinical diagnosis or for those for whom recruitment \\\u003C1 month of stroke is not possible they may be recruited to participate within 3-months of stroke\n\nExclusion Criteria:\n\n1. Severe, intercurrent or progressive illness likely to EITHER\n\n   1. Have a prognosis for survival under 24 months; OR\n   2. In the opinion of the investigator will mask the importance to the individual participant data (e.g. severe MS, dementia, etc)\n2. Major psychiatric condition requiring medical intervention","ALL","18 Years","55 Years",{"count":93,"type":94},100,"ESTIMATED","OBSERVATIONAL","The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke. The goal is to test how practical it is to carry out a detailed health assessment process-called \"deep phenotyping\"-with this group.\n\nThis process involves collecting a wide range of information and samples from stroke survivors to better understand each participant's condition. The Investigators will look at how well this approach works in practice, including how easy it is to use, whether it's done consistently, and how acceptable it is to participants.\n\nAt the same time, the Investigators will also explore how different factors-such as biological markers (biomarkers), age, sex, type of stroke, lifestyle, and environment-might be related to stroke recovery. This pilot study will prepare for larger studies in the future.",[98,99,100,101],"Stroke Patients","Stroke","Stroke; Sequelae","Young Adults",[103,104,105,106,107,108,109,110],"recovery","young stroke","ischemic stroke","hemorrhagic stroke","poststroke fatigue","post-stroke cognitive impairment","function","mood","2026-04-16",{"date":113,"type":114},"2026-04-21","ACTUAL",{"date":116,"type":114},"2025-07-19",{"date":118,"type":94},"2027-12",{"name":5,"class":6},2]