[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Artialis\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100554729","setting-up-a-cohort-of-patients-with-inflammatory-bowel-disease-and-a-cohort-of-patients-without-chronic-inflammatory-bowel-disease-100554729",false,"NCT06502873","Setting up a Cohort of Patients With Inflammatory Bowel Disease and a Cohort of Patients Without Chronic Inflammatory Bowel Disease","Setting up a Cohort of Patients With Inflammatory Bowel Disease and a Cohort of Patients Without Chronic Inflammatory Bowel Disease in the Context of the Translational Study of Biomarkers of Intestinal Dysbiosis (ELITE Walloon Project)","ELITE","Inclusion Criteria:\n\nGeneral criteria:\n\n* Male or female ≥ 18 years old\n* Able to follow the instructions of the study\n* Having signed an informed consent\n\nSpecific for Crohn cohort:\n\n* A confirmed diagnosis of IBD\n* Rectal or colonic or ileocolic involvement\n* Patients with CD presenting inflammatory flare and disease extent in the colon or ileocolic region with:\n* A clinical activity defined by an average of four or more instances of very soft or liquid stools daily or an abdominal pain score of 2 or more OR a CDAI (CD Activity Index) ≥ 220 OR a Harvey-Bradshaw Index \\> 8 OR a faecal calprotectin ≥ 250 µg\u002Fg And\n* A endoscopic activity defined by a SES-CD (Simple Endoscopic Score for Crohn Disease) ≥ 6 or a CDEIS (CD Endoscopic Index score) ≥ 7\n* Patients with UC presenting inflammatory flare with:\n\nA clinical activity defined by a modified Mayo score ≥ 3 OR a Simple Clinical Colitis Activity Index ≥5 OR Patient Reported Outcome (PRO2) ≥ 4 with a subscore of rectal bleeding ≥1 OR a faecal calprotectin ≥ 250 µg\u002Fg AND An endoscopic activity defined by a Mayo endoscopic sub-score ≥ 2\n\nSpecific for Control cohort:\n\nPatient with no colonic lesion(s) visible during the endoscopical examination (neither Crohn's nor other colitis nor cancer)\n\nExclusion Criteria:\n\nGeneral criteria:\n\n* Commercial Pharmaceutical probiotic administration within the previous month\n* Treatment with antibiotics (whatever the route of administration) within last 3 months\n* Non-remission Cancer or in remission for less than 6 months\n* Any contraindication to colonoscopy and\u002For biopsy, left to PI discretion\n* Under guardianship or judiciable protection\n* Pregnant or breastfeeding women\n* Currently participating or having participated in the last 3 months to a clinical study with investigational medicine or food supplement\n\nSpecific for Crohn cohort:\n\n* Crohn disease localized only in Ileum\n* Inflammatory colon pathology other than Crohn's (infectious, drug-induced,…)","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The objective of this study is to constitute cohorts of IBD versus non-IBD patients to identify (a) new biomarker(s) of intestinal dysbiosis associated with inflammatory bowel disease, and develop a prototype for assaying such marker(s) in blood.",[27],"Inflammatory Bowel Disease (IBD)",[29,30,31],"cohort","BEV","intestinal dysbiosis","RECRUITING","2026-01-27",{"date":35,"type":36},"2026-01-28","ACTUAL",{"date":38,"type":36},"2024-06-28",{"date":40,"type":21},"2026-12-31",{"name":42,"class":43},"Artialis","INDUSTRY",""]