[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Anqing Municipal Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":153},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,74,102,127],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100592243","comparison-of-the-analgesic-effect-of-oliceridine-versus-morphine-or-sufentanil-for-postoperative-analgesia-in-lumbar-surgeries-a-randomized-control-trial-100592243",false,"NCT06990893","Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial","Inclusion Criteria:\n\n* Lumbar spine surgery with ASA grades I-III\n* Aged 18-65 years\n* Ethically, the patient voluntarily accepted this trial and signed the informed consent form\n\nExclusion Criteria:\n\n* Severe respiratory and circulatory system diseases\n* Nervous system disease\n* Mental and psychological disorders\n* Abnormal liver and kidney functions\n* Participated in another drug clinical research within the past 30 days","ALL","18 Years","65 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","Objective: This study aimed to compare the efficacy and safety of oliceridine versus morphine and sufentanil for postoperative analgesia following elective lumbar spine surgery.\n\nMethods: In this randomized, controlled trial, 90 patients scheduled for lumbar spine surgery were allocated in a 1:1:1 ratio to receive postoperative intravenous patient-controlled analgesia (PCIA) with either oliceridine (Group O，1.5mg oliceridine for loading dose， 0.5mg\u002Fkg oliceridine for PICA), morphine (Group M，4mg morphine for loading dose，1.5mg\u002Fkg morphine for PICA), or sufentanil (Group S，4ug sufentanil for loading dose，1.5ug\u002Fkg sufentanil for PICA). The primary outcome was the movement Visual Analogue Scale (VAS) score at 6 hours postoperatively. Secondary outcomes included resting and movement VAS scores, ramsay sation score at 0.5, 2, 6, 12, 24, and 48 hours postoperatively (excluding the motor VAS score at 6 hours postoperatively); number of PCIA demands and rescue analgesic requirements within 48 hours; hemodynamic parameters at 5, 10, 15, 30, and 60 minutes after administration of the initial loading dose. The incidence of adverse events within 48 hours postoperatively, such as nausea and vomiting, somnolence, respiratory depression, or pruritus.",[26,27,28,29,30],"Sufentanil","Morphine","Validity","Safety","Oliceridine",[26,29,27,32],"oliceridine","RECRUITING","2026-05-28",{"date":36,"type":37},"2026-06-01","ACTUAL",{"date":39,"type":37},"2025-06-01",{"date":41,"type":20},"2026-10-01",{"name":43,"class":44},"Anqing Municipal Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":16,"maxAge":17,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":73,"locationsCount":45},"100590475","different-models-of-tracheal-catheters-are-used-for-female-thyroid-glands-100590475","NCT06967896","Different Models of Tracheal Catheters Are Used for Female Thyroid Glands","A Randomized Controlled Trial Comparing Different Models of Tracheal Tube for Thyroid Surgery in Women","Inclusion Criteria:\n\n* Female;\n* Thyroid surgery should be performed under general anesthesia (GA) at an appropriate time;\n* ASA grade I-III;\n* Aged 18-65 years;\n* BMI less than 35Kg\u002Fm2\n* In line with ethics, patients voluntarily accept this experiment and sign informed consent.\n\nExclusion Criteria:\n\n* Reflux esophagitis, preoperative sore throat, chronic pharyngitis, preoperative hoarseness, use of anticoagulants or corticosteroids, high risk of reflux or aspiration, dysphagia, previous oral or pharyngeal surgical intervention, bleeding disorder, severe heart, lung, liver and kidney dysfunction\n* Upper respiratory tract infection occurred within 2 weeks before surgery\n* Unable to insert ET (no more than two intubations)\n* Patients with hoarseness or sore throat before surgery\n* Language communication, hearing impairment or brain dysfunction such as stroke, unable to communicate","FEMALE",{"count":55,"type":20},180,"OBSERVATIONAL","Objective:Compare whether the use of tracheal catheters of models 6.0 and 6.5 causes less sore throat in women after thyroid surgery compared with the traditional use of model 7.0 tracheal catheters.Methods: Investigators enrolled 180 female patients with American Society of Anesthesiologists (ASA) physical status I and III, aged 18-65 years, and scheduled for elective undergoing thyroid surgery with general anesthesia. The participants were randomly assigned into three groups(n=60 each group):Group A: Tracheal catheter group with an inner diameter of 6.0mm, Group B: Tracheal catheter group with an inner diameter of 6.5mm, Group C: Tracheal catheter group with an inner diameter of 7.0mm.The incidence and severity of postoperative sore throat were recorded in three groups at 1 h, 6 h, 24 h and 48 h after operation.",[59,60,61,62],"Sore Throat","Tracheal Tubes With an Inner Diameter of 6.0mm","Tracheal Tubes With an Inner Diameter of 6.5mm","Tracheal Tubes With an Inner Diameter of 7.0mm",[64,65,66],"thyroid surgery","sore throat","Tracheal tube","2026-05-24",{"date":69,"type":37},"2026-05-27",{"date":71,"type":37},"2025-05-25",{"date":41,"type":20},{"name":43,"class":44},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":15,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100597754","etomidate-and-esketamine-on-postoperative-pain-after-tonsillectomy-undergoing-children-100597754","NCT07062601","Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children","Effect of Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children With General Anesthesia","Inclusion Criteria:\n\n* Children who underwent elective tonsillectomy\n* Aged 2-10 years old\n* ASA class I-II\n\nExclusion Criteria:\n\n* Children with hepatic or renal dysfunction\n* Those with increased intracranial or intra-ocular pressure\n* Children with schizophrenia, bipolar disorder, and any other psychiatric condition\n* Children with preexisting chronic pain\n* Children with preoperative combined sinus bradycardia or atrioventricular block","2 Years","10 Years",{"count":84,"type":20},64,[23],"Objective: To explore the effect of etomidate and esketamine on postoperative pain after tonsillectomy in children.\n\nMethods: Investigators enrolled 64 children with American Society of Anesthesiologists (ASA) physical status I and II, aged 2-10 years, and scheduled for elective undergoing tonsillectomy with general anesthesia. All the enrolled patients were randomly divided into etomidate and fentanyl group (Group A) and etomidate and esketamine group (Group B). In the etomidate-fentanyl group (group A), 0.3 mg\u002Fkg etomidate and 4 µg\u002Fkg fentanyl were given at the induction of anesthesia, followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the surgery, respectively; in the etomidate-esketamine group (group B), induction of anesthesia with 0.3 mg\u002Fkg etomidate and 0.5 mg\u002Fkg esketamine , followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the operation. Anesthesiologists who were unaware of the grouping recorded the FlACC Pain Scale at 2 h, 8 h, and 24 h after surgery.",[88,89,90,91],"Etomidate","Esketamine","Tonsillectomy","Children",[88,93,90],"Esketomine","NOT_YET_RECRUITING","2025-07-10",{"date":97,"type":37},"2025-07-14",{"date":95,"type":20},{"date":100,"type":20},"2025-11-15",{"name":43,"class":44},{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100589276","intravenous-lidocaine-plus-intratracheal-dexmedetomidine-on-postoperative-sore-throat-100589276","NCT06952309","Intravenous Lidocaine Plus Intratracheal Dexmedetomidine on Postoperative Sore Throat","Effect of Intravenous Lidocaine Combined With Intratracheal Dexmedetomidine on Postoperative Throat Pain in Patients Undergoing Thyroid Cancer Surgery","Inclusion Criteria:\n\n* Thyroid cancer surgery with ASA grades I-II\n* Aged 18-65 years\n* The patient's communication is normal and they have a certain learning ability\n\nExclusion Criteria:\n\n* Severe respiratory and circulatory system diseases\n* There was bradycardia (HR \\\u003C 60 beats\u002Fminute) or atrioventricular block before the operation\n* Nervous system disease\n* Mental and psychological disorders\n* Abnormal liver and kidney functions\n* Pregnant and lactating women",{"count":110,"type":20},144,[23],"Objective: The present study was to investigate the effect of intravenous lidocaine combined with intratracheal dexmedetomidine on postoperative sore throat in patients undergoing thyroid cancer surgery.\n\nMethods: Investigators enrolled 144 patients with American Society of Anesthesiologists (ASA) physical status I and II, aged 18-65 years, and scheduled for elective undergoing thyroid cancer surgery with general anesthesia. The participants were randomly assigned into four groups(n=36 each group): Group L received lidocaine 1.5 mg\u002Fkg was injected intravenously 3 min before endotracheal intubation and tracheal spray with 0.8% ropivacaine 40 mg (5 mL) for surface anesthesia. Group D received equal volume normal saline was injected intravenously 3 min before tracheal intubation and tracheal spray with dexmedetomidine (1 μg\u002Fkg) mixed with 0.8% ropivacaine 40 mg (5 mL). Group LD received lidocaine 1.5 mg\u002Fkg was injected intravenously 3 min before endotracheal intubation and tracheal spray with dexmedetomidine (1 μg\u002Fkg) mixed with 0.8% ropivacaine 40 mg (5 mL). Group C received equal volume normal saline was injected intravenously 3 min before tracheal intubation and tracheal spray with 0.8% ropivacaine 40 mg (5 mL) for surface anesthesia.The incidence and severity of postoperative sore throat were recorded in four groups at 1 h, 2 h, 6 h, 24 h and 48 h after operation.",[114,115,59],"Dexmedetomidine","Lidocaine",[117,118,64,65],"dexmedetomidine","lidocaine","2025-04-28",{"date":121,"type":37},"2025-04-30",{"date":123,"type":20},"2025-04-25",{"date":125,"type":20},"2025-09-25",{"name":43,"class":44},{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":53,"minAge":16,"maxAge":17,"enrollmentInfo":134,"targetDuration":4,"studyType":21,"phases":136,"briefSummary":137,"conditions":138,"keywords":141,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":45},"100552190","deep-neuromuscular-block-affect-the-quality-of-recovery-after-laparoscopic-hysterectomy-100552190","NCT06469866","Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy","Effect of Deep Neuromuscular Block on the Quality of Recovery After Laparoscopic Hysterectomy","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status Ⅰ- Ⅲ\n* Scheduled for elective laparoscopic hysterectomy\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* BMI \\>35\n* Renal or hepatic insufficiency\n* History of preoperative psychiatric\n* Previous surgery at procedure site\n* Neuromuscular disease, pregnancy, and contraindications to study medications.",{"count":135,"type":20},72,[23],"BACKGROUND: Some studies have revealed that deep neuromuscular block (NMB) improve surgical conditions and alleviated postoperative pain compared with moderate NMB. The present study investigated deep NMB could improve the quality of recovery after laparoscopic hysterectomy\n\nMETHODS: seventy-two women with elective laparoscopic hysterectomy were randomly divided into 2 groups: Patients in group A received low-pressure pneumoperitoneum (LPP), which was set at 8-10 mmHg with deep NMB. Patients in group B received standard-pressure pneumoperitoneum (SPP), which was set at 12-14 mmHg with moderate NMB. Primary outcome was the quality of recovery (QoR-15) at 1 day after sugery. The secondary outcomes included postoperative pain, surgical condition, incidence of shoulder pain, the incidence of rescue analgesic drug use, cumulative dose of analgesics, time of first flatus, post-operative nausea and vomiting, time of tracheal tube removal.",[139,140],"Neuromuscular Blockade","Laparoscopy",[142,143,144],"Neuromuscular block","Recovery","Laparoscopic hysterectomy","2024-06-19",{"date":147,"type":37},"2024-06-24",{"date":149,"type":20},"2024-06-25",{"date":151,"type":20},"2024-11-25",{"name":43,"class":44},""]