[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":69},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100614139","role-of-alprazolam-in-management-of-post-endodontic-pain-after-single-visit-root-canal-treatment-to-compare-mean-pain-score-between-two-group-of-participants-undergoing-post-operative-pain-management-after-single-visit-root-canal-treatment-nsaids-alone-and-a-combination-of-nsaids-and-alprazolam-100614139",false,"NCT07275710","Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment. To Compare Mean Pain Score Between Two Group of Participants Undergoing Post Operative Pain Management After Single Visit Root Canal Treatment: NSAIDs Alone and a Combination of NSAIDs and Alprazolam.","Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment","Inclusion Criteria:\n\n* patients aged between 18-60 years\n* healthy patients with ASA classification I and II\n* Teeth with symptomatic irreversible pulpitis\n\nExclusion Criteria:\n\n* patient suffering from systemic disease that requires antibiotics\n* pregnant or lactating mothers\n* teeth with periapical radiolucency\n* teeth with severe periodontitis\n* patients who have taken analgesics 12 hours prior to procedure\n* patients already taking benzodiadepines","ALL","18 Years","60 Years",{"count":20,"type":21},110,"ESTIMATED","INTERVENTIONAL",[24],"NA","To compare mean pain score between two group of participants undergoing post operative pain management after single visit root canal treatment: one group receiving NSAIDs alone and the other receiving a combination of NSAIDs and an anxiolytic medication i.e alprazolam.",[27],"Pain",[29,30,31],"post endodontic pain","root canal treatment","alprazolam","NOT_YET_RECRUITING","2025-12-07",{"date":35,"type":36},"2025-12-10","ACTUAL",{"date":38,"type":21},"2026-02-01",{"date":40,"type":21},"2027-02-01",{"name":42,"class":43},"Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":67,"leadSponsor":68,"locationsCount":44},"100615252","this-study-compares-two-different-ways-of-cleaning-and-shaping-root-canals-during-root-canal-treatment-the-step-down-technique-and-the-step-back-technique-iu-want-to-find-out-which-method-causes-less-pain-after-the-procedure-patients-will-be-randomly-placed-into-one-of-the-two-groups-treated-wit-100615252","NCT07290192","This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit","Comparison of Impact of Step Down Verses Step Back Preparation Technique of Root Canals on Post Operative Pain in Patients Having Pulp Necrosis","Inclusion Criteria:\n\n* patients age between 18 to 65 years Healthy patients with ASA classification 1 and 2 Patients of both genders Patients who agreed to attend recall appointments Patients having single rooted tooth with pulp necrosis without pre-existing periapical pathosis and apical periodontitis\n\nExclusion Criteria:\n\n* Patients with history of chronic pain Previously RCT treated tooth Teeth with apical pathosis ,with irreversible pulpitis Patients having systemic illness Multirooted teeth Patients consumed analgesics between appointments Teeth with calcified canals Cases of root fracture Children Pregnant and lactating mothers Smokers","65 Years",{"count":20,"type":21},[24],"This randomized clinical trial aims to compare the step-back and step-down root canal preparation techniques in patients with pulp necrosis. The study will evaluate which technique results in less postoperative pain. Participants will be randomly assigned to one of the two groups. Pain intensity will be recorded at specific time points after the procedure using a standardized pain scale. The goal is to identify the technique that provides better patient comfort after root canal treatment.This study is a randomized clinical trial designed to compare the effects of two root canal preparation techniques-step-back and step-down-on postoperative pain in patients diagnosed with pulp necrosis. Participants will be randomly assigned to one of the two groups.",[57],"Pulp Necrosis",[59,60,61,62],"Post operative pain","Pulp necrosis","Step back technique","Step down technique","2025-12-06",{"date":65,"type":36},"2025-12-18",{"date":38,"type":21},{"date":40,"type":21},{"name":42,"class":43},""]