[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Association Clinique Thérapeutique Infantile du val de Marne\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":274},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,43,65,87,108,137,165,191,220,243],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100413512","national-non-interventional-study-of-invasive-pneumococcal-disease-in-children-and-newborns-100413512",false,"NCT04664556","National, Non Interventional Study of Invasive Pneumococcal Disease in Children and Newborns","Population-based Nationwide Study on Invasive Pneumococcal Infections Among Children (0-18 Years) in France","IPD","Inclusion Criteria:\n\n* Isolate of Streptococcus pneumoniae from at least one blood culture, or pleural fluid, or joint fluid, or cerebrospinal fluid or other normally sterile body site, or if there is a positive blood polymerase chain reaction (PCR).\n\nExclusion Criteria:\n\n* Pneumococcal strain not transmetted to National Reference Center for Pneumococci or to Regional Pneumococci Observatory","ALL","1 Day","18 Years",{"count":21,"type":22},2500,"ESTIMATED","OBSERVATIONAL","After 7 then 13 valent pneumococcal conjugate vaccine (PCV) implementation in France in children, we will evaluate the impact of this vaccination on invasive pneumococcal disease (IPD). We will describe the clinical characteristics of IPD, pneumococcus serotyping, underlying conditions and vaccination status.",[26,27,28,29],"Pneumococcal Infections","Pneumococcal Conjugate Vaccine","Antibiotic Treatment","Mortality","RECRUITING","2026-04-23",{"date":33,"type":34},"2026-04-28","ACTUAL",{"date":36,"type":34},"2010-12-13",{"date":38,"type":22},"2030-01-01",{"name":40,"class":41},"Association Clinique Thérapeutique Infantile du val de Marne","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":60,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":64,"locationsCount":42},"100413513","national-bacterial-meningitis-study-in-children-and-newborns-100413513","NCT04664569","National Bacterial Meningitis Study in Children and Newborns","National Observatory of Bacterial Meningitis in Children and Newborns","Inclusion Criteria:\n\n* clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and\u002For positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and\u002For positive CSF polymerase chain reaction (PCR), and\u002For positive blood culture with CSF pleocytosis (\\> 10 cells\u002FµL).\n* purpura fulminans\n\nExclusion Criteria:\n\n\\-",{"count":51,"type":22},10000,"Bacterial meningitis is a major cause of morbidity and mortality in childhood. Antibiotic treatment recommendations are based on epidemiological and susceptibility data. The epidemiology of bacterialméningitis has changed in recent years, mainly owing to widespread use of different conjugate vaccines. The aim of this prospective national survey is to describe epidemiology of bacteria implicated in bacterial meningitis in children.",[54,55,27,56,57,58,28,59],"Meningitis","Children, Only","Meningococcal Vaccines","H. Influenzae Vaccine","Neonatal Infection","Case Fatality Rate",{"date":33,"type":34},{"date":62,"type":34},"2001-01-01",{"date":38,"type":22},{"name":40,"class":41},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":75,"conditions":76,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":42},"100630302","national-observatory-of-children-hospitalized-with-bronchiolitis-100630302","NCT07485907","National Observatory of Children Hospitalized With Bronchiolitis","OVNI3","Inclusion Criteria:\n\n* Children under 12 months\n* Treated at one of the 12 study sites\n* From October 15, 2025 to February 15, 2026\n* For acute bronchiolitis defined according to current national and international recommendations\n* Hospitalized\n\nand\n\n* RSV testing\n* Known nirsevimab immunization status for the ongoing 2025\u002F2026 season\n\nExclusion Criteria:\n\n* Refusal to participate by the legal representative\n* Maternal immunization with abrysvo after September 1st 2025","12 Months",{"count":74,"type":22},1000,"OVNI3 is multicenter, non-interventional study based on the analysis of retrospective patient data extracted from medical records and collected as part of routine clinical care following hospitalization for bronchiolitis",[77],"Bronchiolitis","NOT_YET_RECRUITING","2026-03-17",{"date":81,"type":34},"2026-03-20",{"date":83,"type":22},"2026-03-15",{"date":85,"type":22},"2027-03-15",{"name":40,"class":41},{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":19,"enrollmentInfo":95,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":107,"locationsCount":42},"100536093","communautary-pediatric-bacterial-infection-in-intensive-care-unit-100536093","NCT06260345","CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit","Observatory of Pediatric Severe Communautary Bacterial Infections","CAPRICE","Inclusion Criteria:\n\n* Age \\\u003C18 years (only hospitalized children)\n* Severe communautary bacterial infection defined by hospitalization in a pediatric intensive care unit (documentation of infection by identification of the bacteria in a sterile environment).\n\nExclusion Criteria:\n\n* Refusal by one of the parents or by Child in understanding age\n* Nosocomial infection",{"count":96,"type":22},3000,"Severe bacterial infections are a worldwide scourge. However, the epidemiology of this type of infection varies over time. It is therefore essential to monitor them in order to prevent them more effectively. At this time, in France, no monitoring exists for this kind of infections.",[99,100,101],"Hospitalized Children","Severe Infection","Invasive Bacterial Infection",{"date":103,"type":34},"2026-03-19",{"date":105,"type":34},"2024-01-01",{"date":38,"type":22},{"name":40,"class":41},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":115,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":131,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":42},"100424496","bacteriological-evaluation-of-children-with-otorrhea-100424496","NCT04807660","Bacteriological Evaluation of Children With Otorrhea","Bacteriological Evaluation of Spontaneous Otorrhea in Children","Inclusion Criteria:\n\n* children from 3 months to 15 years old\n* with otorrhea\n* signed parents consent\n\nExclusion Criteria:\n\n* children under 3 months\n* children \\> 15 years old","3 Months","15 Years",{"count":118,"type":22},1500,"After pneumococcal conjugate vaccine implementation, the number of acute otitis media (AOM) episodes has decreased, but AOM still remains among the most common diagnoses in childhood. From 2% to 17% of cases of AOM feature spontaneous perforation of the tympanic membrane (SPTM). The aim of this study was to describe the bacteriological causes of SPTM several years after PCV13 implementation, in 2010.",[121],"Otorrhea",[123,124,125,126,127,128,129,130],"otorrhea","children","spontaneous perforation of the tympanic membrane","ambulatory","streptococcus pneumoniae","heamophilus influenzae","moraxella catarrhalis","streptococcus pyogenes",{"date":103,"type":34},{"date":133,"type":34},"2015-10-01",{"date":135,"type":22},"2028-10-31",{"name":40,"class":41},{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":145,"enrollmentInfo":146,"targetDuration":4,"studyType":148,"phases":149,"briefSummary":151,"conditions":152,"keywords":156,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":159,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":42},"100419583","rsv-burden-in-outpatient-and-hospital-settings-100419583","NCT04743609","RSV Burden in Outpatient and Hospital Settings","Ambulatory Respiratory Tract Infection Survey, Burden of Respiratory Syncitial Virus in the Era of Covid-19","Oursyn","Inclusion Criteria:\n\n* children under 24 months of age (≤)\n* One of the holders of parental authority signed the consent\n* Patient affiliated to a social security scheme (Social Security or Universal Medical Coverage)\n* Acute purulent otitis media (Paradise Criteria) or otorrhea with or withitout associated bronchiolitis\n\nExclusion Criteria:\n\n* Age \\>24 months\n* Refusal by one of the parents\n* Not affiliated to a social security system\n* Maternal RSV vaccination during the pregnancy of the included child","24 Months",{"count":147,"type":22},1900,"INTERVENTIONAL",[150],"NA","Strengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)",[153,55,154,155],"RSV Infection","Outpatient","Otitis",[157,124,158],"RSV","otitis with or without concomitant bronchiolitis",{"date":103,"type":34},{"date":161,"type":34},"2021-02-08",{"date":163,"type":22},"2026-12-08",{"name":40,"class":41},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":172,"sex":17,"minAge":173,"maxAge":116,"enrollmentInfo":174,"targetDuration":4,"studyType":148,"phases":176,"briefSummary":177,"conditions":178,"keywords":181,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":185,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":42},"100397837","nasopharyngeal-carriage-of-s-pneumoniae-100397837","NCT04460313","Nasopharyngeal Carriage of S. Pneumoniae","Observatory of Streptococcus Pneumoniae Nasopharyngeal Carriage in Infants With Acute Otitis Media (AOM) and in Healthy Children\"","children seen on an outpatient\n\nInclusion Criteria:\n\n* both sexes\n* suffering from suppurative AOM or healthy children\n\n  * age: 6 months to 36 months for AOM\n  * age: 6 months to 15 years for healthy children\n* informed consent from parents or guardians\n* Children who haven't received antibiotic treatment within 7 days before enrollment,\n\nExclusion Criteria:\n\n* severe underlying disease,\n* inclusion in the study during the previous 12 months\n* Children with bullous myringitis cannot be included.",true,"6 Months",{"count":175,"type":22},25760,[150],"This nasopharyngeal (NP) carriage surveillance study was requested by the European Agency for the Evaluation of Medicinal Products as a post-licensing commitment to determine whether the use of the pneumococcal conjugate vaccines (PCVs) including 7 then 13 valents (introduced in 2001 and 2010, respectively) caused a shift in the distribution of Streptococcus pneumoniae serotypes in children with acute otitis media and modified the resistance of this bacterial species to antibiotics.",[179,55,180],"Nasopharyngeal Carriage","Antibiotic Resistant Strain",[182,183,184],"Pneumococcal conjugate vaccine","Streptococcus pneumoniae","Carriage",{"date":103,"type":34},{"date":187,"type":34},"2001-09-11",{"date":189,"type":22},"2026-12-31",{"name":40,"class":41},{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":199,"enrollmentInfo":200,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":42},"100499869","invasive-group-a-streptococcal-infection-100499869","NCT05788861","Invasive Group A Streptococcal Infection","French Pediatric Nationwide Observatory of Invasive Group A Streptococcal Infection (in Childen for 0 to 18 Ages)","ISAI","Inclusion Criteria:\n\n* Age\\\u003C18 years\n* Documented invasive Group A Streptococcus infection (identification of GAS in a normally sterile site or from another site in case of toxin shock or necrotizing dermo-hypodermatitis)\n\nExclusion Criteria:\n\n* Opposition of the patient or his\u002Fher legal representative","17 Years",{"count":201,"type":22},100,"This study is observational, retrospective and prospective study in pediatric patients hospitalized with invasive streptococcal A infection",[204,205,100,206,207,208,209,210,211],"Sepsis Due to Streptococcus, Group A","Risk Factors","Medical Care","Medical Complications","Outcome, Fatal","Therapy","Strain","Virulence Factors","2024-02-07",{"date":214,"type":34},"2024-02-08",{"date":216,"type":34},"2022-09-01",{"date":218,"type":22},"2026-09-01",{"name":40,"class":41},{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":228,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":230,"conditions":231,"keywords":234,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":238,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":242,"locationsCount":42},"100424500","pediatric-pertussis-in-ambulatory-settings-100424500","NCT04807712","Pediatric Pertussis in Ambulatory Settings","National Surveillance of Pediatric Pertussis in Ambulatory Settings","ACTIVCOQ","Inclusion Criteria:\n\n* All children under 18 years old with a pertussis diagnosis is suspected and a biological exam is requested\n\nExclusion Criteria:\n\n* children without symptoms with a household confirmed case\n* cases for which the pertussis diagnosis was not suspected by the pediatrician",{"count":229,"type":22},898,"Since 2002, Whooping cough surveillance in pediatric private practice has been set up in France. The results of the first years, 2002-2006, have confirmed the effectiveness of the Pertussis whole-cell (Pw) vaccine and in particular the duration of protection of 9\u002F10 years. After evaluating cases in children vaccinated with Pw vaccines, the study aims today to analyze cases in children vaccinated with Pertussis acellular (Pa) vaccines used since 2002\u002F2003 and to assess, on an outpatient basis, the impact of new vaccine recommendations in France (in 2013, introduction of a 2 + 1 schedule - 8 weeks, 4 months and a 11-month recall - and a 6-year recall, and in 2014, update in the recommendations of exams to be prescribed based on the child's age and vaccination status).",[232,55,233],"Pertussis\u002FWhooping Cough","Ambulatory",[235,236,237],"Pertussis","surveillance","pertussis acellular vaccine",{"date":214,"type":34},{"date":240,"type":34},"2001-05-30",{"date":38,"type":22},{"name":40,"class":41},{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":248,"acronym":249,"eligibilityCriteria":250,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":251,"enrollmentInfo":252,"targetDuration":254,"studyType":23,"phases":4,"briefSummary":255,"conditions":256,"keywords":262,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":268,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":42},"100398696","pediatric-and-ambulatory-research-in-infectious-diseases-100398696","NCT04471493","Pediatric and Ambulatory Research in Infectious Diseases","Real Time Surveillance of Pediatric Infectious Diseases in French Ambulatory Care: PARI Study","PARI","Inclusion Criteria:\n\n* Children under 16 years of age with at least one infectious disease among:\n* pharyngitis\n* otitis\n* pneumonia\n* influenza\n* bronchiolitisz\n* varicella\n* gastroenteritis\n* enterovirus disease\n* bordetella pertussis disease\n* using the same same software, Axi5-Infansoft (developed by CompuGroup Medical, Nanterre, France)\n\nExclusion Criteria:\n\n* parental refusal","16 Years",{"count":253,"type":22},400000,"5 Years","Many ambulatory networks are mainly based on diagnoses made by first-line physicians not specifically trained to join the network. Here we aim to set up a surveillance network on pediatric infectious diseases with an investment in teaching with specific trainings of participating pediatricians, increasing in use of point of care tests, and automated data extraction from the computers of the pediatricians.",[155,77,257,258,259,260,261],"Influenza","Pharyngitis","Varicella","Pneumonia","Gastroenteritis",[263,264,265,266,267],"Vaccination","Antibiotic treatment","Point of care test","automated data extraction","network",{"date":214,"type":34},{"date":270,"type":34},"2017-06-26",{"date":272,"type":22},"2030-08-02",{"name":40,"class":41},""]