[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Azienda Usl di Bologna\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":315},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,48,74,110,137,173,198,220,245,270,290],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100640969","motor-and-cognitive-telerehabilitation-in-a-virtual-environment-in-patients-with-post-stroke-sequelae-and-parkinsons-disease-100640969",false,"NCT07582497","Motor and Cognitive Telerehabilitation in a Virtual Environment in Patients With Post-stroke Sequelae and Parkinson's Disease","Telerehabilitation in a Virtual Environment for Sensorimotor and Cognitive Recovery in Patients With Post-stroke Sequelae and Parkinson's Disease: a Pilot Study","HOME VR REHAB","Inclusion Criteria:\n\n* Age \\>18 years old, both sex;\n* stroke or Parkinson diagnosis \\> or = 2 months;\n* upper limb impairment\n* informed consent signed\n\nExclusion Criteria:\n\n* ongoing clinical instability;\n* important cognitive impairment;\n* psychiatric, neurological, or internal medicine comorbidities;\n* severe rigidity or hypertonia;\n* severe visual deficit;\n* pregnancy women","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this interventional pilot trial is to evaluate whether a telerehabilitation protocol based on immersive virtual reality (VR) is effective and feasible for the recovery of cognitive and\u002For motor functions in patients with sequelae of ischemic or hemorrhagic stroke or with Parkinson's disease.\n\nThe main questions it aims to answer are:\n\n* Does the VR-based telerehabilitation protocol improve cognitive and\u002For motor outcomes compared to conventional rehabilitation?\n* Is the protocol feasible, defined as ≥80% adherence among participants? Is the system acceptable and user-friendly from the patient's perspective? Researchers will compare an interventional arm receiving telerehabilitation via an immersive VR home kit with a control arm receiving conventional rehabilitation according to standard clinical practice. Both groups will receive the same number of sessions, with the same duration and weekly frequency. Outcomes will be assessed at baseline (T0), after 4 weeks of treatment (T1), and at 3-month follow-up (T2).",[27,28,29],"Ictus","Stroke","Parkinson Disease",[31,32,33,34],"upper limb impairment","teleneurorehabilitation","virtual reality","telerehabilitation","NOT_YET_RECRUITING","2026-05-12",{"date":38,"type":39},"2026-05-14","ACTUAL",{"date":41,"type":21},"2026-06",{"date":43,"type":21},"2026-12",{"name":45,"class":46},"Azienda Usl di Bologna","OTHER_GOV",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":47},"100637251","the-impact-of-first-responder-intervention-on-survival-in-out-of-hospital-cardiac-arrest-in-emilia-romagna-region-100637251","NCT07589504","The Impact of First Responder Intervention on Survival in Out-of-Hospital Cardiac Arrest in Emilia-Romagna Region","FIRSST-RER Study: The Impact of First Responder Intervention on Survival in Out-of-Hospital Cardiac Arrest in Emilia-Romagna","FIRSST-RER","Inclusion Criteria:\n\n* Age ≥18 years\n* Confirmed out-of-hospital cardiac arrest (OHCA)\n* Emergency medical services activation with Advanced Life Support dispatch (Code Red Advanced Blue)\n* OHCA confirmed by return code 2-3-4 and\u002For NSIS codes (C0208 or C0205)\n* Event occurring between 1 January 2018 and 31 December 2025\n* Activation of the regional emergency medical system (Emilia-Romagna 118 system)\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Cardiac arrest not confirmed after EMS assessment\n* Cases with return code \\\u003C2 (misclassified as cardiac arrest)",{"count":57,"type":21},5200,"OBSERVATIONAL","Out-of-hospital cardiac arrest (OHCA) is a life-threatening emergency and one of the leading causes of death worldwide. Survival depends critically on how quickly help arrives and whether cardiopulmonary resuscitation (CPR) and defibrillation are started early. In recent years, many regions in Europe and Italy, including Emilia-Romagna, have introduced systems that alert nearby volunteers, called First Responders (FRs), through smartphone applications (such as DAE RespondER). These individuals can reach the patient before emergency medical services (EMS) and begin life-saving actions.\n\nThe FIRSST-RER study aims to evaluate whether the intervention of First Responders improves survival in patients with out-of-hospital cardiac arrest in Emilia-Romagna.\n\nThis is a multicentre observational study involving approximately 5,000 adult patients who experienced cardiac arrest between 2018 and 2025 and were treated by the regional emergency system.\n\nThe study compares two groups of patients:\n\nthose who received help from at least one First Responder activated via the app those who did not receive First Responder intervention\n\nThe main objective is to determine whether First Responders increase survival at 30 days after cardiac arrest.\n\nAdditional objectives include evaluating:\n\nsurvival at 6 months and 1 year neurological outcomes (brain function recovery)\n\nData for this study are collected from existing healthcare and emergency system databases, including EMS dispatch records, national health data systems, and the DAE RespondER platform.\n\nFor patients who survive, follow-up information may be collected through medical records or telephone contact.\n\nImportantly, this study does not involve any experimental treatments or changes in patient care. It is based entirely on data already collected during routine emergency care, and therefore does not pose additional risks to patients.\n\nAll data are handled securely and in compliance with privacy regulations. Personal identifiers are replaced with coded information (pseudonymisation), and only authorised researchers can access the data. Patients who are alive may be contacted to provide consent and additional follow-up information; participation is voluntary, and consent can be withdrawn at any time.\n\nThe results of this study will provide important evidence on the effectiveness of citizen responder systems and may help guide future improvements in emergency response organisation, public health strategies, and training programmes. Ultimately, the goal is to increase survival and improve outcomes for people experiencing cardiac arrest in the community.",[61],"Cardiac Arrest (CA)",[63,64,65],"first responder","out of hospital cardiac arrest","survival","2026-05-10",{"date":68,"type":39},"2026-05-15",{"date":70,"type":21},"2026-05",{"date":72,"type":21},"2026-12-31",{"name":45,"class":46},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},"100600377","vr-and-orthoses-for-rehabilitation-in-multiple-sclerosis-100600377","NCT07096700","VR and Orthoses for Rehabilitation in Multiple Sclerosis","Virtual Reality for Gait Training in Multiple Sclerosis (VIRTUE): an Interventional Feasibility Study","VIRTUE","Inclusion Criteria:\n\n* Confirmed diagnosis of multiple sclerosis\n* Age between 18 and 65 years\n* Both sexes\n* Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS \\> 100)\n* Expanded Disability Status Scale (EDSS between 3 and 6 inclusive)\n* Berg Balance Scale (BBS ≥ 46)\n* Indication for the use of the Exoband orthosis for gait assistance\n* Modified Fatigue Impact Scale (MFIS) physical subscale ≤ 20\n* Signed informed consent\n\nExclusion Criteria:\n\n* Presence of severe or current visual or auditory impairments\n* Relapses within the last 3 months\n* Presence of severe anxiety or depression\n* Severe spasticity patterns in the lower limbs or fixed distal tendon contractures\n* Presence of motion sickness symptoms induced by virtual reality (VR)","65 Years",{"count":84,"type":21},12,[24],"This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis (MS). The aim is to determine whether this approach can enhance clinical gait assessment and facilitate orthosis adaptation by replicating real-life scenarios within a safe and controlled environment. The virtual environment, accessed through a head-mounted display, will be delivered via a custom simulator incorporating standardized gait tasks embedded in everyday settings. This system is designed to minimize the artificial influence of clinical settings on walking performance, while providing clinicians with objective gait data for more comprehensive evaluation.",[88],"Multiple Sclerosis",[90,91,92,93,94,95,96,97,98,99],"Multiple sclerosis","Neurorehabilitation","Gait impairments","Virtual Reality","Wearable technology","Sensor-based monitoring","Inertial sensors","Physiological signals","Walking braces","Remote monitoring","RECRUITING","2026-03-27",{"date":103,"type":39},"2026-03-30",{"date":105,"type":39},"2026-03-02",{"date":107,"type":21},"2026-09",{"name":45,"class":46},2,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":122,"conditions":123,"keywords":4,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":109},"100546486","internet-based-interventions-for-cardiac-arrest-survivors-100546486","NCT06395558","intErnet-based iNterventions FOR Cardiac arrEst suRvivors","Internet-Based Interventions for Cardiac Arrest Survivors","ENFORCER","Inclusion Criteria:\n\n* Hospital discharge after out-of-hospital cardiac arrest with Cerebral Performance Category 1 or 2\n* Informed consent for participation in the study\n* Native Italian speaker or adequate understanding of the Italian language\n* Adequate ability to use the web to guarantee access to the contents\n\nExclusion Criteria:\n\n* Previous cognitive dysfunction\n* Previous psychiatric disease\n* Previous episode of out-of-hospital cardiac arrest","80 Years",{"count":120,"type":21},106,[24],"This randomized clinical trial will test whether an internet-based lifestyle intervention administered through a web app can foster Health Related Quality of Life in patients who survived an out-of-hospital cardiac arrest and suffer from these symptoms",[124,125,126,127,128,129],"Cognitive Impairment","Depression, Anxiety","Cardiac Arrest","Quality of Life","Social Functioning","Sexual Dysfunction","2026-03-25",{"date":103,"type":39},{"date":133,"type":39},"2024-08-05",{"date":135,"type":21},"2027-10-01",{"name":45,"class":46},{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":82,"enrollmentInfo":145,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":147,"conditions":148,"keywords":155,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":47},"100630810","renal-and-hepatic-abnormal-doppler-patterns-in-trauma-100630810","NCT07492511","Renal and Hepatic Abnormal Doppler Patterns in Trauma","Renal and hEpatiC abnoRmal dopplEr pAtterns iN Trauma: a Multicentre Prospective Observational Study","RECREANT","Inclusion Criteria:\n\n* Age 18-65 years;\n* Admission within 24h from traumatic injury;\n* ISS \\>15\n\nExclusion Criteria:\n\n1. Age \\\u003C18 or \\>65;\n2. Known heart failure (NYHA ≥II);\n3. Chronic kidney disease (any stage) or chronic RRT;\n4. Chronic respiratory disease needing home O₂ or ventilation;\n5. Radiological evidence of vascular or parenchymal renal injury on trauma CT precluding reliable Doppler assessment",{"count":146,"type":21},350,"The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma.\n\nThe main questions it aims to answer are:\n\n* How reliably can trained operators measure renal Doppler and venous congestion scores (RDRI and VExUS) across different hospitals?\n* How common are abnormal kidney and liver blood flow patterns in major trauma patients during the first 72 hours of ICU admission?\n* Are these abnormal patterns associated with acute kidney injury or the need for mechanical ventilation?\n\nParticipants admitted to ICUs or high-dependency units (HDUs) with major trauma (Injury Severity Score \\>15) will undergo non-invasive bedside ultrasound assessments at admission and at 24, 48, and 72 hours. No additional treatments or interventions will be given as part of this study. Kidney function will also be checked at 6 months after hospital discharge.",[149,150,151,152,153,154],"Trauma (Including Fractures)","Trauma Patients","Kidney Disease","Hypovolemia","Hypervolemia","Kidney Failure",[156,157,158,159,160,161,162,163,164,165],"VEXUS","trauma","kidney injury","kidney failure","Venous congestion","renal perfusion","Renal Doppler resistive index","major trauma","Hemodynamic phenotyping","ICU","2026-03-19",{"date":130,"type":39},{"date":169,"type":39},"2026-03-01",{"date":171,"type":21},"2030-06-30",{"name":45,"class":46},{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":183,"conditions":184,"keywords":186,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":47},"100619775","neurogenetic-and-hemodynamic-of-migraine-aura-and-pfo-100619775","NCT07349004","Neurogenetic And Hemodynamic Of Migraine Aura And Pfo","Association Between PFO and Migraine With Aura: A Case-Control Observational Study With Genetic and Neurosonological Analysis","PFOCUS","Inclusion Criteria:\n\n* Diagnosis of migraine with aura (according to Chapter 1.2 of the International Classification of Headache Disorders, 3rd edition \\[ICHD-3\\])\n* Age ≥ 18 years\n* Both sexes\n* Obtained written informed consent to participate in the study\n\nExclusion Criteria:\n\n* History of congenital heart disease",{"count":182,"type":21},240,"The PFOCUS Study aims to clarify the relationship between patent foramen ovale (PFO) and migraine with aura (MA). Patients diagnosed with MA according to ICHD-3 criteria will be classified as cases (PFO+) or controls (PFO-) based on the presence or absence of a right-to-left shunt detected by transcranial Doppler or a previously documented PFO. The study will enroll 240 adult participants over 36 months.\n\nThe primary objective is to determine whether genetic variants differ significantly between patients with MA with and without PFO. Secondary objectives include assessing cerebral blood flow regulation and platelet function in patients with MA with and without PFO.\n\nParticipants will undergo a single study visit including the collection of demographic and clinical data and a comprehensive neurosonological assessment. This will include microembolic signal counts, cerebrovascular reactivity testing, and a contrast-enhanced transcranial Doppler study for shunt detection. Blood samples will be collected for whole-exome sequencing (with a focus on NOTCH3 and an expanded gene panel) and for platelet aggregometry.\n\nThe study is expected to provide new insights into the biological mechanisms linking PFO and MA-potentially involving endothelial dysfunction, altered vascular smooth muscle responses, or platelet activation-thereby informing prevention strategies and guiding future research.",[185],"Migraine With Aura",[187,188,189],"patent foramen ovale","migraine with aura","CADASIL","2026-02-09",{"date":192,"type":39},"2026-02-11",{"date":194,"type":39},"2025-11-24",{"date":196,"type":21},"2028-11",{"name":45,"class":46},{"id":199,"slug":200,"hasResults":11,"nctId":201,"briefTitle":202,"officialTitle":203,"acronym":204,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":17,"minAge":206,"maxAge":207,"enrollmentInfo":208,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":210,"conditions":211,"keywords":4,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":213,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":219},"100540803","autoimmune-dementia-predictors-of-neuronal-synaptic-antibodies-in-patients-with-new-onset-cognitive-impairment-100540803","NCT06321588","Autoimmune Dementia: Predictors of Neuronal Synaptic Antibodies in Patients With New-ONset Cognitive Impairment","Autoimmune Dementia: Predictors of Neuronal Synaptic Antibodies in Patients With New-ONset Cognitive Impairment and Their Relevance in Non-encephalitic formS: The ADONIS Study","ADONIS","Inclusion Criteria:\n\n* both sexes\n* adult (aged between 40 and 90 years)\n* patients with a diagnosis of new-onset neurocognitive disorders (major and minor), as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, with onset within the previous 24 months\n\nExclusion Criteria:\n\n\\- presence of a history of seizures within 4 weeks from onset.","40 Years","90 Years",{"count":209,"type":21},300,"The goal of this observational study is to investigate the frequency and the possible pathogenic role of neuronal synaptic antibodies (NSAb) in patients with cognitive impairment (CI). The main questions it aims to answer are:\n\n1. the frequency and associated features of NSAb in patients with CI and the usefulness of a clinical score in improving autoimmune dementia (AID) diagnosis;\n2. the clinical significance of NSAb in patients with CI not fulfilling the autoimmune encephalitis (AE) criteria and serum NSAb (NSAb-pos-CI);\n3. the impact of blood-brain-barrier (BBB) dysfunction on their pathogenicity.",[124,212],"Dementia",{"date":192,"type":39},{"date":215,"type":39},"2023-05-10",{"date":217,"type":21},"2026-06-30",{"name":45,"class":46},3,{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":228,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":234,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":242,"leadSponsor":244,"locationsCount":47},"100600376","targeted-temperature-management-in-acute-ischemic-stroke-100600376","NCT07096687","Targeted Temperature Management in Acute Ischemic Stroke","Targeted Temperature Management for Neuroprotection in Acute Ischemic Stroke: A Randomized Controlled Pilot Trial","TTM-STROKE","Inclusion Criteria:\n\n* Age \\>18 years;\n* Both sexes;\n* Diagnosis of acute ischemic stroke confirmed by clinical evaluation by a neurologist and neuroimaging (CT or brain MRI);\n* Acute ischemic stroke with symptom onset within 48 hours;\n* Anterior circulation stroke with evidence on neuroimaging (CT angiography) of occlusion of the middle cerebral artery in segments M1, M2, or M3;\n* NIHSS score between 6 and 25;\n* First clinical stroke;\n* Axillary temperature ≥36°C and \\\u003C37°C;\n* Informed consent obtained for study participation.\n\nExclusion Criteria:\n\n* Stroke involving multiple vascular territories;\n* Presence of intracerebral hemorrhage;\n* Pregnancy;\n* Moderate-to-severe or severe pre-stroke disability defined as mRS \\>3;\n* Presence of a cardiac pacemaker or any other conditions contraindicating brain MRI.",{"count":229,"type":21},22,[24],"The goal of this interventional trial is to evaluate whether the CB240\\_Aurora medical device is effective for targeted temperature management in adult patients with acute ischemic stroke. The main questions it aims to answer are: Is the CB240\\_Aurora effective in maintaining normothermia in patients with acute ischemic stroke? Does the medical device improve clinical and radiological outcomes? Is the medical device well tolerated by patients? Researchers will compare an interventional arm, in which the CB240\\_Aurora measures and treats body temperature to maintain normothermia, with a control arm, in which the CB240\\_Aurora only measures but does not treat body temperature. Participants will wear the medical device for 72 consecutive hours in the Stroke Unit. Outcome assessments will be performed at 72 hours, 7 days, and 3 months.",[233],"Ischemic Stroke",[235,236,237],"ischemic stroke","neuroprotection","targeted temperature management","2025-09-11",{"date":240,"type":39},"2025-09-17",{"date":238,"type":39},{"date":243,"type":21},"2027-03-31",{"name":45,"class":46},{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":251,"eligibilityCriteria":252,"healthyVolunteers":253,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":254,"targetDuration":4,"studyType":22,"phases":256,"briefSummary":257,"conditions":258,"keywords":260,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":47},"100573158","the-use-of-brief-motivational-interviewing-in-community-health-centers-100573158","NCT06742645","The Use of Brief Motivational Interviewing in Community Health Centers.","The Use of Brief Motivational Interviewing in Community Health Centers. Controlled Trial on Quality of Life and Perceived Health Status","BMICHC","Inclusion Criteria:\n\n* first visit to the Cardiology or Endocrinology\u002FDiabetology or Rheumatology or Basic Dietetics services or other medical specialties of the Borgo-Reno or Navile Community Home or referred to them.\n* resident in the AUSL of Bologna\n* age ≥18 years\n\nExclusion Criteria:\n\n* second or more visits to the Cardiology or Endocrinology\u002FDiabetology or Rheumatology or Basic Dietetics services, or other medical specialties of the Borgo-Reno or Navile Community House or referred to them.\n* first visit to a service not indicated in the inclusion criteria\n* not resident in the territory of the AUSL of Bologna\n* age \\\u003C18 years",true,{"count":255,"type":21},304,[24],"The research project aims to detect the effect of the Brief Motivational Interview (BMI) on the motivation to change risky behaviors and the adoption of healthy lifestyles by citizens attending Community Health Centers (CdC). The controlled, multicenter, prospective design study involves the enrollment of 304 people, with 152 at the Borgo Reno CdC and 152 at the Navile CdC.",[259],"Healthy Subjects",[261],"Motivational Interviewing","2024-12-18",{"date":264,"type":39},"2024-12-19",{"date":266,"type":39},"2024-12-09",{"date":268,"type":21},"2026-02-28",{"name":45,"class":46},{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":276,"eligibilityCriteria":277,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":278,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":279,"conditions":280,"keywords":4,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":47},"100558558","risk-factors-for-neck-phlegmon-after-percutaneous-tracheostomy-in-icu-100558558","NCT06552676","riSk Factors fOR neCk phlEgmon afteR pErcutaneous tRacheostomy in ICU","Risk Factors for Neck Phlegmon After Percutaneous Tracheostomy in ICU","SORCERER","Inclusion Criteria:\n\n* Age greater than 18 years\n* Presence of indication for tracheostomy\n\nExclusion Criteria:\n\n* Failure of the percutaneous tracheostomy technique or recourse to surgical tracheostomy",{"count":209,"type":21},"Primary Purpose: To investigate the incidence and risk factors related to the appearance of tracheal phlegmon in patients undergoing percutaneous tracheostomy.\n\nParticipant Population\u002FPrimary Condition: Patients admitted to Intensive Care\n\nMain Questions Aims to Answer:\n\n1. \\- What are the risk factors associated with the development of tracheal phlegmon percutaneous tracheostomy?\n2. \\- How does the appearance of tracheal phlegmon impact intensive care stay, hospital stay, mortality, and Health-related quality of life?\n\nParticipants will be followed up after undergoing tracheostomy for 7 days to identify eventual phlegmons.\n\nAt the two-year follow-up, the health-related quality of life will be assessed",[281,127],"Tracheostomy Complication","2024-08-10",{"date":284,"type":39},"2024-08-14",{"date":286,"type":39},"2018-08-09",{"date":288,"type":21},"2025-01-31",{"name":45,"class":46},{"id":291,"slug":292,"hasResults":11,"nctId":293,"briefTitle":294,"officialTitle":294,"acronym":295,"eligibilityCriteria":296,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":297,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":299,"conditions":300,"keywords":305,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":307,"startDateStruct":309,"completionDateStruct":311,"leadSponsor":313,"locationsCount":314},"100420916","prehospital-management-of-hypotensive-trauma-in-hems-100420916","NCT04760977","Prehospital Management of Hypotensive Trauma in HEMS","SPITFIRE","Inclusion Criteria:\n\n* Age \\> 18 years\n* Witnessed traumatic event managed by HEMS\n* Shock at first evaluation (Systolic blood pressure \\\u003C 90 mmHg)\n* Suspect or obvious ongoing haemorrage\n\nExclusion Criteria:\n\n* Patients in cardiac arrest at HEMS arrival in which resuscitation is not started or interrupted by HEMS crew",{"count":298,"type":21},500,"Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality.\n\nAlso new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes.\n\nMoreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies.\n\nWith this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome",[301,302,303,304],"Hypotension and Shock","Wounds and Injuries","Emergencies","Critical Care",[306,302,303,304],"Transportation of Patients",{"date":308,"type":39},"2024-08-13",{"date":310,"type":39},"2021-05-01",{"date":312,"type":21},"2026-05-01",{"name":45,"class":46},16,""]