[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Óscar Cano Pérez\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100641046","permanent-conduction-system-pacing-versus-atrioventricular-management-for-patients-with-wide-qrs-and-patent-av-conduction-100641046",false,"NCT07585799","Permanent Conduction System Pacing Versus Atrioventricular Management for Patients With Wide QRS and Patent AV Conduction","MORE-CSP","Inclusion Criteria:\n\n* age \\> 18 years\n* Any indication for cardiac pacing with an expected VP burden ≤ 10% after 1- month run-in period\n* Baseline wide QRS (≥150 ms) with normal PR or QRS ≥ 130 ms + PR≥230 ms\n* LVEF≥50%\n* Confirmed CSP criteria\n* Signed and dated informed consent\n\nExclusion Criteria:\n\n* Pregnant woman\n* Permanent or long-lasting atrial fibrillation\n* Previous PM\u002FICD\n* Unstable angina, acute Myocardial Infarction (MI), Coronary Artery Bypass Graft (CABG), Percutaneous Coronary Angioplasty (PCI), surgical valve repair or replacement within 90 days prior enrollment\n* Moderate-severe valvular heart disease (unrepaired)\n* Already included in another clinical study that could confound the results of the present study\n* Infiltrative disease or any other genetically or acquired primary myocardial disease\n* Life expectancy \\\u003C 2 years\n* LVEF \\\u003C50%","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","Intraventricular conduction delay alone or in combination with AV conduction delay is associated with a dyssynchronous activation of the ventricles and may result in LV function impairment.\n\nConduction system pacing can restore physiologic ventricular activation in the presence of intraventricular and atrioventricular conduction delays.\n\nPatients with intraventricular conduction delay alone or in combination with AV conduction delay who have a permanent pacemaker indication due to intermittent bradycardia and have predominantly intact AV conduction may benefit from continuous CSP.",[26],"Bradycardia","RECRUITING","2026-05-13",{"date":30,"type":31},"2026-05-15","ACTUAL",{"date":33,"type":31},"2025-07-29",{"date":35,"type":20},"2029-01-15",{"name":37,"class":38},"Óscar Cano Pérez","OTHER",3,""]