[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Anglia Ruskin University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":147},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,66,96,121],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100645352","relational-music-therapy-procedural-support-for-paediatric-patients-and-families-facing-repeated-invasive-procedures-100645352",false,"NCT07680348","Relational Music Therapy Procedural Support for Paediatric Patients and Families Facing Repeated Invasive Procedures","Relational Regulation: A Relational Approach to Music Therapy-based Procedural Support for Paediatric Patients and Families Facing Repeated Invasive Procedures","Inclusion Criteria:\n\n* Paediatric patient (ages 5-12) undergoing recurring needle procedures (venipuncture, intravenous (IV) cannulation, subcutaneous injections, intramuscular (IM) injections, Port-a-Cath, lumbar punctures, and bone marrow transplant, aspiration or biopsy)\n* Parents or caregiver of a paediatric patient (ages 5-12) undergoing recurring needle procedures.\n* Willing to participate in music therapy-based sessions.\n* Able to complete brief questionnaires and\u002For take part in an interview.\n* Paediatric inpatient, outpatient, or palliative care unit.\n\nExclusion Criteria:\n\n* Patients currently under heavy sedation or anaesthetic medication that impairs consciousness during data collection.\n* Medically unstable or emergency care patients where participation may interfere with clinical care.\n* Non-English or non-Norwegian speakers where language barriers may pose difficulties in participants understanding study information, and issues in interpretation and analysis of collected data.\n* Patients with severe cognitive or developmental impairment making meaningful engagement with the intervention difficult.\n* Severe behavioural\u002Fpsychiatric conditions that will make safe participation difficult or impossible.","ALL","5 Years","12 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study explores how personalised music therapy can support children and their parents during repeated medical procedures, such as blood tests or injections. Many children find these procedures painful or frightening, and repeated experiences can lead to high anxiety and difficulty coping. Parents often feel distressed as well, which can affect how well they are able to support their child. Because children and parents regulate each other emotionally, helping both members of the pair is important for reducing distress.\n\nThis study aims to explore how personalised music therapy-based procedural support (MTPS) influences the relational and emotional processes that help children and their parents cope, regulate, and build resilience during repeated medical procedures.",[27,28,29,30,31],"Paediatric","Invasive Procedure","Relation, Family","Music Therapy","Procedural Fear","NOT_YET_RECRUITING","2026-06-25",{"date":35,"type":36},"2026-07-02","ACTUAL",{"date":38,"type":21},"2026-09",{"date":40,"type":21},"2027-01",{"name":42,"class":43},"Anglia Ruskin University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":4},"100642327","the-effect-of-physical-activity-on-knee-osteoarthritis-pain-and-gait-100642327","NCT07649863","The Effect of Physical Activity on Knee Osteoarthritis, Pain and Gait","The Effect of Retro Walking on Pain and Gait Biomechanics Using Non-linear Analysis in People With Knee Osteoarthritis","Inclusion Criteria:\n\n* Male and female\n* Any ethnicity\n* Adults over 18 years old\n* Meet the UK guidelines for physical activity supported by NICE (National Institute for Health and Care Excellence) and NHS (able to exercise if it is safe with regular breaks)\n* Otherwise, adults with clinically diagnosed knee osteoarthritis according to NICE criteria or confirmed by a healthcare professional able and willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Any musculoskeletal injury\n* Any conditions known to affects gait (e.g. Parkinson's disease or stroke)\n* Any surgical intervention in the previous 12 months on lower limbs\n* Surgical replacement of hip or knee joints\n* BMI (body mass index) over 35\n* Athletes or take part in significant recreational activity\n* Takes any medication known to affect the gait and ability to walk\n* Received an intra-articular injection in the last 3 months\n* Have been told by medical professionals that they should not take part in any intensity exercise\u002Fphysical activity","18 Years",{"count":53,"type":21},44,[24],"Knee osteoarthritis, a chronic musculoskeletal disease, is the most prevalent type of osteoarthritis and the leading cause of disability and major healthcare costs worldwide. The pathogenesis of the disease is not fully understood and there are few non-invasive disease-modifying therapies available to patients. Therefore, there is a critical need to enhance therapeutic interventions, which requires improvement of our understanding of knee osteoarthritis pathogenesis.\n\nIncreasing evidence suggests that physical activity and exercise training are cost-effective and widely available interventions for the treatment of knee osteoarthritis, however, consideration of type of physical activity and optimal exercise modality are needed to reduce pain, improve gait, knee joint function, stiffness, and muscle weakness in individuals with knee osteoarthritis.\n\nThe aim of this pilot clinical trial is to compare individuals with knee osteoarthritis who have not exercised with individuals that have performed retro walking exercise chosen from the systematic review and survey we have conducted previously to reduce pain and improve gait.\n\nNon-linear analyses will be performed to determine the effects of exercise intervention on gait biomechanics and stability of movement in these patients. These findings may form a basis for recommendations of exercise\u002Fphysical activity interventions for the benefits of patients with knee osteoarthritis including pain reduction, mobility improvement and gait modification.",[57],"Osteoarthritis (OA) of the Knee","2026-06-11",{"date":60,"type":36},"2026-06-16",{"date":62,"type":21},"2026-07",{"date":64,"type":21},"2026-12",{"name":42,"class":43},{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":16,"minAge":74,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},"100609095","the-effect-of-short-term-supplementation-of-oliphenolia-on-fat-oxidation-100609095","NCT07210099","The Effect of Short-term Supplementation of OliPhenolia® on Fat Oxidation","The Effect of Short-term Supplementation of OliPhenolia® on Fat Oxidation in Recreationally Active Volunteers","Inclusion Criteria:\n\n* Men and women, UK based, above 21 years of age with a body mass index (BMI) \\>18 and \\\u003C30 kg·m2 determined during baseline testing\n\n  * Considered to be recreationally active i.e. approximately 150mins of general physical activity\u002F exercise per week (meeting the WHO physical activity guidelines); and a VO2peak (fitness) score \\>20 and \\\u003C50 mL·kg-1·min-1 determined during baseline testing.\n  * No known history (including family history) of heart abnormalities, hypertension, coronary heart disease or diabetes (determined from pre-study health screen questionnaire).\n  * Not currently suffering from any musculoskeletal injury, or any other reason that may prevent participation in cardiovascular exercise.\n  * Have not suffered from recent viral infections ie: influenza (defined within the prior 2 months).\n  * Not taking any prescribed or over-the-counter medication which may influence exercise training (with the exception of inhalers for exercise induced asthma or contraceptive pill).\n  * Not consuming or prepared to refrain from consumption, any commercial supplementation which conflicts with the study parameters ie: antioxidants.\n  * No known allergy or intolerance to olives or prune\u002Fgrape juice, or any known side effects from caffeine ingestion.\n\nExclusion Criteria:\n\n* If any of the above criteria is not met.",true,"21 Years",{"count":76,"type":21},40,[24],"There is current research interest in the use of fruit and plant-based food products containing high levels of natural antioxidants and their impact on exercise, which may be particularly beneficial for recreationally or low-active populations. One such product is an olive extract drink (called OliPhenolia®) produced by Fattoria La Vialla (an organic farm based in Northern Italy) and commercially available for the general public. Whilst previous research from the investigators (at Anglia Ruskin University) using this product has demonstrated potential antioxidant benefits and reduced oxygen cost during aerobic exercise, there are to date no studies investigating whether the short-term consumption of OliPhenolia® can benefit fat oxidation during exercise or whether such effects can be further enhanced employing a pre workout caffeinated beverage.\n\nTherefore the aim of this study is two-fold:\n\ni) to assess the impact of short-term supplementation (8 days) of OliPhenolia® relative to body mass on fat oxidation during aerobic cycling exercise in comparison to placebo in healthy recreationally active volunteers; and ii) whether potential benefits of OliPhenolia® on fat oxidation are enhanced with a pre-workout caffeinated beverage in comparison to placebo in healthy recreationally active volunteers.",[80],"Healthy",[82,83,84,85],"FatMax","Fat Oxidation","Polyphenols","Caffeine","RECRUITING","2026-03-26",{"date":89,"type":36},"2026-03-31",{"date":91,"type":36},"2025-05-30",{"date":93,"type":21},"2026-09-30",{"name":42,"class":43},1,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100605365","virtual-reality-digital-therapeutics-for-seasonal-affective-disorder-100605365","NCT07161570","Virtual Reality Digital Therapeutics for Seasonal Affective Disorder","Effectiveness of Virtual Reality Digital Therapeutics for Seasonal Affective Disorder.","VR-SAD","Inclusion Criteria:\n\n* fluent in English and capable of giving informed consent\n* 18 or older\n* resident in the United Kingdom and\n* able to access internet and attend Anglia Ruskin University's Cambridge campus\n* must self-identify or have been diagnosed with SAD, with moderate to severe symptoms\n\nExclusion Criteria:\n\n* declared suffering from epilepsy (due to the risk that seizures may be triggered by VR use).\n* currently using photosensitizing medications or have significant retinal pathology, due to potentially detrimental effects of light box use. For other ophthalmologic conditions, consultation with an ophthalmologist will be recommended.\n* currently receiving active treatment for SAD, including antidepressant medication (less than 3 months), bright light treatment, or psychotherapy (e.g. CBT for seasonal affective disorder).",{"count":105,"type":21},60,[24],"Seasonal Affective Disorder (SAD) is commonly treated with bright light therapy. Virtual reality (VR) is an immersive computer-generated environment, which has been used to treat mental health difficulties, such as depression, social anxiety and stress. This study aims to compare the use of VR with bright light therapy in treating SAD.\n\nParticipants will be randomly allocated to either the VR condition or the light box condition and instructed to use the respective device every day for 14 days.",[109],"Seasonal Affective Disorder (SAD)",[111,112],"SAD","VR","2025-09-04",{"date":115,"type":36},"2025-09-08",{"date":117,"type":21},"2025-10-27",{"date":119,"type":21},"2026-12-31",{"name":42,"class":43},{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":22,"phases":130,"briefSummary":131,"conditions":132,"keywords":136,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":95},"100533262","neural-mechanisms-of-music-intervention-chronic-arm-hemiparesis-following-stroke-a-single-case-series-eeg-study-100533262","NCT06223529","Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study","The Neural Mechanisms of Music Intervention for Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study","Inclusion Criteria:\n\n1. Aged 18+\n2. Ischemic stroke\n3. Three weeks to 60 months post-stroke\n4. 12 to 49\u002F57 Action Research Arm Test (ARAT) score \\*\n5. Able to follow instructions and consent\n6. Right-hand dominant\n\nExclusion Criteria:\n\n1. Hemorrhagic stroke\n2. No movement in arm\n3. Unable to move thumb and one finger. Loss of sensation and proprioceptive impairment will not lead to exclusion.\n4. Unable to consent to participate\n5. Currently receiving music therapy\n6. Left-hand dominant\n7. Ambidextrous\n8. Not registered with a GP. We will require GP details to inform them in case of any incidental findings in the EEG.","110 Years",{"count":5,"type":21},[24],"The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures.\n\nSecondly, the researchers will measure for changes in arm function before and after the three-week music intervention.\n\nThis is a single-arm pre-\u002Fpost experiment\n\nPrimary research questions:\n\nWhat are the neuroplastic changes induced by Therapeutic Instrumental Music Performance (TIMP)?\n\nSecondary research questions What are the functional changes in hemiparetic arm and hand induced by TIMP?\n\nParticipants will be recruited once they have completed their statutory community stroke rehabilitation.\n\nThey will receive 15 X music therapy sessions in their home over three-weeks. Exercises will be delivered by trained clinicians, including music therapists and stroke rehabilitations specialists.\n\nExercises will be facilitated for full range of arm movement, using a range of percussion instruments on stands and handheld, and iPad with touchscreen instruments, which include keyboards and string instruments that can be played using pinch-grip, holding a stylus\u002Fplectrum.\n\nPre-\u002Fpost intervention period EEG recordings will made. Stroke Specific Quality of Life (SSQoL), Action Research Arm Test and nine-hole-peg-test data will be collected from participants in their homes at weeks: 1, 4, 7 and 10.",[133,134,135],"Stroke","Hemiparesis","Home-based",[137,138],"Neurologic Music Therapy","electroencephalography","2024-07-30",{"date":141,"type":36},"2024-07-31",{"date":143,"type":36},"2024-07-01",{"date":145,"type":21},"2025-05-01",{"name":42,"class":43},""]