[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ankara Yildirim Beyazıt University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":628},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,42,0,25,[9,52,79,102,120,142,162,192,221,253,275,304,328,350,375,403,423,439,460,481,509,531,558,580,603],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100644975","testing-the-reliability-of-kinovea-video-analysis-software-in-measuring-knee-and-hip-angles-during-sit-to-stand-tasks-100644975",false,"NCT07676149","Testing the Reliability of Kinovea Video Analysis Software in Measuring Knee and Hip Angles During Sit-to-Stand Tasks","Reliability of Kinovea for Knee and Hip Angle Measurements During Sit-to-Stand","Inclusion Criteria:\n\n* Be between the ages of 18 and 45\n* Have a body mass index (BMI) between 18 and 25 kg\u002Fm²\n* Be able to sit down and stand up independently\n* Be a volunteer\n\nExclusion Criteria:\n\n* Having previously undergone lower extremity and spinal surgery\n* Having a neurological, orthopedic, or vestibular condition that may affect balance and muscle strength\n* Having sustained a lower extremity and\u002For spinal injury within the last 6 months\n* Having spinal problems such as scoliosis or lumbar disc herniation\n* Having congenital orthopedic problems such as hemimelia, dysmelia, or leg length discrepancy\n* Being pregnant",true,"ALL","18 Years","45 Years",{"count":22,"type":23},35,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to evaluate the intra-observer and inter-observer reliability of the Kinovea video analysis software in measuring knee and hip angles during the sit-to-stand movement. Participants will perform sit-to-stand tasks while being video-recorded. The recorded movements will be analyzed using the Kinovea software to determine the consistency and reliability of joint angle measurements.",[27,28],"Biomechanical Phenomena","Healthy Volunteers",[30,31,32,33,34,35,36,37,38],"Kinovea","Reliability","Sit-to-stand","Video analysis","Joint angles","Inter-rater reliability","Intra-rater reliability","Hip joint","Knee joint","NOT_YET_RECRUITING","2026-06-24",{"date":42,"type":43},"2026-06-30","ACTUAL",{"date":45,"type":23},"2026-06-29",{"date":47,"type":23},"2026-07-20",{"name":49,"class":50},"Ankara Yildirim Beyazıt University","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":12,"sex":59,"minAge":19,"maxAge":20,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":51},"100644208","effects-of-visceral-osteopathic-massage-on-semen-parameters-and-hemodynamics-factors-in-varicocele-100644208","NCT07665905","Effects of Visceral Osteopathic Massage on Semen Parameters and Hemodynamics Factors in Varicocele","Investigation of the Effects of Visceral Osteopathic Massage Techniques on Semen Parameters and Hemodynamic Factors in Men With Varicocele: A Randomized Controlled Study","Inclusion Criteria:\n\n1. Male individuals aged 18-45 years.\n2. Diagnosis of varicocele confirmed by clinical examination and Doppler Ultrasound.\n3. Not being considered a candidate for surgery by a urology specialist.\n4. Following a follow-up protocol based on spermiogram results.\n5. Having at least one varicocele-related abnormality in spermiogram parameters according to WHO 2021 standards.\n6. Providing voluntary consent to participate in the study.\n\nExclusion Criteria:\n\n1. History of prior inguinal or scrotal surgery.\n2. Presence of active urogenital infection or malignancy.\n3. History of spinal or abdominal surgery that would contraindicate complementary medicine interventions.\n4. Having systemic inflammatory, rheumatologic, or endocrinologic diseases.\n5. Receiving additional medical or surgical intervention during the study period beyond routine medical treatment.\n6. Sperm quality changes due to hypogonadotropic causes.\n7. Use of prescribed purified flavonoid fraction venotonics for venous congestion and endothelial dysfunction.\n8. Use of antioxidant supplements (e.g., L-carnitine, L-acetylcarnitine, Ubiquinol, etc.) intended to improve sperm quality.\n9. Refusal to participate in the study.","MALE",{"count":61,"type":23},32,"INTERVENTIONAL",[64],"NA","The project aims to evaluate the effects of a visceral osteopathic manual therapy (VOM) protocol on semen parameters and testicular hemodynamic indicators in men diagnosed with varicocele. Varicocele, the most common correctable cause of male infertility, is a progressive vascular pathology characterized by dilation of the pampiniform plexus veins and venous reflux. Multifactorial mechanisms such as venous valve insufficiency, increased intra-abdominal pressure, microcirculatory impairment, and oxidative stress play a role in the pathophysiology of varicocele. Therefore, the present study investigates the clinical effectiveness of a non-invasive rehabilitation approach aimed at regulating intra-abdominal pressure and improving pelvic venous drainage. The study will be conducted using a prospective, randomized controlled clinical design, including male participants aged 18-45 years diagnosed with varicocele. The intervention group will receive visceral osteopathic manual therapy techniques two times per week for eight weeks, while the control group will receive lifestyle recommendations only. Before and after the intervention, semen analysis results, sperm morphology, motility parameters, and testicular venous hemodynamic measurements obtained by color Doppler ultrasonography will be compared. Parametric and non-parametric statistical methods will be used in the analyses.\n\nThis project aims to generate clinical evidence regarding conservative, complementary medicine-based treatment options in the field of male infertility. Compared to studies on female reproductive health, research focusing on male reproductive health is more limited; therefore, this study is expected to contribute to the literature in this area. The results are anticipated to support the development of a cost-effective and accessible model for infertility treatment processes. In addition, the project aims to provide scientific data for the development of sustainable reproductive health approaches in terms of health economics in Türkiye. The study seeks to determine the effects of visceral osteopathic manual therapy on varicocele-related semen parameters and hemodynamic variables and to contribute to the development of new evidence-based approaches in the management of male infertility.",[67,68],"Varicocele","Infertility",[70,67,68,71],"Osteopathic Physicians","Men's Health","2026-06-18",{"date":40,"type":43},{"date":75,"type":23},"2026-09-01",{"date":77,"type":23},"2027-11-01",{"name":49,"class":50},{"id":80,"slug":81,"hasResults":12,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":51},"100641349","scapular-muscle-activation-and-shoulder-performance-in-migraine-100641349","NCT07656922","Scapular Muscle Activation and Shoulder Performance in Migraine","INVESTIGATION OF SCAPULAR MUSCLE ACTIVATION AND SHOULDER PERFORMANCE IN INDIVIDUALS WITH MIGRAINE","Inclusion Criteria:\n\n* Aged 18-55 years\n* Diagnosed with migraine by a neurologist according to the ICHD-3 criteria\n* Experiencing at least 3 migraine attacks per month\n* Willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Presence of other types of headache disorders\n* History of trauma, fracture, or surgery involving the cranio-cervical region, scapular region, or upper extremity\n* Presence of neurological or inflammatory rheumatic diseases\n* Presence of psychiatric disorders\n* Receiving physiotherapy or rehabilitation for migraine or the cervical, thoracic, or upper extremity regions within the past 6 months\n* Cognitive impairment affecting the understanding of test instructions","55 Years",{"count":88,"type":23},50,"Migraine is a significant health problem due to its high prevalence and substantial contribution to disability. Individuals with migraine have been reported to exhibit myofascial trigger points, increased pain sensitivity, and altered muscle activation patterns, particularly in the trapezius muscles. As the upper and middle trapezius muscles play critical roles in scapular stability and movement, alterations in these muscles may affect scapular orientation and upper extremity function. However, studies investigating the relationship between trapezius muscle activation, scapular orientation, and upper extremity performance in individuals with migraine are limited. Therefore, this study aimed to compare trapezius muscle activation, scapular orientation, and upper extremity performance between individuals with and without migraine. We hypothesized that individuals with migraine would exhibit altered upper and middle trapezius muscle activation, impaired scapular orientation, and reduced upper extremity performance compared with healthy controls.",[91,92,93],"Migraine","Upper Extremity","Muscle Activity","RECRUITING","2026-06-15",{"date":72,"type":43},{"date":98,"type":43},"2026-04-01",{"date":100,"type":23},"2026-07-15",{"name":49,"class":50},{"id":103,"slug":104,"hasResults":12,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":86,"enrollmentInfo":109,"targetDuration":4,"studyType":62,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":51},"100641327","the-effects-of-physiotherapy-in-migraine-100641327","NCT07657377","The Effects of Physiotherapy in Migraine","The Effects of Physiotherapy Applications in Individuals With Migraine","Inclusion Criteria:\n\n* Volunteering to participate in the study\n* Being between 18 and 55 years of age\n* Being diagnosed with migraine by a neurologist according to the International Classification of Headache Disorders 3 (ICHD-3) criteria\n\nExclusion Criteria:\n\n* Diagnosis of other primary and\u002For secondary headaches in addition to migraine,\n* Coexisting neurological and\u002For rheumatological diseases,\n* Severe psychiatric disorders (bipolar disorder, schizophrenia, psychosis, etc.),\n* Pregnancy or lactation,\n* Malignancy,\n* Known arrhythmia or presence of any implanted electronic device,\n* Presence of sensory loss in the application area,\n* Having received physiotherapy or any other treatment in the head\u002Fneck region within the last 12 months,\n* History of head\u002Fneck trauma or surgery within the last 12 months.",{"count":88,"type":23},[64],"The aim of this study is to investigate the effects of a physiotherapy program including cervical muscle training and transcutaneous vagus nerve stimulation on pain, functional status, quality of life, psychological status, and sleep quality in individuals with migraine.",[91],"2026-06-13",{"date":72,"type":43},{"date":116,"type":23},"2026-08",{"date":118,"type":23},"2027-08",{"name":49,"class":50},{"id":121,"slug":122,"hasResults":12,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":12,"sex":127,"minAge":19,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":62,"phases":131,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":51},"100625670","physiotherapy-methods-for-fibromyalgia-100625670","NCT07425652","Physiotherapy Methods for Fibromyalgia","Comparison of the Effects of Different Physiotherapy Methods in Women With Fibromyalgia","Inclusion Criteria:\n\n* Having been diagnosed with fibromyalgia\n* Being female between the ages of 18-65\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Diagnosed neurological and infectious diseases\n* Uncontrolled endocrine and\u002For autoimmune diseases\n* Serious psychiatric disorders (bipolar disorder, schizophrenia, psychosis, etc.)\n* Pregnancy or breastfeeding\n* Malignancy\n* History of known arrhythmia or any implanted electronic device\n* Presence of sensory loss\n* Acute inflammation, open wounds, erythema in massage areas\n* History of any surgery within the last 6 months\n* Having received physical therapy for FM within the last 6 months and\u002For being included in a new treatment program during the study period","FEMALE","65 Years",{"count":130,"type":23},66,[64],"The aim of our study was to examine and compare the effects of different physiotherapy methods, namely connective tissue massage, transcutaneous auricular vagus nerve stimulation and both, on pain, health status, sleep quality, fatigue, psychosocial status, autonomic symptoms and quality of life in women with fibromyalgia.",[134],"Fibromyalgia",{"date":136,"type":43},"2026-06-16",{"date":138,"type":43},"2026-03-01",{"date":140,"type":23},"2028-01",{"name":49,"class":50},{"id":143,"slug":144,"hasResults":12,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":4,"eligibilityCriteria":148,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":128,"enrollmentInfo":149,"targetDuration":151,"studyType":24,"phases":4,"briefSummary":152,"conditions":153,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":161,"locationsCount":51},"100642542","spinal-alignment-spinal-mobility-and-balance-in-patients-with-multiple-sclerosis-100642542","NCT07648277","Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis","Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosis of relapsing-remitting multiple sclerosis (RRMS)\n* Aged between 18 and 65 years\n* EDSS score between 0.5 and 4.5\n* Standardized Mini-Mental State Examination score ≥24\n\nExclusion Criteria:\n\n* Receipt of corticosteroid treatment within the previous 4 weeks\n* Presence of any additional neurological disorder\n* Spasticity defined as a Modified Ashworth Scale score ≥3\n* History of surgical intervention involving the lower extremities, spine, or abdominal region",{"count":150,"type":23},30,"2 Years","Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.\n\nAlthough postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.",[154,155],"Multiple Sclerosis","Balance","2026-06-10",{"date":95,"type":43},{"date":159,"type":43},"2026-02-01",{"date":42,"type":23},{"name":49,"class":50},{"id":163,"slug":164,"hasResults":12,"nctId":165,"briefTitle":166,"officialTitle":166,"acronym":4,"eligibilityCriteria":167,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":62,"phases":170,"briefSummary":171,"conditions":172,"keywords":178,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":191},"100642340","the-effect-of-lateral-wedge-insoles-on-lower-limb-biomechanics-muscle-activity-and-knee-adduction-moment-during-walking-and-running-100642340","NCT07639411","The Effect of Lateral Wedge Insoles on Lower Limb Biomechanics, Muscle Activity and Knee Adduction Moment During Walking and Running","Inclusion Criteria:\n\n* Being able to walk and run 10 meters without assistance\n* Not having sustained any injury to the lower extremities, pelvis, or trunk within the past 12 months\n* Not having received any treatment for the lower extremities, pelvis, or trunk within the past 6 months\n* Shoe size must be between EU 36 (22 cm) and EU 45 (28 cm) according to European Union (EU) standards\n* Must have scored between 0 and +5 on the Foot Posture Index scale for both feet\n* Have scored between 0 and 20 on the Revised Foot Function Index questionnaire\n* Have a body mass index (BMI) between 18 and 25 kg\u002Fm²\n\nExclusion Criteria:\n\n* Having cognitive impairment, vision or hearing problems, or a systemic disease that could affect overall health\n* Having deformities, contractures, or any other abnormalities in the trunk or lower extremities that could affect participation\n\n  • Having a diagnosed foot or ankle deformity (e.g., pes planus, pes cavus, hallux valgus, etc.)\n* Having any neurological or muscular disorder\n* Being an active professional athlete\n* Failure to sign the informed consent form","40 Years",{"count":150,"type":23},[64],"The aim of this prospective, randomized, single-group interventional study is to use quantitative methods to investigate the acute effects of using lateral-wedge insoles on lower extremity biomechanics, muscle activation patterns, and knee adduction moment during walking and running activities in healthy individuals aged 18-40. The primary research questions it seeks to answer are as follows:\n\n* Do lateral wedge insoles cause a significant change in knee adduction moment?\n* Do lateral wedge insoles change lower extremity biomechanics during walking and running?\n* Do lateral wedge insoles change the activation patterns of lower extremity muscles during walking and running? To compare the effectiveness of lateral wedge insoles, participants will randomly use insoles with 0 (neutral), 5, and 10-degree angles.\n\nParticipants will do the following:\n\n* Put on the shoes and insoles provided to you in the motion analysis laboratory and complete the walking and running protocols, each taking 1 minute, on the treadmill.\n* While walking at your normal walking speed, step so that your dominant leg is positioned over the force plate.\n* Repeat all of this for the insoles at the other two angles.",[173,174,175,176,177],"Biomechanical Changes","Gait Biomechanics","Gait Analysis in Healthy Subjects","Running Kinematics","EMG",[179,180,181,182,183],"Lateral Wedges İnsoles","Knee Adduction Moment","Gait Analysis","Running Analysis","EMG Activity","2026-06-06",{"date":156,"type":43},{"date":187,"type":23},"2026-06",{"date":189,"type":23},"2027-06",{"name":49,"class":50},2,{"id":193,"slug":194,"hasResults":12,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":62,"phases":200,"briefSummary":201,"conditions":202,"keywords":206,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":51},"100639779","effect-of-yoga-and-values-clarification-on-stress-comfort-and-emotional-regulation-in-parents-of-children-with-special-needs-100639779","NCT07628569","Effect of Yoga and Values Clarification on Stress, Comfort, and Emotional Regulation in Parents of Children With Special Needs","The Effect of a Comfort Theory-Based Yoga and Values Clarification Intervention on Emotion Regulation, Comfort, and Stress Levels in Parents of Children With Special Needs","Inclusion Criteria:\n\n* Being a parent of a child with special needs,\n* Not having received prior yoga training,\n* Not having a physical problem that would prevent them from practicing yoga,\n* Not having communication problems,\n* Speaking Turkish,\n* Not having learning disabilities,\n* Being suitable\u002Fwilling to work in a group.\n\nExclusion Criteria for Parents:\n\n* Having a physical problem that would prevent them from practicing yoga,\n* The parent not being a volunteer,\n* Not demonstrating compatibility with working in a group.",{"count":130,"type":23},[64],"Parents of children with special needs often experience high levels of stress and difficulties in emotional regulation, which may negatively affect both their well-being and parent-child interactions. This study aims to evaluate the effect of a Comfort Theory-based yoga and values clarification intervention on emotional regulation, comfort, and perceived stress levels in these parents.\n\nThis randomized controlled study will include three groups: a yoga intervention group, a values clarification group, and a control group. Participants will be randomly assigned to groups. Data will be collected using the Emotion Regulation Scale, Perceived Stress Scale, and General Comfort Questionnaire.\n\nThe intervention is expected to improve emotional regulation and comfort levels while reducing perceived stress among parents of children with special needs. The findings may contribute to the development of effective nursing interventions to support caregiver well-being.",[203,204,205],"Stress","Emotional Regulation","Comfort",[207,208,203,209,204,210,211,212],"yoga","Values Clarification","Parents","comfort","Special Needs Children","Nursing Intervention","2026-06-01",{"date":215,"type":43},"2026-06-05",{"date":217,"type":43},"2026-04-29",{"date":219,"type":23},"2026-07",{"name":49,"class":50},{"id":222,"slug":223,"hasResults":12,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":227,"eligibilityCriteria":228,"healthyVolunteers":17,"sex":18,"minAge":229,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":62,"phases":233,"briefSummary":234,"conditions":235,"keywords":240,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":51},"100626902","comfort-intervention-in-picu-children-100626902","NCT07441668","Comfort Intervention in PICU Children","The Effect of a Kolcaba Comfort Theory-Based Child Comfort Intervention on Comfort, Anxiety, Fear, and Sleep in the Pediatric Intensive Care Unit: A Randomized Controlled Trial","CCI-PICU","Inclusion Criteria:\n\n* Child aged 5-10 years\n* Has not received intravenous sedation or anesthetic medication in the past 12 hours\n* Expected to stay in the Pediatric Intensive Care Unit (PICU) for at least 48-72 hours\n* Conscious and able to communicate\n* Glasgow Coma Scale score of 15\n* No pain as assessed by the Wong-Baker FACES Pain Rating Scale\n* Written informed consent obtained from parent\u002Flegal guardian\n* Child and parent able to communicate in Turkish\n* No medical contraindications to non-pharmacological, non-interactive interventions\n\nExclusion Criteria:\n\n* Mechanically ventilated or intubated\n* Hearing impairment\n* Visual impairment\n* Hand motor limitations\n* Severe or profound intellectual disability\n* Epilepsy or history of seizures\n* Severe underweight\n* Chronic respiratory disease\n* Chronic cardiovascular disease\n* Surgical implants\n* Osteoporosis\n* Diagnosis of sleep disorder\n* Use of sleep medication\n* Any physical or mental health condition that prevents communication","5 Years","10 Years",{"count":232,"type":23},86,[64],"This randomized controlled trial evaluates a family-centered comfort intervention for children hospitalized in a pediatric intensive care unit. The intervention consists of listening to the mother's voice, environmental light regulation, and use of a weighted blanket, delivered in addition to routine nursing care. Outcomes include child comfort, anxiety, fear, and sleep parameters, as well as parental anxiety and satisfaction with care. The study will determine whether the intervention improves child and parent outcomes compared with routine care.",[236,205,237,238,239],"Pediatric Intensive Care Unit","Anxiety in Children","Fear","Sleep",[241,242,243,244,238,239],"Pediatric intensive care","Child comfort","Kolcaba Comfort Theory","Anxiety","2026-05-09",{"date":247,"type":43},"2026-05-12",{"date":249,"type":43},"2026-02-20",{"date":251,"type":23},"2027-07-01",{"name":49,"class":50},{"id":254,"slug":255,"hasResults":12,"nctId":256,"briefTitle":257,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":259,"enrollmentInfo":260,"targetDuration":4,"studyType":62,"phases":262,"briefSummary":263,"conditions":264,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":274,"locationsCount":51},"100635383","the-effect-of-an-arcs-model-based-escape-room-simulation-on-nursing-students-knowledge-motivation-and-self-efficacy-regarding-surgical-site-infections-100635383","NCT07551973","The Effect of an ARCS Model-Based Escape Room Simulation on Nursing Students' Knowledge, Motivation, and Self-Efficacy Regarding Surgical Site Infections","Inclusion Criteria:\n\n* Being a nursing undergraduate student\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Being a graduate of any health sciences program\n* Having prior experience with an escape room simulation","30 Years",{"count":261,"type":23},60,[64],"The study is designed as a randomized controlled trial with an experimental and control group, using a pre-test, post-test, and follow-up test design.\n\nAll students who agreed to participate in the study will complete the \"Demographic Information Form,\" the \"Knowledge Test on the Prevention of Surgical Site Infections (pre-test),\" the \"Teaching Material Motivation Scale (pre-test),\" and the \"Nursing Students' Academic Self-Efficacy Scale (pre-test).\" Students will be assigned to the experimental and control groups using simple randomization based on their scores on the Surgical Site Infections Prevention Knowledge Test.\n\nStudents in the experimental group will be briefed on the topic of Surgical Site Infections (CAE) prevention by the researcher. Following the training, an escape room simulation designed according to the ARSC Motivation Model will be conducted. Each escape room simulation will be conducted with 6 students and will consist of a pre-briefing session, the escape room simulation activity, and a debriefing session. During the pre-briefing session, the simulation objectives, the purpose of the scenario, the roles within the scenario, and the game rules will be explained, and the escape room and the standard patient will be briefly introduced to the students in the meeting room. Following this, the students will carry out the scenario and game activities (KAHOOT, Board Game, Card Game, Word Cloud, Crossword Puzzle) in the simulation laboratory, which has been set up as an escape room, accompanied by a standard patient. The researcher will serve as a facilitator during the escape room simulation. If the expected steps are not performed correctly or the game activity is not successfully completed during the session, the team has the right to request a hint from the facilitator. Immediately after the escape room simulation is completed, a debriefing session will be held. The debriefing session, lasting approximately 20-30 minutes per team, will take place in the meeting room located directly across from the escape room. During the debriefing session, students will be encouraged to express their feelings and thoughts, and the researcher will provide feedback.\n\nAll students in the control group will receive instruction on the topic of Surgical Site Infection prevention using the traditional teaching method by the researcher.\n\nAfter the training is completed and 1. month, all students will be administered the \"Surgical Site Infection Prevention Knowledge Test (post-test),\" the \"Teaching Material Motivation Scale (post-test),\" and the \"Nursing Students' Academic Self-Efficacy Scale (post-test).\" Research Questions Does an ARCS-model-based escape room simulation increase nursing students' knowledge levels regarding surgical site infections? Does an ARCS-model-based escape room simulation increase nursing students' learning motivation regarding surgical site infections? Does an ARCS-model-based escape room simulation increase nursing students' self-efficacy regarding surgical site infections?",[265,266,267],"Surgical Site Infections","ARSC Motivation Model","Escape Room Simulation","2026-04-20",{"date":270,"type":43},"2026-04-27",{"date":272,"type":23},"2026-05-01",{"date":42,"type":23},{"name":49,"class":50},{"id":276,"slug":277,"hasResults":12,"nctId":278,"briefTitle":279,"officialTitle":280,"acronym":4,"eligibilityCriteria":281,"healthyVolunteers":17,"sex":18,"minAge":282,"maxAge":283,"enrollmentInfo":284,"targetDuration":4,"studyType":62,"phases":286,"briefSummary":287,"conditions":288,"keywords":292,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":301,"leadSponsor":303,"locationsCount":51},"100633757","occlusal-changes-after-modified-hall-technique-in-molars-affected-by-molar-incisor-hypomineralization-100633757","NCT07530835","Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization","Evaluation of the Occlusal Effects of Stainless Steel Crowns Placed Using the Modified Hall Technique in Permanent Molars Affected by Molar-Incisor Hypomineralization","Inclusion Criteria for Participants\n\n* Absence of any skeletal anomalies\n* ASA physical status I or II according to the American Society of Anesthesiologists classification\n* Frankl behavior rating score of 3 or 4\n* All permanent first molars erupted and in contact at maximum intercuspation\n* Emergency dental needs (e.g., toothache or acute conditions) previously managed\n* Presence of at least one permanent first molar with an MIH-TNI score of 2 or 4 requiring SSC restoration\n* No pain, clicking, or functional limitation in the temporomandibular joint region\n* Children and their legal guardians who read, understand, and provide written and verbal informed consent Inclusion Criteria for Tooth\n* Permanent first molars with MIH Treatment Need Index (MIH-TNI) score of 2 or 4 indicating the need for SSC restoration\n* Occlusal contact with the opposing tooth maintained at maximum intercuspation despite post-eruptive enamel breakdown, with a noticeable reduction in posterior occluso-vertical dimension\n* Absence of clinical and radiographic signs or symptoms associated with irreversible pulp inflammation or necrosis\n* Absence of gingival or periodontal pathology in the surrounding soft tissues\n\nExclusion Criteria\n\n* Individuals with serious systemic or psychological conditions\n* Participants who fail to attend follow-up appointments\n* Those who exhibit excessive fear or anxiety reactions and are unable to cooperate during treatment","6 Years","14 Years",{"count":285,"type":23},46,[64],"Molar-incisor hypomineralization (MIH) frequently affects permanent first molars and increases the risk of rapid post-eruptive breakdown and restorative failure. Stainless steel crowns (SSCs) are considered a reliable treatment option for severely affected molars; however, SSC placement may temporarily alter the occlusal vertical dimension and occlusal contacts. Quantitative evidence describing the occlusal adaptation process following SSC placement in MIH-affected permanent molars is limited.\n\nThis prospective longitudinal clinical study aims to evaluate occlusal adaptation after SSC placement using the modified Hall technique in MIH-affected permanent first molars. Forty-six children will be included. Intraoral scans will be obtained at baseline, immediately after treatment, and during follow-up visits up to 3 months. Digital models will be superimposed to measure three-dimensional changes in cusp position, occluso-vertical dimension, and occlusal contact area. Temporomandibular joint function and periodontal parameters will also be assessed. The results are expected to provide quantitative evidence on occlusal adaptation following SSC treatment in MIH-affected molars.",[289,290,291],"Dental Caries","Dental Occlusion","Pediatric Dentistry",[293,294,295,296],"Hall Technique","Occlusal adjustment","Occlusal vertical dimension","Intraoral scanning","2026-04-14",{"date":299,"type":43},"2026-04-17",{"date":213,"type":23},{"date":302,"type":23},"2027-12-01",{"name":49,"class":50},{"id":305,"slug":306,"hasResults":12,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":4,"eligibilityCriteria":310,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":311,"targetDuration":4,"studyType":62,"phases":313,"briefSummary":314,"conditions":315,"keywords":317,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":321,"lastUpdatePostDateStruct":322,"startDateStruct":324,"completionDateStruct":325,"leadSponsor":327,"locationsCount":51},"100631144","effect-of-upper-extremity-support-on-spatiotemporal-parameters-of-gait-in-individuals-with-stroke-100631144","NCT07496853","Effect of Upper Extremity Support on Spatiotemporal Parameters of Gait in Individuals With Stroke","The Effect of Upper Extremity Support Usage on Spatiotemporal Gait Parameters in Individuals With Stroke: A Prospective Cross-over Experimental Study","Inclusion Criteria:\n\n* Diagnosis of hemiplegia with ICD-10 code G.81.\n* Presence of unilateral hemiplegia.\n* No medical contraindications for the use of assistive devices (e.g., cane, tripod).\n* Aged 18 years or older.\n* Ability to walk for at least 2 consecutive minutes.\n\nExclusion Criteria:\n\n* Presence of aphasia.\n* Recurrent stroke.\n* Montreal Cognitive Assessment (MoCA) score below 10 points.",{"count":312,"type":23},34,[64],"Purpose: The primary goal of this study is to investigate how different levels of upper extremity (arm) support affect walking patterns in individuals who have experienced a stroke. Specifically, the research aims to determine how restricting or facilitating arm swing during walking modulates spatiotemporal gait parameters (such as speed, step length, and rhythm).\n\nBackground: Arm swing plays a crucial role in maintaining balance, stability, and energy efficiency during normal walking. Following a stroke, many patients use walking aids (like canes or walkers) or clinical supports (like parallel bars) that restrict natural arm movement. This study examines whether these restrictions significantly alter gait mechanics in the stroke population.\n\nMethodology: Participants will participate in a cross-over experimental trial. Each participant will walk on a specialized treadmill system (C-Mill VR+) under three randomized conditions: 1. Unsupported walking (no arm support), 2. Single-arm support (using the non-paretic side), 3. Dual-arm support (using both arms).\n\nResearchers will record gait speed, step length, cadence, and duration of stance\u002Fswing phases for each condition.\n\nExpected Outcome: The findings will provide scientific evidence on how different support strategies modulate walking performance. This information will help physical therapists design more effective, individualized rehabilitation programs to improve mobility and quality of life for stroke survivors.",[316],"Stroke",[316,181,318,319,320],"arm swing","upper extremity","spatiotemporal","2026-03-23",{"date":323,"type":43},"2026-03-27",{"date":98,"type":23},{"date":326,"type":23},"2026-12-31",{"name":49,"class":50},{"id":329,"slug":330,"hasResults":12,"nctId":331,"briefTitle":332,"officialTitle":333,"acronym":4,"eligibilityCriteria":334,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":335,"targetDuration":4,"studyType":62,"phases":337,"briefSummary":338,"conditions":339,"keywords":340,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":321,"lastUpdatePostDateStruct":346,"startDateStruct":347,"completionDateStruct":348,"leadSponsor":349,"locationsCount":51},"100626093","effects-of-intensive-virtual-reality-based-balance-and-gait-training-on-activity-performance-and-quality-of-life-in-subacute-stroke-patients-100626093","NCT07431151","Effects of Intensive Virtual Reality-Based Balance and Gait Training on Activity Performance and Quality of Life in Subacute Stroke Patients","The Effects of Intensive Virtual Reality-Based Balance and Gait Training on Activity Performance and Quality of Life in Individuals With Subacute Stroke","Inclusion Criteria\n\n* Diagnosis of hemiplegia (ICD-10 code G81)\n* Age ≥ 18 years\n* Montreal Cognitive Assessment (MoCA) score \\> 10\n\nExclusion Criteria\n\n* Failure to attend three consecutive treatment sessions during the study period\n* Receiving additional balance- or gait-specific rehabilitation interventions (e.g., robot-assisted gait training) during the study period",{"count":336,"type":23},48,[64],"Stroke is one of the leading causes of long-term disability worldwide, and balance and gait impairments are common in the subacute phase, limiting activity performance and quality of life. Early and intensive rehabilitation during the first six months after stroke is considered critical for optimizing functional recovery. Virtual reality-based rehabilitation has emerged as a promising approach to enhance motor learning through task-specific, repetitive, and feedback-driven training.\n\nThis randomized controlled trial aims to investigate the effects of intensive virtual reality-based balance and gait training on activity performance, balance confidence, and quality of life in individuals with subacute stroke. Participants will be randomly allocated to either an intervention group receiving conventional physiotherapy combined with additional virtual reality-based balance and gait training, or a control group receiving conventional physiotherapy alone during the study period. Outcome measures will include functional mobility, balance confidence, cognitive status, and stroke-specific quality of life. The findings of this study may contribute to optimizing rehabilitation intensity and timing strategies in subacute stroke rehabilitation",[316],[341,342,343,344,345],"stroke","virtual reality","rehabilitation","c-mill","augmented reality",{"date":323,"type":43},{"date":159,"type":43},{"date":326,"type":23},{"name":49,"class":50},{"id":351,"slug":352,"hasResults":12,"nctId":353,"briefTitle":354,"officialTitle":355,"acronym":4,"eligibilityCriteria":356,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":357,"targetDuration":4,"studyType":62,"phases":359,"briefSummary":360,"conditions":361,"keywords":363,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":374,"locationsCount":4},"100612001","the-impact-of-patient-education-delivered-through-virtual-reality-100612001","NCT07247903","The Impact of Patient Education Delivered Through Virtual Reality","The Effect of Virtual Reality-Based Education on Preoperative Surgical Fear, Postoperative Pain and Patient Satisfaction in Patients Undergoing Knee Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Be 18 years of age or older,\n* Agree to participate in volunteer work,\n* Have no communication problems in terms of vision, hearing, and perception,\n* Be able to read, speak, and understand Turkish,\n* Have no fear of enclosed spaces.\n\nExclusion Criteria:\n\n* Bilateral Total Knee Arthroplasty.\n* Admission to the clinic on the day of surgery.",{"count":358,"type":23},70,[64],"Objective: A randomized controlled trial was designed to determine the effect of virtual reality-based education provided to patients undergoing knee arthroplasty on preoperative surgical fear, postoperative pain, and patient satisfaction.\n\nMaterials and Methods: The study was designed as a randomized controlled experimental study, with the group receiving animation-based patient education via virtual reality goggles serving as the experimental group and the group receiving routine patient education at the clinic serving as the control group. Research data will be collected using a patient characteristics form prepared by the researcher based on a literature review, a surgical fear scale, a visual analog scale, and a patient education satisfaction scale. Virtual reality glasses will be used as the application tool in the study.",[362],"Knee Arthroplasty",[342,364,365,366,367],"pain","surgical fear","patient satisfaction","knee arthroplasty","2026-01-21",{"date":370,"type":43},"2026-01-22",{"date":372,"type":23},"2026-01-12",{"date":75,"type":23},{"name":49,"class":50},{"id":376,"slug":377,"hasResults":12,"nctId":378,"briefTitle":379,"officialTitle":380,"acronym":381,"eligibilityCriteria":382,"healthyVolunteers":17,"sex":18,"minAge":282,"maxAge":383,"enrollmentInfo":384,"targetDuration":4,"studyType":62,"phases":385,"briefSummary":386,"conditions":387,"keywords":390,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":396,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":402,"locationsCount":51},"100620068","intraosseous-vs-infiltration-anesthesia-in-molar-incisor-hypomineralization-mih-children-100620068","NCT07352813","Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children","A Comparative Evaluation of the Clinical Effectiveness of Computer-Assisted Intraosseous and Infiltration Anesthesia Techniques in Children With Molar-Incisor Hypomineralization","MIH","Inclusion Criteria:\n\n* Individuals applying to the Department of Pedodontics, Ankara Yıldırım Beyazıt University Faculty of Dentistry,\n* Systemically healthy individuals,\n* Individuals without any known allergies,\n* Children between the ages of 6 and 12 years,\n* Scoring 3-4 according to the Frankl Behavior Rating Scale,\n* Children and their legal guardians who, after reading and listening to the informed consent form, fully understand its content and voluntarily provide both verbal and written consent,\n* Children with contralateral and homologous maxillary first permanent molars affected by molar-incisor hypomineralization (MIH) and scoring 3-4 according to the MIH Treatment Need Index criteria,\n* Children with no emergency treatment needs, such as dental pain,\n* Both male and female volunteers.\n\nExclusion Criteria:\n\n\\-","12 Years",{"count":150,"type":23},[64],"This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of permanent first molars affected by Molar-Incisor Hypomineralization (MIH) in children. Clinical effectiveness will be evaluated based on the Visual Analogue Scale (VAS), behavioral pain response, pulse rate , salivary chromogranin A levels, and the need for additional anesthesia.",[388,389],"Molar Incisor Hypomineralization","Hypersensitivity",[391,392,393,394],"caries","dental anxiety","dental pain","molar incisor hypomineralization","2026-01-13",{"date":397,"type":43},"2026-01-20",{"date":399,"type":43},"2025-11-07",{"date":401,"type":23},"2026-12-01",{"name":49,"class":50},{"id":404,"slug":405,"hasResults":12,"nctId":406,"briefTitle":407,"officialTitle":408,"acronym":4,"eligibilityCriteria":409,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":259,"enrollmentInfo":410,"targetDuration":4,"studyType":62,"phases":411,"briefSummary":412,"conditions":413,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":418,"completionDateStruct":420,"leadSponsor":422,"locationsCount":51},"100618814","the-effect-of-escape-room-simulation-on-nursing-students-clinical-decision-making-and-teamwork-attitudes-regarding-cardiopulmonary-resuscitation-100618814","NCT07336511","The Effect of Escape Room Simulation on Nursing Students' Clinical Decision-Making and Teamwork Attitudes Regarding Cardiopulmonary Resuscitation","The Effect of Escape Room Simulation on Nursing Students' Clinical Decision-Making and Teamwork Attitudes Regarding Cardiopulmonary Resuscitation: A Randomized Controlled Study","Inclusion Criteria:\n\n* Being an undergraduate nursing student\n* Voluntarily agreeing to participate in the study\n* Having taken the HSH120 First Aid course in 2025\n\nExclusion Criteria:\n\n* Being a graduate of any health sciences department\n* Students who do not complete the research process for any reason will be excluded from the study.",{"count":261,"type":23},[64],"The study was planned as a randomized controlled trial with a pre-test-post-test-follow-up design involving experimental and control groups.\n\nAll students who agree to participate in the study will be administered the Descriptive Characteristics Form, the Clinical Decision-Making Scale in Nursing (pre-test)\", and the \"Teamwork Attitudes Scale (pre-test)\". Students will be assigned to experimental and control groups using a simple randomization method. Students in the experimental group will receive a lecture on cardiopulmonary resuscitation from the researcher. Following the lecture, an escape room simulation will be conducted. Each escape room simulation will be conducted with 6 students, consisting of a pre-information session, an escape room simulation application, and an analysis session. In the pre-information session, the simulation objectives, the purpose of the scenario, the roles within the scenario, and the game rules will be explained, and the escape room and standard patient will be briefly introduced to the students in the meeting room. Then, students will perform the scenario and game activity (KAHOOT, Table Game, Card Game, Word Cloud, Crossword Puzzle) with a standard patient in the simulation laboratory prepared as an escape room. The researcher will act as a facilitator during the escape room simulation application. During the simulation, if the expected steps are not performed correctly or the game activity is not successfully completed, the team has the right to request hints from the facilitator. Immediately after the escape room simulation is completed, a debriefing session will be held. The debriefing session, lasting approximately 20-30 minutes for each team, will take place in the meeting room located directly opposite the escape room. During the debriefing session, students will be encouraged to express their feelings and thoughts, and feedback will be provided by the researcher. After the debriefing session, and after 1 month the \"Clinical Decision-Making Scale in Nursing (post-test)\" and the \"Teamwork Attitudes Scale (post-test)\" will be administered.\n\nAll students in the control group will be given training on cardiopulmonary resuscitation by the researcher using a traditional training method. After the training is completed, and after 1 month the Clinical Decision-Making Scale in Nursing (post-test) and the \"Teamwork Attitudes Scale (post-test)\" will be administered.\n\nData analysis will be performed using the IBM SPSS Statistics 26 software package.\n\nThe main research questions are:\n\nDoes escape room simulation improve nursing students' clinical decision-making levels regarding cardiopulmonary resuscitation (CPR) practice? Does escape room simulation improve nursing students' teamwork attitudes regarding CPR practice?",[414,415],"Cardiopulmonary Resuscitation (CPR)","ESCAPE ROOM","2026-01-02",{"date":395,"type":43},{"date":419,"type":23},"2025-12-29",{"date":421,"type":23},"2026-02-28",{"name":49,"class":50},{"id":424,"slug":425,"hasResults":12,"nctId":426,"briefTitle":427,"officialTitle":428,"acronym":4,"eligibilityCriteria":429,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":259,"enrollmentInfo":430,"targetDuration":4,"studyType":62,"phases":431,"briefSummary":432,"conditions":433,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":435,"startDateStruct":436,"completionDateStruct":437,"leadSponsor":438,"locationsCount":51},"100618829","the-effect-of-escape-room-simulation-on-nursing-students-knowledge-and-academic-self-efficacy-regarding-stoma-care-100618829","NCT07336706","The Effect of Escape Room Simulation on Nursing Students' Knowledge and Academic Self-Efficacy Regarding Stoma Care","The Effect of Escape Room Simulation on Nursing Students' Knowledge and Academic Self-Efficacy Regarding Stoma Care: A Randomized Controlled Study","Inclusion Criteria:\n\n* Being an undergraduate nursing student\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Being a graduate of any health sciences department\n* Having experience with escape room simulation",{"count":261,"type":23},[64],"This research was planned to determine the effect of escape room simulation on nursing students' knowledge and academic self-efficacy levels regarding stoma care. The research was planned as a randomized controlled trial. This research will be conducted with 60 students of the Nursing Department of Başkent University Faculty of Health Sciences between December 29, 2025 and February 28, 2026. All students who agree to participate in the study will be administered the \"Descriptive Characteristics Form\", the \"Stoma Care and Colostomy Irrigation Knowledge Test (pre-test)\", and the \"Nursing Students Academic Self-Efficacy Scale (pre-test)\". Students will be divided into experimental and control groups using a simple randomization method. Students in the experimental group will be given a lecture on stoma care and irrigation by the researcher. After the training, an escape room simulation will be conducted. Each escape room simulation will be conducted with 6 students, in the form of a pre-information session, an escape room simulation application, and an analysis session. In the pre-information session, the simulation objectives, the purpose of the scenario, the roles within the scenario, and the game rules will be explained, and the escape room and standard patient will be briefly introduced to the students in the meeting room. Then, the students will carry out the scenario and game activity (KAHOOT, Table Game, Card Game, Word Cloud, Crossword Puzzle) with a standard patient in the simulation laboratory prepared as an escape room.\n\nThe researcher will act as a facilitator during the escape room simulation application. During the simulation, if the expected steps are not performed correctly or the game activity is not successfully completed, the team has the right to request hints from the facilitator. Immediately after the escape room simulation is completed, a debriefing session will be held. The debriefing session, lasting approximately 20-30 minutes for each team, will take place in the meeting room located directly opposite the escape room. During the debriefing session, students will be encouraged to express their feelings and thoughts, and feedback will be provided by the researcher. After the debriefing session, and after 1 month the \"Stoma Care and Colostomy Irrigation Knowledge Test (post-test)\" and the \"Nursing Students Academic Self-Efficacy Scale (post-test)\" will be administered.\n\nAll students in the control group will receive instruction on stoma care and irrigation using traditional teaching methods provided by the researcher. After the training is completed, and after 1 month the \"Stoma Care and Colostomy Irrigation Knowledge Test (post-test)\" and the \"Nursing Students Academic Self-Efficacy Scale (post-test)\" will be administered.\n\nData analysis will be performed using the IBM SPSS Statistics 26 software package.\n\nThe main research questions are:\n\nDoes escape room simulation increases nursing students' knowledge levels regarding stoma care? Does escape room simulation increases nursing students' academic self-efficacy regarding stoma care?",[434,415],"Stoma",{"date":395,"type":43},{"date":419,"type":23},{"date":421,"type":23},{"name":49,"class":50},{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":443,"acronym":4,"eligibilityCriteria":444,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":128,"enrollmentInfo":445,"targetDuration":4,"studyType":62,"phases":446,"briefSummary":447,"conditions":448,"keywords":450,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":454,"lastUpdatePostDateStruct":455,"startDateStruct":457,"completionDateStruct":458,"leadSponsor":459,"locationsCount":51},"100598989","effect-of-video-training-on-patients-self-efficacy-after-colorectal-surgery-100598989","NCT07078656","Effect of Video Training on Patients' Self-Efficacy After Colorectal Surgery","IInclusion Criteria:\n\n* aged 18 and over\n* aged 65 and under\n* undergoing laparoscopic general surgery under general anesthesia\n* with no vision, hearing, or perception problems\n* with no communication problems\n* without nausea, vomiting, dizziness, etc.\n* with an ASA score of I, II, or III\n* who voluntarily agreed to participate in the study\n\nExclusion Criteria:\n\n* who have not undergone laparoscopic surgery\n* who are hemodynamically unstable\n* with an ASA score of IV\n* with neurological or psychological problems\n* Emergency and unplanned cases",{"count":130,"type":23},[64],"The purpose of the study is to determine the effect of virtual reality video training on the self-efficacy of patients after colorectal surgery. Thus, correct planning can be provided for trainings that will provide information to patients according to their needs during the nursing care process.\n\nDoes virtual reality video training have an effect on participants' perceptions of self-efficacy after colorectal surgery? The researchers will conduct the self-efficacy survey on another group of participants without repeating the training to see the impact of the training.\n\nParticipants in the experimental group will receive training on the second postoperative day and they will apply a self-efficacy survey on the tenth day after discharge.\n\nParticipants in the control group will not receive training on the second postoperative day. They will complete a self-efficacy survey on the tenth day after discharge.",[449],"Colorectal Cancer",[451,452,453],"Virtual reality video training","colorectal surgery","self-efficacy","2025-12-21",{"date":456,"type":43},"2025-12-23",{"date":187,"type":23},{"date":116,"type":23},{"name":49,"class":50},{"id":461,"slug":462,"hasResults":12,"nctId":463,"briefTitle":464,"officialTitle":464,"acronym":4,"eligibilityCriteria":465,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":128,"enrollmentInfo":466,"targetDuration":4,"studyType":62,"phases":467,"briefSummary":468,"conditions":469,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":473,"lastUpdatePostDateStruct":474,"startDateStruct":476,"completionDateStruct":478,"leadSponsor":480,"locationsCount":51},"100598137","effect-of-breathing-exercise-on-pain-and-quality-of-recovery-in-after-transplantation-patients-a-randomized-controlled-trial-100598137","NCT07067580","Effect of Breathing Exercise on Pain and Quality of Recovery in After Transplantation Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18 and over, 65 and under,\n* Those who have had a transplant for the first time,\n* Patients who volunteer to participate in the study will be included in the study.\n\nExclusion Criteria:\n\n* Hemodynamically unstable,\n* Those who may experience physical strain during breathing exercises and have a disease that may cause increased intra-abdominal pressure (e.g. bleeding hemorrhoids, hernias of all kinds, persistent cough, severe back pain, heart diseases, high blood pressure, urinary incontinence, epilepsy),\n* Those with early complications\n* Those with neurological or psychological problems,\n* Those who were transferred to the intensive care unit after surgery,\n* Emergency and unplanned cases will be excluded from the scope of the research.",{"count":261,"type":23},[64],"The researchers will fill out the \"Patient Introduction Form\" for the patients who agreed to participate in the study after obtaining permission from the experimental group with the \"Informed Consent Form\" the day before the surgery. The breathing exercises will be taught and monitored by the researchers, and the researcher who will implement them is a nurse in the general surgery department. The experimental group will be trained on breathing exercises by the researcher the day before the surgery. The patients will be provided with 1 set (4 breaths) per hour of breathing exercises after the surgery. The patient's vital signs will be monitored before and after the breathing exercise. Patients will not have difficulty during the breathing exercise, and they will be provided with gradual interventions. Pain status will be monitored at 0, 2, 6, 12 and 24 hours during the 24-hour hospital stay. The recovery quality scale will be applied on the 1st and 3rd day after surgery. In the control group, after obtaining permission with the \"Informed Consent Form\" the day before the surgery, the patients who agreed to participate in the study will fill out the \"Patient Introduction Form\" by the researchers, and their pain status will be monitored at 0, 2, 6, 12 and 24 hours during the 24-hour hospital stay after the surgery. The recovery quality scale will be applied on the 1st and 3rd day after surgery. No intervention will be made to the patients in the control group, and they will be provided with routine nursing care provided in the hospital.",[470,471,472],"Transplantation","Pain Management","Quality of Recovery 40","2025-12-12",{"date":475,"type":43},"2025-12-15",{"date":477,"type":43},"2025-08-01",{"date":479,"type":23},"2026-04-30",{"name":49,"class":50},{"id":482,"slug":483,"hasResults":12,"nctId":484,"briefTitle":485,"officialTitle":486,"acronym":4,"eligibilityCriteria":487,"healthyVolunteers":12,"sex":127,"minAge":20,"maxAge":488,"enrollmentInfo":489,"targetDuration":4,"studyType":62,"phases":491,"briefSummary":492,"conditions":493,"keywords":496,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":503,"lastUpdatePostDateStruct":504,"startDateStruct":505,"completionDateStruct":507,"leadSponsor":508,"locationsCount":51},"100615999","imb-based-sleep-hygiene-education-for-menopausal-women-effects-on-sleep-quality-and-depression-100615999","NCT07299903","IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression","The Effect of Information, Motivation, Behavioral Skills (IMB) Model-Based Sleep Hygiene Education on Sleep Quality and Depression Level in Menopausal Women: A Methodological and Experimental Study","Inclusion Criteria:\n\n* Being in menopause\n* Being between 40 and 60 years of age\n* Having a low sleep quality score according to the Menopause-Specific Sleep Quality Scale.\n* Being willing to participate in the study.\n* Having no physical or mental disabilities that would hinder communication.\n* Having technology (smartphone, tablet, or computer) with internet access and the ability to participate in online training.\n\nExclusion Criteria:\n\n* Having a history of receiving psychological support.\n* Having been diagnosed with a chronic psychiatric illness (previously diagnosed depression, anxiety disorder, etc.).\n* Having a neurological or chronic systemic illness that may affect sleep quality.\n* Being treated for a sleep disorder (receiving medication or psychotherapy).\n* Receiving hormone replacement therapy (HT).\n* Having received sleep hygiene training\u002Ftherapy within the last 6 months.","60 Years",{"count":490,"type":23},500,[64],"This study aims to evaluate the effects of sleep hygiene education on sleep quality and depression in women during menopause. Women will be randomly assigned to either an education group or a control group. The education group will receive training based on the Information-Motivation-Behavioral Skills (IMB) Model. Sleep quality and depression levels will be measured before and after the education. The results will provide insight into whether sleep hygiene education can improve sleep quality and reduce depression in menopausal women.",[494,495],"Insomnia","Depressive Symptoms",[497,498,499,500,501,502],"Menopause","Sleep quality","Sleep hygiene","Depression","Women's health","Randomized controlled trial","2025-12-10",{"date":456,"type":43},{"date":506,"type":23},"2026-01-01",{"date":42,"type":23},{"name":49,"class":50},{"id":510,"slug":511,"hasResults":12,"nctId":512,"briefTitle":513,"officialTitle":514,"acronym":4,"eligibilityCriteria":515,"healthyVolunteers":17,"sex":18,"minAge":516,"maxAge":230,"enrollmentInfo":517,"targetDuration":4,"studyType":62,"phases":518,"briefSummary":519,"conditions":520,"keywords":521,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":523,"lastUpdatePostDateStruct":524,"startDateStruct":526,"completionDateStruct":528,"leadSponsor":530,"locationsCount":51},"100603253","occlusal-impact-of-hall-crowns-in-primary-molars-100603253","NCT07134114","Occlusal Impact of Hall Crowns in Primary Molars","Comparative Evaluation of Occlusal Changes Following Hall Technique Crowns in Different Primary Molar Groups: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\nInclusion Criteria for Participants\n\n* No skeletal or dental anomalies,\n* ASA (American Society of Anesthesiologists) physical status classification of I or II ,\n* Frankl Behavior Rating Scale score of 3 or 4,\n* In the mixed dentition stage,\n* Fully erupted permanent first molars in occlusal contact at maximum intercuspation\n* No acute dental pain or need for emergency treatment,\n* Presence of at least two primary molars with carious lesions scored as 3, 4, or 5 according to the ICDAS (International Caries Detection and Assessment System),\n* Presence of an antagonist tooth for the molar planned to receive Hall Technique,\n* Provision of verbal and written informed consent by the participant and legal guardian after reading or listening to the consent form and fully understanding its content.\n\nInclusion Criteria for Tooth\n\nBased on Clinical Examination:\n\n* No history of prolonged pain in response to thermal or chemical stimuli, or spontaneous pain suggestive of irreversible pulpitis,\n* No sensitivity to percussion or palpation,\n* Absence of both pathological and physiological mobility,\n* No signs of swelling, fistula, or discoloration,\n* Sufficient remaining tooth structure to retain a preformed stainless steel crown.\n\nBased on Radiographic Examination:\n\n* Radiolucent lesion associated with dental caries located within the outer one-third to two-thirds of the dentin, with a visible band of normal dentin between the lesion and the pulp,\n* At least two-thirds of root length present,\n* No signs of internal or external pathological or physiological root resorption,\n* Intact lamina dura and normal periodontal ligament space,\n* No periradicular bone loss surrounding the roots,\n* No calcified masses in the pulp chamber.\n\nExclusion Criteria:\n\n* Individuals with serious systemic or psychological conditions\n* Participants who fail to attend follow-up appointments\n* Those who exhibit excessive fear or anxiety reactions and are unable to cooperate during treatment","7 Years",{"count":261,"type":23},[64],"Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance. This study aims to evaluate and compare the occlusal changes that occur following Hall crown placement on different primary molar groups (maxillary first molar, maxillary second molar, mandibular first molar, mandibular second molar) using digital model analysis.",[289,290,291],[522,294,296],"Hall technique","2025-11-19",{"date":525,"type":43},"2025-11-20",{"date":527,"type":43},"2025-09-15",{"date":529,"type":23},"2026-12-15",{"name":49,"class":50},{"id":532,"slug":533,"hasResults":12,"nctId":534,"briefTitle":535,"officialTitle":536,"acronym":4,"eligibilityCriteria":537,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":538,"targetDuration":4,"studyType":62,"phases":540,"briefSummary":541,"conditions":542,"keywords":546,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":550,"lastUpdatePostDateStruct":551,"startDateStruct":553,"completionDateStruct":555,"leadSponsor":557,"locationsCount":51},"100610771","emotional-awareness-and-communication-training-effectiveness-in-oncology-nurses-100610771","NCT07231913","Emotional Awareness and Communication Training Effectiveness in Oncology Nurses","Evaluation of the Effectiveness of Emotional Awareness and Communication-Based Intervention Training for Oncology Nurses","Inclusion Criteria:\n\n* Employed as a nurse in an oncology unit for at least 6 months\n* Voluntarily agrees to participate in the study\n* Able to attend all training sessions\n* Completes both pre-test and post-test questionnaires\n\nExclusion Criteria:\n\n* Currently on leave or planning to take leave during the study period\n* Has received prior structured training related to emotional awareness or communication skills within the past year\n* Diagnosed with a severe psychological disorder that may affect participation",{"count":539,"type":23},64,[64],"This interventional clinical study aims to evaluate whether a structured emotional awareness and communication training program can reduce occupational burnout among oncology nurses. The study will address the following primary questions: Does the intervention lead to a significant increase in nurses' emotional awareness? Does it improve their communication skills in challenging patient and family interactions? Does it reduce their levels of professional burnout? Participants will be recruited from oncology nurses working at Ankara Etlik City Hospital who have been employed in the unit for at least six months and consent to participate. A total of 64 nurses will be randomly assigned to an intervention group (n=32), receiving four weekly face-to-face training sessions over four weeks, or a control group (n=32), receiving educational materials in written\u002Fdigital format. Data will be collected using pre- and post-intervention assessments with the Maslach Burnout Inventory, the Emotional Requirements Scale, and the Communication Skills Scale for Healthcare Professionals. All data will be anonymized and analyzed to determine the effectiveness of the intervention in enhancing emotional awareness and communication skills and in reducing burnout among oncology nurses.",[543,544,545],"Occupational Burnout","Emotional Awareness","Communication Skills",[547,544,548,549],"Oncology Nurses","Professional Well-being","Psychosocial Training","2025-11-14",{"date":552,"type":43},"2025-11-17",{"date":554,"type":43},"2025-10-25",{"date":556,"type":23},"2026-05",{"name":49,"class":50},{"id":559,"slug":560,"hasResults":12,"nctId":561,"briefTitle":562,"officialTitle":563,"acronym":4,"eligibilityCriteria":564,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":565,"targetDuration":4,"studyType":62,"phases":566,"briefSummary":567,"conditions":568,"keywords":569,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":573,"lastUpdatePostDateStruct":574,"startDateStruct":576,"completionDateStruct":577,"leadSponsor":579,"locationsCount":51},"100601638","the-effects-of-augmented-reality-versus-virtual-reality-100601638","NCT07113093","The Effects of Augmented Reality Versus Virtual Reality","Effects of Augmented Reality and Virtual Reality-Assisted Gait Training on Balance and Walking in Individuals With Stroke","Inclusion Criteria:\n\n* ICD-10 diagnosis code of G.81 (Hemiplegia)\n* Age 18 years or older\n* Ability to walk with assistance or independently (Functional Ambulation Classification score of 2 or higher)\n\nExclusion Criteria:\n\n* Incomplete completion of the assessment form\n* Refusal to participate in the study\n* Aphasia\n* Montreal Cognitive Assessment score below 10\n* Presence of extra neurological or orthopedic problems unrelated to stroke\n* Recurrent stroke\n* MAS score of 3-4 (lower extremity)\n* Volunteer's desire to withdraw from the study\n* Inability to adapt to the technological devices used in the study (e.g., visual or hearing impairments)\n* Missing three consecutive treatment sessions\n* Botulinum toxin-A (BONT-A) injection to the lower extremity during the treatment process or within the last 6 months",{"count":130,"type":23},[64],"This randomized controlled trial aims to compare the effects of augmented reality (AR) and virtual reality (VR)-assisted treadmill gait training on balance and walking in individuals with stroke, within the framework of the International Classification of Functioning, Disability and Health (ICF). A total of 66 post-stroke patients will be randomly assigned to three groups: (1) VR group receiving gait training via C-Mill VR applications in addition to conventional physiotherapy, (2) AR group receiving gait training via C-Mill AR applications in addition to conventional physiotherapy, and (3) control group receiving a home exercise program alongside conventional physiotherapy. Participants will train for 45 minutes per day, five days a week, for three weeks. Outcome measures will include clinical, functional, cognitive, and spatiotemporal gait parameters to evaluate changes in balance and walking ability before and after the intervention.",[316],[316,570,571,572],"Virtual Reality","Augmented Reality","Treadmill","2025-10-01",{"date":575,"type":43},"2025-10-03",{"date":477,"type":43},{"date":578,"type":23},"2027-05-31",{"name":49,"class":50},{"id":581,"slug":582,"hasResults":12,"nctId":583,"briefTitle":584,"officialTitle":584,"acronym":4,"eligibilityCriteria":585,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":586,"targetDuration":4,"studyType":62,"phases":587,"briefSummary":588,"conditions":589,"keywords":592,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":597,"lastUpdatePostDateStruct":598,"startDateStruct":600,"completionDateStruct":601,"leadSponsor":602,"locationsCount":51},"100606571","the-effect-of-a-navigator-nurse--supported-mobile-application-developed-based-on-the-imb-model-on-the-quality-of-life-of-patients-with-celiac-disease-100606571","NCT07177287","The Effect of a Navigator Nurse- Supported Mobile Application Developed Based on the IMB Model on the Quality of Life of Patients With Celiac Disease","Inclusion Criteria:\n\n* Age ≥18 years\n* Newly diagnosed with celiac disease\n* Owning a smartphone and able to use the application\n* Able to speak and understand Turkish\n* Voluntary participation (informed consent)\n\nExclusion Criteria:\n\n* Severe gluten hypersensitivity\n* Failure to meet inclusion criteria\n* Withdrawal of consent during the study",{"count":261,"type":23},[64],"This randomized controlled trial aims to evaluate the effect of a navigator nurse-supported mobile application, developed based on the Information-Motivation-Behavioral Skills (IMB) model, on the quality of life of adult patients newly diagnosed with celiac disease. Participants will be randomized into intervention and control groups. The intervention group will use the mobile application with navigator nurse support for six months, while the control group will receive routine clinical education. Outcomes will be assessed through validated questionnaires and clinical data.",[590,591],"Celiac Disease","Adults With Celiac Disease",[593,594,595,596],"quality of life","navigator nurse","mobile application","IMB model","2025-09-27",{"date":599,"type":43},"2025-09-30",{"date":477,"type":43},{"date":213,"type":23},{"name":49,"class":50},{"id":604,"slug":605,"hasResults":12,"nctId":606,"briefTitle":607,"officialTitle":608,"acronym":4,"eligibilityCriteria":609,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":610,"targetDuration":4,"studyType":62,"phases":612,"briefSummary":613,"conditions":614,"keywords":616,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":620,"lastUpdatePostDateStruct":621,"startDateStruct":623,"completionDateStruct":625,"leadSponsor":627,"locationsCount":51},"100607876","the-effect-of-guided-imagery-technique-on-anxiety-pain-and-analgesic-use-in-total-joint-arthroplasty-patients-100607876","NCT07194252","The Effect of Guided Imagery Technique on Anxiety, Pain, and Analgesic Use in Total Joint Arthroplasty Patients","The Effect of Guided Imagery Applied Before and After Surgery on Surgical Anxiety, Pain, and Analgesic Consumption in Patients Undergoing Total Joint Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients who have undergone unilateral arthroplasty surgery,\n* Without cognitive impairment,\n* Who speak and write Turkish,\n* Without hearing or vision problems,\n* Without any other acute illness causing pain or anxiety,\n* Who received the same analgesic agent in the treatment protocol during the postoperative period,\n* And who volunteered to participate in the study will be included.\n\nExclusion Criteria:\n\n* Having a diagnosis of chronic pain syndrome or neuropathic pain,\n* Having a diagnosis of psychiatric illness\u002Fbeing under treatment\n* Continuous use of analgesic\u002Fsedative medication that may affect the pain threshold,\n* Hearing impairment or severe cognitive impairment that prevents participation in guided imagery applications.",{"count":611,"type":23},128,[64],"This randomized controlled study will investigate the effects of guided imagery on preoperative anxiety and postoperative pain and analgesic consumption in patients undergoing total joint arthroplasty. Conducted between September 2025 and June 2026 at a public hospital in Zonguldak, Turkey, the study will include patients scheduled for total joint arthroplasty following ethics committee approval. The intervention group will receive guided imagery twice preoperatively and once daily at 48 and 72 hours postoperatively. Outcomes will be assessed using the Surgical Anxiety Scale, surgery-specific anxiety scale, Numerical Rating Scale (NRS), and analgesic consumption tracking.",[615],"Total Joint Arthroplasty",[364,617,618,619],"anxiety","analgesic","total joint arthroplasty","2025-09-18",{"date":622,"type":43},"2025-09-26",{"date":624,"type":23},"2025-09-22",{"date":626,"type":23},"2026-06-22",{"name":49,"class":50},""]