[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Appalachian State University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":85},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":4},"100624764","telehealth-music-therapy-for-adults-with-endocrine-disorder-and-depression-100624764",false,"NCT07413874","Telehealth Music Therapy for Adults With Endocrine Disorder and Depression","Telehealth Music Therapy for Adults With Endocrine System Based Autoimmune Disease and a Depressive Disorder: An Intervention Development Study","Inclusion Criteria:\n\n* self-reported depression\n* self-reported autoimmune endocrine disease\n* 18-65 years of age\n* have a device that supports the Zoom platform (camera and audio)\n\nExclusion Criteria:\n\n* intellectual or developmental disability\n* no auto-immune disease\n* no depression\n* lack of access to device\n* under the age of 18 years\n* over the age of 65 years","ALL","18 Years","65 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to explore if a telehealth music therapy intervention helps with quality of life, depression symptoms, anxiety symptoms. It will also explore the participants' relationship to music. The main questions it aims to answer are:\n\n* Refine and tailor the music therapy intervention to fit the specific needs of adults living with an autoimmune disease and depression.\n* Examine the feasibility of the study protocol to support a future full-scale trial\n* Examine how music therapy impacts quality of life, depression symptoms, and anxiety symptoms\n* Explore how music therapy impacts one's relationship to music\n\nParticipants will:\n\n* have a short interview where you'll fill out a questionnaire with some basic information, answers about your depression, quality of life, and potential anxiety, and a question about how you feel about music at the start and end of the sessions\n* attend 8 weekly sessions, approximately 30-45 minutes each, with a board certified music therapist over telehealth\u002FZoom\n* answer a few questions about the music therapy intervention",[27,28,29,30,31,32,33],"Type 1 Diabetes","Hashimoto Disease","Graves Disease","Addison Disease","Autoimmune Polyglandular Syndrome Type III","Depression","Endocrine System Diseases",[35,36,37,38,39,40,41,42],"type 1 diabetes","music therapy","behavioral health","psychosocial","diabetes","behavioral intervention","quality of life","telehealth","NOT_YET_RECRUITING","2026-02-10",{"date":46,"type":47},"2026-02-17","ACTUAL",{"date":49,"type":21},"2026-02-01",{"date":51,"type":21},"2026-12-31",{"name":53,"class":54},"Appalachian State University","OTHER",{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":16,"minAge":18,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},"100554138","cognition-flavonoids-exercise-gut-microbiome-100554138","NCT06495190","Cognition, Flavonoids, Exercise, Gut Microbiome","Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut Microbiome","Inclusion Criteria:\n\n* Score on the Montreal Cognitive Assessment (MoCA test) of 24.1-25.2 that indicates mild cognitive decline. The MoCA test score ranges from 0 to 30, with higher scores from 26 to 30 considered normal.\n* Healthy, non-smoking male or female participants 65 to 85 years of age.\n* Capable of engaging in a supervised 12-week exercise training program (brisk walking or stretching).\n* Physically inactive (defined as less than 150 min\u002Fweek moderate or less than 75 minutes vigorous aerobic and\u002For resistance exercise during the past 4 weeks).\n* Willingness to be randomized to one of four groups.\n* Willingness to provide blood, urine, and fecal samples (3 each),\n* Willingness to avoid blueberry intake during the 12-weeks study (other than what is provided through the study).\n* Willingness to maintain current diet and physical activity patterns during the study (other than what is prescribed as a part of the study), and make no formal attempts to lose or gain body weight.\n* Willingness to be a participant in this study only and not enter any other studies.\n\nExclusion Criteria:\n\n* Allergy to blueberries.\n* Diagnosis of Type I or Type 2 diabetes.\n* Chronic cardiovascular, metabolic, or renal condition that is uncontrolled (controlled defined as stable for 6 months or more).\n* History of signs or symptoms during rest or physical activity such as chest discomfort, unreasonable breathlessness, dizziness, fainting, or blackouts.\n* Use of any prescription or over-the-counter drug intended to support cognition or with known cognitive side effects.\n* Any other concurrent condition or use of medications or supplements which, in the opinion of the study clinician would preclude participation in this study.\n* Diagnosis of dementia.",true,"85 Years",{"count":65,"type":21},240,[24],"This NIH project will examine the effects of routine flavonoid-rich blueberry intake (12-weeks), combined with or in the absence of regular moderate exercise, on cognitive function in a clinical population of older participants identified as experiencing age-related cognitive changes. This project's hypothesis is that the combination of flavonoid-rich diet and routine physical activity may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the gut microbiome.",[69],"Cognitive Decline, Mild",[71,72,73,74],"aging","flavonoids","exercise","gut microbiome","RECRUITING","2025-03-07",{"date":78,"type":47},"2025-03-12",{"date":80,"type":47},"2025-01-01",{"date":82,"type":21},"2028-12-31",{"name":53,"class":54},1,""]