[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"interventionName\":\"Exposure Therapy\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100347406","a-trial-comparing-interpersonal-therapy-to-exposure-therapy-for-ptsd-due-to-military-sexual-trauma-mst-in-male-and-female-military-personnel-100347406",false,"NCT03803332","A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel","A Non-Inferiority Randomized Controlled Clinical Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Consequent to Military Sexual Trauma","Inclusion Criteria:\n\n* English-speaking\n* Military Sexual Trauma (MST) survivors, with MST defined as actual or threatened sexual violence, from Vietnam era to current Operation Iraqi Freedom\u002FOperation Enduring Freedom\u002FOperation New Dawn\n* Diagnosed with PTSD consequent to MST, with a minimum CAPS score \\> 40\n* Medically stable at time of study enrollment (for persons with chronic injuries and that any disability present does not prevent attendance of weekly outpatient therapy sessions)\n* Ability to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments\n* Stable on psychotropic medication for the prior 60 days\n\nExclusion Criteria:\n\n* Lifetime or current diagnosis of schizophrenia or other psychotic disorder, bipolar disorder\n* Participation in a clinical trial or concurrent evidence-based treatment for MST-related psychiatric conditions or PTSD during the previous 3 months\n* Current evidence of significant unstable medical illness or organic brain impairment such that the patient could not attend sessions regularly or complete assessments\n* Patients who in the investigator's judgment pose a current homicidal or suicidal risk\n* Current or history of substance dependence in the past 90 days.","ALL","18 Years","85 Years",{"count":20,"type":21},208,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to compare two kinds of therapy for Posttraumatic Stress Disorder (PTSD): exposure therapy (ET) and Interpersonal Psychotherapy (IPT). The results of this study will allow us to see if IPT and ET are equally effective in treating PTSD due to Military Sexual Trauma, with the long-term goal of making PTSD treatment effective for as many people as possible.",[27],"PTSD",[27,29,30,31,32],"Military Sexual Trauma","exposure therapy","interpersonal psychotherapy","treatment","RECRUITING","2026-04-14",{"date":36,"type":37},"2026-04-16","ACTUAL",{"date":39,"type":37},"2020-03-09",{"date":41,"type":21},"2027-09",{"name":43,"class":44},"Weill Medical College of Cornell University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":5},"100575800","reward-processing-and-exposure-therapy-for-social-anxiety-disorder-100575800","NCT06776991","Reward Processing and Exposure Therapy for Social Anxiety Disorder","Reward Processing and Exposure Therapy","METER","Inclusion Criteria:\n\n* Diagnosis of social anxiety disorder from the Structural Clinical Interview for DSM 5.\n* Elevated fear of public speaking, defined as a score of \\>= 66 (+1SD from the mean of population norms on a scale of 17-85) on the Public Speaking Anxiety Scale (PSAS; Bartholomay, E. M., \\& Houlihan, D. D. (2016). Public Speaking Anxiety Scale: Preliminary psychometric data and scale validation. Personality and individual differences, 94, 211-215), which is a self-report scale measuring anxiety of public speaking.\n* Low reward processing, defined as a score of \\\u003C56 (less than the population mean) on the Dimensional Anhedonia Rating Scale (DARS) (Rizvi, S. J., Quilty, L. C., Sproule, B. A., Cyriac, A., Bagby, R. M., \\& Kennedy, S. H. (2015). Dimensional Anhedonia Rating Scale (DARS) \\[Database record\\]. APA PsycTests).\n* Medication-free or stabilized on psychotropic medications for a minimum standard length of time (1 month for benzodiazepines and beta blockers, 3 months for SRIs\u002FSNRIs and heterocyclics).\n* Psychotherapy-free or stabilized on alternative psychotherapies other than cognitive or behavioral therapies that were not focused on their anxiety disorder for at least 6 months prior to study entry.\n* Age 18-60.\n* Fluent in English.\n* To conduct MRI version of fear conditioning task, must have no MRI contraindications.\n\nExclusion Criteria (none of the following):\n\n* Recent suicidal ideation with intent or plan - defined as suicidal ideation with intent or plan in the past year.\n* Lifetime history of suicide attempts.\n* History of bipolar disorder, psychosis, intellectual disability, or organic brain damage.\n* Substance use disorder within the last 6 months.\n* Major respiratory, cardiovascular, pulmonary, neurological, or muscular-skeletal diseases.\n* Pregnant or planning to become pregnant for next 6 months.","60 Years",{"count":56,"type":21},94,[24],"The investigators are conducting a clinical trial of therapy for public speaking anxiety. There are many eligibility criteria, but the main ones are that participants need to be socially anxious and have public speaking anxiety. In this clinical trial, all participants will do exposure therapy. Before doing exposure therapy in the study, though, participants will be randomized to do one of two treatments: i) a positive mood treatment, which is designed to increase how positive people feel, and ii) a relaxation treatment, which is designed to help people feel more relaxed. The investigators are doing this study to see whether doing the positive mood treatment or relaxation treatment first will affect how well exposure therapy works.",[60,61,62,63,64],"Social Anxiety Disorder (Social Phobia)","Public Speaking Anxiety","Anhedonia","ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)","Phobic Disorders",[66,67,68,61,62,69,70,71,72],"Exposure Therapy","Anxiety","Social Anxiety","Reward Processing","Inhibitory Retrieval","Positive Affect Treatment","Relaxation Treatment","2026-04-01",{"date":75,"type":37},"2026-04-02",{"date":77,"type":37},"2024-09-26",{"date":79,"type":21},"2029-04-30",{"name":81,"class":44},"University of California, Los Angeles",""]