[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Azienda ULSS 8 Berica\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":91},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,63],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":62},"100630843","hands-on-vs-hands-off-techniques-in-perineal-protection-100630843",false,"NCT07492940","Hands-on vs Hands-off Techniques in Perineal Protection","The Midwife's Hands Between Waiting and Support: Hands-off vs hands-on Techniques in Manual Perineal Protection.","MPP","Criteri di inclusione:\n\n* Donne incinte nullipare o multipare\n* Gravidanza a termine\n* Feto nella presentazione cefalica\n* Consegna eutocic (spontanea)\n* Uso di ossitocina\n* Uso di analgesici\n\nCriteri di esclusione:\n\n* Parto prematuro: prematuro tardivo -Disagio fetale acuto durante la fase di espulsione-\n* Consegna della gretta\n* Distocia della spalla\n* Parto chirurgico (uso del vuoto ostetrico, manovra di Kristeller, taglio cesareo) --Episiotomia","FEMALE","18 Years",{"count":20,"type":21},737,"ESTIMATED","OBSERVATIONAL","Perineal tears are frequent during vaginal delivery. This study evaluates the impact of hands-on versus hands-off techniques on perineal and neonatal outcomes to determine the most effective protective strategy.",[25,26,27,28],"Perineal Trauma","Hands-on Technique","Hands-of Technique","Manual Perineal Protection",[30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49],"Perineal trauma","Perineal injury","Perineal lacerations","Perineal tears","Obstetric anal sphincter injuries","OASIS","Genital tract trauma","Labial lacerations","Labial tears","Vaginal tears","Pelvic floor muscle injury","Levator ani muscle avulsion","First-degree perineal tear","Second-degree perineal tear","Third-degree perineal tear","Fourth-degree perineal tear","hands on","hands off","hands-on technique","hands-off technique","RECRUITING","2026-03-20",{"date":53,"type":54},"2026-03-25","ACTUAL",{"date":56,"type":21},"2026-03-05",{"date":58,"type":21},"2027-03",{"name":60,"class":61},"Azienda ULSS 8 Berica","OTHER",1,{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":11,"sex":70,"minAge":18,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":50,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},"100626520","optimal-time-for-reperfusion-in-acute-pulmonary-embolism-100626520","NCT07436702","Optimal Time for Reperfusion in Acute Pulmonary Embolism","OPTIRAPE","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients with a diagnosis of intermediate-high or high pulmonary embolism confirmed by computed tomography pulmonary angiography (CTPA), pulmonary angiography, or echocardiography (evidence of a floating thrombus in the right atrium or right ventricle, or proximal visualization of thrombus in the pulmonary artery).\n* Classified as high-risk or intermediate-high-risk according to the 2019 European Society of Cardiology guidelines.\n* Provision of informed consent for the processing of personal data.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Patients in whom a diagnosis of acute high-risk or intermediate-high-risk pulmonary embolism has been excluded.\n* Inability to provide informed consent.","ALL",{"count":72,"type":21},500,"Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality worldwide. Current guidelines recommend early reperfusion for high-risk and intermediate-high-risk PE, yet systemic thrombolysis and percutaneous therapies are frequently underutilized, and no specific timing for reperfusion is defined, unlike in acute myocardial infarction or ischemic stroke. As most PE-related in-hospital deaths occur within the first hours and thrombus composition changes over time, defining an optimal reperfusion time window may improve survival and prevent hemodynamic deterioration. We therefore propose a national, multicenter, prospective observational study to evaluate the prognostic impact of reperfusion timing, using systemic thrombolysis or catheter-directed therapies, on in-hospital mortality and haemorrhagic or cardiovascular complications.",[75,76],"Pulmonary Embolism (Diagnosis)","Pulmonary Embolism Acute",[78,79,80,81],"Fibrinolysis","Anticoagulation","Catheter-directed treatments","Time of Reperfusion","2026-03-01",{"date":84,"type":54},"2026-03-03",{"date":86,"type":54},"2025-11-25",{"date":88,"type":21},"2026-10-30",{"name":60,"class":61},7,""]