[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Aroa Biosurgery Limited\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":85},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100622568","phase-4-combined-ofm-and-vacuum-assisted-therapy-for-expedited-regeneration-over-structures-100622568",false,"NCT07385313","Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures","Randomized Prospective Evaluation of Ovine Forestomach Matrix (OFM) and NPWT to Accelerate Tissue Coverage Over Exposed Structures","COVER","Inclusion Criteria:\n\n* Patients will be considered eligible for the study based on the following criteria:\n\n  * Willing and able to provide written informed consent and to comply with the requirements of the Clinical Investigational Plan\n  * Male or female patients aged 18 years or above\n  * Patient is requiring reconstruction of a full thickness soft tissue defect, that includes exposed structures (bone, tendon, or neurovascular), upper or lower extremity.\n  * Total defect size, range 25 to 800 cm2\n\nExclusion Criteria:\n\n* Patients will be excluded from the study based on the following criteria:\n\n  * Patients with known sensitivity to ovine (sheep) derived material\n  * Pregnant or lactating females.\n  * Patients who are prisoners.\n  * Patients who are likely not to complete the study.\n  * Patients who, in the opinion of the Investigator, are unlikely to comply with the protocol.\n  * Patients currently participating in or have participated in another clinical study within the past 30 days prior to enrolment that at the discretion of the Investigator makes them unsuitable for inclusion in the study.\n  * Any subject who, at the discretion of the Investigator, is not suitable for inclusion in the study.\n  * Any medical condition, recent treatment or serious intercurrent illness that, in the opinion of the Investigator, may make it undesirable for the patient to participate in the study.\n  * Obesity (BMI\\>45)\n  * Blood glucose ≥350 mg\u002FdL at admission\n  * History of chronic peripheral vascular disease\n  * Current immunosuppression\n  * Recent neoadjuvant chemotherapy or radiotherapy\n  * Previous or concurrent application of a cell\u002Ftissue-based product (CTP, or skin substitute) at the wound site within 30 days of the Screening Visit\n  * Defect is a third degree burn","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Demonstrate faster tissue coverage of exposed structures using OFM in combination with negative pressure wound therapy (NPWT), versus NPWT alone",[27,28,29],"Soft Tissue Defects","Soft Tissue Wounds","Traumatic Soft Tissue Defect",[31,32,33,34,35],"Traumatic Wounds","Soft Tissue Repair","Negative Pressure Wound Therapy","Ovine Forestomach Matrix","Wound Healing","RECRUITING","2026-04-09",{"date":39,"type":40},"2026-04-13","ACTUAL",{"date":42,"type":40},"2026-03-31",{"date":44,"type":21},"2027-04",{"name":46,"class":47},"Aroa Biosurgery Limited","INDUSTRY",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":69,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},"100458003","myriad-augmented-soft-tissue-reconstruction-registry-100458003","NCT05243966","Myriad™ Augmented Soft Tissue Reconstruction Registry","Registry of Myriad™ Utilization in Soft Tissue Reconstruction Procedures","MASTRR","Inclusion Criteria:\n\n* Willing and able to provide written informed consent and to comply with the requirements of Clinical Investigational Plan\n* Male or female patients aged 18 years or above\n* Patients where Matrix and\u002For Morcells were used as part of their soft tissue reconstruction procedure\n* Subject that are willing and able to comply with all aspects of the treatment and evaluation schedule\n\nExclusion Criteria:\n\n* Patients with known sensitivity to ovine (sheep) derived material\n* Patients with full thickness ('third degree') burns\n* Patients with wounds with uncontrolled clinical infection (CDC Contamination Grade=4)\n* Any medical condition or serious intercurrent illness that, in the opinion of the investigator, may make it undesirable for the patient to participate in the study\n* Patient is currently participating or has participated in another clinical study within past 30 days prior to enrollment\n* Pregnant or lactating women\n* Any subject who, at the discretion of the Investigator, is not suitable for inclusion in the study",{"count":57,"type":21},800,"12 Months","OBSERVATIONAL","This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures. The study will enroll participants who are undergoing a surgical procedure, where the attending physician will use Myriad™ as part of the surgical intervention.",[62,63,64,65,66,67,68],"Abdominal Wound Dehiscence","Necrotizing Soft Tissue Infection","Lower Extremity Wound","Pilonidal Sinus","Anal Fistula","Hidradenitis Suppurativa","Pressure Injury",[70,71,72,73,74,75],"Soft tissue reconstruction","Limb salvage","Extracellular matrix","Soft tissue reinforcement","Wound reconstruction","Regenerative medicine","2026-02-17",{"date":78,"type":40},"2026-02-19",{"date":80,"type":40},"2022-01-10",{"date":82,"type":21},"2029-01",{"name":46,"class":47},13,""]