[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ahmed Nassar Ibrahim Mohammed\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100619376","early-phase-1-iv-injection-of-metoclopramide-with-or-without-dexamethasone-100619376",false,"NCT07343817","IV Injection of Metoclopramide With or Without Dexamethasone","Ultrasonic Evaluation of Metoclopramide With or Without Dexamethasone on Gastric Motility in Traumatic Patients","Inclusion Criteria\n\n* Traumatic patients undergo emergency operations\n* 18-60 years of age\n* 155-180 cm in height\n* Body mass index \\\u003C30 kg\u002Fm2\n\nExclusion Criteria:\n\n* A history of diseases of important organs, such as diabetes, gastro-paresis, liver and kidney dysfunction, and cardiopulmonary insufficiency.\n* Contraindications for metoclopramide or dexamethasone treatment.\n* Taking opioids or drugs that affect gastric motility.\n* A history of esophageal, gastric, or upper abdominal surgery.\n* A need for immediate emergency surgery, resulting in insufficient study time (120 min).\n* Inability of the patient or their family to understand the study protocol.","ALL","16 Years","50 Years",{"count":5,"type":20},"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","Reflux and the aspiration of gastric contents have always been important focal points. Previous study stated that trauma is an important factor in aspiration pneumonia.\n\nOften, emergency trauma patients have residual gastric contents due to the ingestion of food before injury, the accidental swallowing of nasal and\u002For oral blood after injury, and delayed gastric emptying due to stress, pain, or the use of opioids.\n\nDuring sedation or general anesthesia, such satiated patients are often at risk of aspiration due to a reduction in lower esophageal sphincter tension and the protective inhibition of the airway reflex.\n\nPerioperative gastric ultrasound can be performed at a bedside ultrasound unit; it can safely, non-invasively, conveniently, and effectively evaluate the fullness of a patient's stomach and the nature of their gastric contents.\n\nIt can also be used in the selection of an appropriate method for the anesthetic induction process and can reduce the risk of vomiting, aspiration, and related complications.\n\nAs a gastric motility-promoting drug, metoclopramide can accelerate gastric emptying.\n\nDexamethasone reduced the incidence of nausea and vomiting and improve gastric motility.",[26],"Trauma Injury",[28],"Poly trauma","NOT_YET_RECRUITING","2026-01-14",{"date":32,"type":33},"2026-01-15","ACTUAL",{"date":35,"type":20},"2026-07-01",{"date":37,"type":20},"2028-04-01",{"name":39,"class":40},"Ahmed Nassar Ibrahim Mohammed","OTHER",""]