[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Austral Diagnostics\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100642257","contactless-ultrasound-data-acquisition-in-emergency-departments-to-discriminate-the-origin-of-dyspnea-and-chest-pain-100642257",false,"NCT07653204","Contactless Ultrasound Data Acquisition in Emergency Departments to Discriminate the Origin of Dyspnea and Chest Pain","Prospective Study for Data Acquisition in Emergency Departments to Develop a Discrimination Algorithm for the Origin of Dyspnea and Chest Pain Using the ADx-One Medical Device","PAnDA-One","Inclusion Criteria:\n\n* Presentation to the emergency department for one or more of the following symptoms of less than 14 days' duration: acute non-traumatic dyspnea, or recent worsening of chronic dyspnea, or non-traumatic chest pain.\n* Patient able to sit on a chair or on the edge of the bed\n* Affiliation to national health insurance\n* Able to receive study information, understand the study, and provide written informed consent\n\nExclusion Criteria:\n\n* • Immediate need for life-saving intervention or clinical instability incompatible with study procedures.\n\n  * Shock or severe hemodynamic instability, for example systolic blood pressure \\\u003C90 mmHg for at least 30 minutes or associated signs of hypoperfusion.\n  * Altered mental status or any condition preventing provision of valid informed consent.\n  * Known cognitive impairment preventing informed consent.\n  * Transfer to another care site before the ADx-One acquisition can be performed.\n  * Known pregnancy\n  * Minor, legally protected adult, or person deprived of liberty.\n  * Participation in another interventional clinical study judged incompatible with this study.","ALL","18 Years",{"count":20,"type":21},2500,"ESTIMATED","OBSERVATIONAL","PAnDA-One is a prospective, multicenter, interventional study (10 centers, France) aimed at developing and validating a diagnostic support algorithm based on the ADx-One medical device, which non-invasively acquires thoracic vibrations using airborne ultrasound.\n\nThe study will enroll 2,500 patients presenting to the emergency department with acute dyspnea or non-traumatic chest pain, divided into a development cohort (N = 1,500) and an independent test cohort (N = 1,000). The deep learning algorithm will be trained to discriminate cardiovascular from non-cardiovascular origins of symptoms, and its performance will be assessed by AUROC, sensitivity, and specificity against a final diagnosis established by an expert adjudication committee.\n\nPatient management will not be modified by study participation.",[25,26],"Dyspnea","Chest Pain",[28,29,30,31,32],"airborne ultrasound","dyspnea","chest pain","emergency department","algorithm","NOT_YET_RECRUITING","2026-06-15",{"date":36,"type":37},"2026-06-17","ACTUAL",{"date":39,"type":21},"2026-09",{"date":41,"type":21},"2027-05",{"name":43,"class":44},"Austral Diagnostics","INDUSTRY",""]