[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Affiliated Hospital of Jiaxing University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":141},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,69,93,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100644435","effect-of-continuous-supraglottic-oxygen-insufflation-via-video-laryngoscope-blade-on-apneic-oxygenation-during-tracheal-intubation-under-general-anesthesia-100644435",false,"NCT07662304","Effect of Continuous Supraglottic Oxygen Insufflation Via Video Laryngoscope Blade on Apneic Oxygenation During Tracheal Intubation Under General Anesthesia","Inclusion Criteria:\n\n* Patients aged between 18 and 75 years, with ASA physical status I to III, and scheduled for surgery with general anaesthesia and orotracheal intubation\n\nExclusion Criteria:\n\n* cardiac disease (ischaemic heart disease, heart failure \\[NYHA ≥2 \\],current arrhythmias, pulmonary hypertension)\n* severe asthma, moderate to severe chronic obstructive pulmonary disease\n* pregnancy\n* baseline oxygen saturation \\\u003C95%\n* not capable of understanding study information and signing a written consent","ALL","18 Years","75 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is a prospective, randomized controlled clinical trial aimed at investigating the efficacy and safety of a novel oxygenating video laryngoscope blade during apneic oxygenation for intubation under general anesthesia. Hypoxemia is prone to occur during anesthesia induction, which can lead to severe complications. Apneic oxygenation is an important method to prolong the safe apnea time, but existing oxygen delivery modalities have limitations in applicability. Although the laryngeal oxygen delivery approach combined with video laryngoscopy has theoretical advantages, clinical evidence is insufficient. Therefore, this study was conducted.",[26],"Apneic Oxygenation",[28],"video laryngoscope","NOT_YET_RECRUITING","2026-06-22",{"date":32,"type":33},"2026-06-23","ACTUAL",{"date":30,"type":20},{"date":36,"type":20},"2029-06-22",{"name":38,"class":39},"Affiliated Hospital of Jiaxing University","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},"100619102","the-90-effective-ventilation-pressure-ep90-for-esophageal-insufflation-avoidance-during-anesthesia-induction-100619102","NCT07340255","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: A Bias-Coin Design With Up-and-Down Sequential Allocation Trial","Inclusion Criteria:\n\n1. Age: 18-65 years, regardless of gender;\n2. ASA classification: I-III;\n3. Scheduled for elective general anesthesia surgery;\n4. BMI: 18.0-28.0 kg\u002Fm²;\n5. Preoperative fasting: Solid food \\>6 hours, liquid \\>2 hours;\n6. Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36);\n7. No severe underlying conditions such as heart, lung, liver, or kidney disease;\n8. Signed informed consent and ability to cooperate with the study protocol.\n\nExclusion Criteria:\n\n1. Pregnant or breastfeeding women;\n2. History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;\n3. Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;\n4. Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;\n5. Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \\\u003C 92% for 30 seconds, unresponsive to treatment);\n6. History of contraindications or allergies to study medications;\n7. Inability to understand the study content or refusal to cooperate;\n8. Oropharyngeal or facial pathology;\n9. with an indwelling gastric tube, and who had previously undergone gastric surgery.","65 Years",{"count":49,"type":20},60,[23],"Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.",[53,54],"Airway Management","Induction of Anesthesia",[56,53,57,58],"Esophageal Insufflation","Ventilation","Bias-coin Design","RECRUITING","2026-01-13",{"date":62,"type":33},"2026-01-14",{"date":64,"type":33},"2025-09-29",{"date":66,"type":20},"2026-02",{"name":38,"class":39},1,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":75,"minAge":16,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":21,"phases":79,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":4},"100613927","effects-of-ultrasound-guided-stellate-ganglion-block-and-transcutaneous-auricular-vagus-nerve-stimulation-on-sleep-quality-after-radical-mastectomy-for-breast-cancer-100613927","NCT07272954","Effects of Ultrasound-Guided Stellate Ganglion Block and Transcutaneous Auricular Vagus Nerve Stimulation on Sleep Quality After Radical Mastectomy for Breast Cancer","Inclusion Criteria:\n\n* aged 18-80 years who underwent radical surgery for breast cancer\n* ASA I-III\n\nExclusion Criteria:\n\n* 1\\. Patients with coagulation dysfunction;\n* Patients with suspected regional infection leading to severe nerve damage in the affected limb;\n* Patients with congenital heart disease, coronary artery disease, myocardial infarction, severe cardiac conduction block, or those with implanted cardiac pacemakers;\n* Patients with severe neurological disorders such as cerebral infarction, cerebral hemorrhage, or stroke;\n* Patients with pain, lesions, infections, or unresolved external ear trauma in the area near the external ear;\n* Patients with severe mental illness or a history of substance abuse related to analgesics or psychiatric medications;\n* Patients with allergies to local anesthetics such as lidocaine or ropivacaine, as well as to general anesthetics;\n* Patients and their families who refuse surgical anesthesia and those unable to complete the survey questionnaire.","FEMALE","80 Years",{"count":78,"type":20},136,[23],"This study aims to design a prospective, randomized, controlled, dual-center, non-inferiority trial to compare the effects of ultrasound-guided sympathetic ganglion block (SGB) and transcutaneous auricular vagus nerve stimulation (taVNS) on sleep quality following radical mastectomy for breast cancer. The objective is to explore whether non-invasive neuromodulation for sleep is non-inferior to invasive neuromodulation. Participants will be randomly assigned to receive either SGB or taVNS treatment. Sleep quality will be assessed using an actigraphy device and sleep scales within four days post-surgery, and the incidence of sleep disturbances will be followed up within 30 days post-surgery.",[82],"Sleep Disorder (Disorder)",[84],"taVNS","2025-12-08",{"date":87,"type":33},"2025-12-09",{"date":89,"type":20},"2026-12-01",{"date":91,"type":20},"2029-12-01",{"name":38,"class":39},{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":21,"phases":102,"briefSummary":103,"conditions":104,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":4},"100612952","effect-of-transcutaneous-auricular-vagus-nerve-stimulation-on-postoperative-opioid-consumption-in-patients-undergoing-major-abdominal-surgery-100612952","NCT07260266","Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Opioid Consumption in Patients Undergoing Major Abdominal Surgery","Inclusion Criteria:\n\n* Age between 18 and 85 years, regardless of gender\n* ASA physical status classification I-III\n* Scheduled for elective major abdominal surgery under general anesthesia, with postoperative admission to the AICU for monitoring\n* Anticipated duration of stay in the AICU is approximately 24 hours\n\nExclusion Criteria:\n\n* History of vagus nerve-related diseases (such as vasovagal syncope);\n* Severe arrhythmias or implanted electronic devices such as pacemakers;\n* Skin lesions, infections, or deformities at the site of external ear stimulation;\n* Long-term preoperative use of opioid medications or sedatives;\n* Allergy to study-related medications;","85 Years",{"count":101,"type":20},108,[23],"This study aims to design a prospective, double-blind, randomized controlled trial to compare the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative visceral pain in patients undergoing major abdominal surgery. Participants will be randomly assigned to receive either taVNS or sham stimulation. The total consumption of opioids and other analgesics within 24 hours post-surgery in the AICU will be recorded, along with follow-up assessments of pain scores and quality of recovery scores (Qor-15) at 24 hours postoperatively.",[105],"Pain Management",{"date":107,"type":33},"2025-12-16",{"date":109,"type":20},"2026-01-01",{"date":111,"type":20},"2027-12-30",{"name":38,"class":39},{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":15,"minAge":120,"maxAge":76,"enrollmentInfo":121,"targetDuration":4,"studyType":21,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":68},"100565386","feasibility-of-deep-inspiratory-internal-jugular-vein-variability-in-guiding-preoperative-fluid-replacement-100565386","NCT06641505","Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement","Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement：A Prospective, Randomized Controlled Study","Inclusion Criteria:\n\n* age over 60 years； American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ； Surgery with radial artery puncture； Propofol induction；\n\nExclusion Criteria:\n\n* BMI≥30kg\u002Fm2； People with short necks； Previous hypotension (systolic blood pressure \\\u003C90mmHg or mean arterial pressure\\\u003C65mmHg)； Previous poorly controlled hypertension； Cardiac insufficiency , EF value\\\u003C50%； Upper limb deep vein thrombosis； History of radiotherapy or neck surgery； Inability to maintain a supine position for necessary measurements； Mechanical ventilation status or inability to take deep breaths patients； gastrointestinal surgery； Patients allergic to propofol； Restricted fluid intake；","60 Years",{"count":122,"type":20},80,[23],"Compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction, so as to evaluate the feasibility of using the internal jugular vein variability under deep inspiration to guide preoperative fluid infusion.",[126],"Hemodynamic",[128,129,130,131,132],"Internal jugular vein","propofol","hemodynamic","hypotension","fluid replacement","2024-11-13",{"date":135,"type":33},"2024-11-15",{"date":137,"type":33},"2024-08-01",{"date":139,"type":20},"2025-06-01",{"name":38,"class":39},""]