[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Antonio Leidi\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100551854","investigating-acute-heart-failure-decongestion-guided-by-lung-ultrasonography-100551854",false,"NCT06465498","Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography","Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography (IcarUS) : a Randomized Controlled Trial","IcarUS","Inclusion Criteria:\n\n* ≥ 18 years old\n* Planned or actual admission to intermediate care units, general internal medical or cardiology wards\n* Diagnosis of congestive AHF on admission chart (primary or secondary diagnosis)\n* Raised value of N terminal-pro-brain natriuretic peptide (≥1000 ng\u002Fl).\n\nKey Exclusion Criteria:\n\n* Known isolated right heart failure\n* Systolic blood pressure \\\u003C90 mmHg, mean arterial pressure \\\u003C65 mmHg at the moment of inclusion\n* The following conditions mimicking lung cardiogenic oedema on LUS if known at inclusion and documented: Interstitial lung disease, lung cancer or metastasis, acute respiratory distress syndrome, pulmonary contusion\n* Known virologically confirmed SARS-CoV-2 pneumonia in the preceding 3 months\n* Unwillingness to give consent\n* Subjects who are pregnant or breastfeeding\n* Hospitalisation for palliative care and probable end-life within 30 days","ALL","18 Years",{"count":20,"type":21},222,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to investigate whether a lung ultrasonography (LUS)-guided decongestion strategy in adults hospitalized for acute heart failure (AHF) can improve patient-centered outcomes.\n\nThe main questions it aims to answer are:\n\n* Does this strategy shorten the length of stay and reduce early hospital readmissions?\n* Does this strategy improve patients' symptoms and quality of life ?\n\nResearchers will compare LUS to physical examination (PE).",[27],"Acute Heart Failure",[29,30,31,32,33],"Lung ultrasonography","Ultrasound","Point-of-care ultrasonography","Decongestion","Diuretic","RECRUITING","2026-03-26",{"date":37,"type":38},"2026-04-01","ACTUAL",{"date":40,"type":38},"2024-10-22",{"date":42,"type":21},"2027-04-30",{"name":44,"class":45},"Antonio Leidi","OTHER",5,""]