[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Balgrist University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":260},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,46,69,92,122,143,173,193,211,237],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100632421","3t-magnetic-resonance-neurography-100632421",false,"NCT07513467","3T Magnetic Resonance Neurography","High-resolution MR Neurography Evaluation of the Cervical Spine at 3 Tesla","3T MRN","Inclusion Criteria:\n\n\\- written consent to agree to participate in this study\n\nExclusion Criteria:\n\n* \\\u003C18 years of age\n* pregnancy\n* known cervical spine pathology or history of neck surgery\n* contraindication to perform non-contrast-enhanced MRI",true,"ALL","18 Years",{"count":21,"type":22},30,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate whether optimized high-resolution MRI can better visualize very fine nerves in the cervical spine and neck region compared to standard MRI. The main question it aims to answer is:\n\nCan high-resolution MRI reliably show small nerves and potentially detect their injuries or diseases that are often invisible on conventional MRI scans?\n\nParticipants will come once to Balgrist University Hospital for a one-hour visit. They will fill out a questionnaire and have a single 30-minute MRI scan of the cervical spine without contrast.",[26],"Healthy Adults",[28,29,30,31,32],"Cervical spine","MRI","3 Tesla","Magnetic Resonance Neurograghy","Cervical nerves","NOT_YET_RECRUITING","2026-03-30",{"date":36,"type":37},"2026-04-07","ACTUAL",{"date":39,"type":22},"2026-06",{"date":41,"type":22},"2028-06",{"name":43,"class":44},"Balgrist University Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100396705","7-tesla-mri-evaluation-of-the-spine-asymptomatic-100396705","NCT04445584","7 Tesla MRI Evaluation of the Spine (Asymptomatic)","7 Tesla MRI Evaluation of the Spine","Inclusion criteria:\n\n* Informed consent as documented by signature (Appendix Informed Consent Form)\n* \\>18 years old\n* Patients presenting chronic back pain (\\> 2 months) without recent trauma, previous MRI (1,5 or 3T) for clinicals indications or asymptomatic individuals (for depicting normal microanatomy)\n\nExclusion criteria:\n\n* previous surgery\n* tumor patients\n* pregnancy or breast feeding\n* any MRI contra-indications\n* any MRI contra-indications",{"count":54,"type":22},600,"High-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots\u002Fganglia. Secondly, detailed anatomy of vertebral artery and its relation to neural structures \u002F foramina can be assessed.",[57,58,59],"Magnetic Resonance Imaging","Cervical Spine Anatomy","Reference Standard","RECRUITING","2025-10-01",{"date":63,"type":37},"2025-10-02",{"date":65,"type":37},"2020-06-01",{"date":67,"type":22},"2027-09-30",{"name":43,"class":44},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":45},"100366210","short-post-surgical-antibiotic-therapy-in-spine-infections---a-prospective-randomized-unblinded-non-inferiority-trial-100366210","NCT04048304","Short Post-surgical Antibiotic Therapy in Spine Infections - a Prospective, Randomized, Unblinded, Non-inferiority Trial","Short Post-surgical Antibiotic Therapy in Spine Infections - a Pro-spective, Randomized, Unblinded, Non-inferiority Trial","Inclusion Criteria:\n\n* Spine surgery and intraoperative debridement with any technique\n* At least 12 months of scheduled follow-up from hospitalization\n* Bacterial spine infection of any nature, independently of implants or co-morbidities\n\nExclusion Criteria:\n\n* Mycobacterial, fungal, nocardial, and Actinomyces infections in the spine\n* Non-resected cancer in the infection site\n* Bone marrow or recent solid organ transplant patient (Recent: \\\u003C5 years)\n* Any other infection in the patient requiring more than 6 weeks of antibiotic therapy\n* More than three intraoperative debridements performed for spine infection\n* Absence of at least one surgical intraoperative debridement of infection",{"count":77,"type":22},236,"INTERVENTIONAL",[80],"NA","We implement a prospective, randomized, unblinded, non-inferiority trial regarding the duration of systemic, targeted antibiotic therapy after the first surgical debridement for spine infection; randomizing 1:1 between\n\n1. Six and twelve weeks of antibiotic therapy if there is an implant left in place\n2. Three and six weeks of antibiotic therapy if there is no implant left",[83],"Infection","2025-02-20",{"date":86,"type":37},"2025-02-21",{"date":88,"type":37},"2019-07-31",{"date":90,"type":22},"2025-12-31",{"name":43,"class":44},{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":78,"phases":102,"briefSummary":103,"conditions":104,"keywords":108,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":45},"100517995","vertebropexy---randomized-controlled-trial-100517995","NCT06024785","Vertebropexy - Randomized-controlled Trial","Comparison of Ligamentous Fixation Technique (Vertebropexy) Versus Conventional Decompression or Fusion Surgery for Degenerative Lumbar Spinal Disease: A Randomized Controlled Trial","VPRCT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Single-level or two-level lumbar surgery needed\n* Indication for decompression surgery in patients with spinal canal stenosis and additional stable degenerative listhesis (without facet joint effusion ≥ 2mm)\n* Indication for fusion surgery in patients with spinal canal stenosis and additional unstable degenerative listhesis (facet joint effusion ≥ 2mm), in patients with foraminal stenosis and additional degenerative listhesis, and in patients with segment degeneration of the disc\n* Understanding in German language\n\nExclusion criteria:\n\n* Indication for decompression and\u002For fusion surgery in patients with solely disc herniation, fractures, lytic listhesis, tumor\n* Patients undergoing revision surgery for infection\n* Patients undergoing revision surgery on the same level if bony structures have been removed (e.g. prior laminectomy or midline decompression)\n* Patients undergoing revision surgery in case of prior fusion surgery\n* Inability to understand the study for linguistic or cognitive reasons\n* Anticipated clinical follow-up of less than 6 weeks after inclusion\n* Participation in other clinical trials",{"count":101,"type":22},164,[80],"To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)",[105,106,107],"Degeneration","Spinal Stenosis","Fusion of Spine",[109,110,111,112,113],"degenerative lumbar spinal disease","decompression","fusion","vertebropexy","ligamentous fixation","2025-02-11",{"date":116,"type":37},"2025-02-13",{"date":118,"type":37},"2025-01-16",{"date":120,"type":22},"2028-12",{"name":43,"class":44},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":17,"sex":128,"minAge":19,"maxAge":129,"enrollmentInfo":130,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":4},"100578635","monitored-effects-of-physical-activity-on-fetal-heart-rate-by-using-a-wireless-non-invasive-device-100578635","NCT06813859","Monitored Effects of Physical Activity on Fetal Heart Rate by Using a Wireless Non-invasive Device","Inclusion Criteria:\n\n* Presence of signed informed consent form\n* healthy pregnant active female over the age of 18 years and below 45 years\n* sporting activity \\>4h\u002Fweek on 2 or more weekdays\n* single pregnancy, between 28+0 and 34+0 weeks of pregnancy\n\nExclusion Criteria:\n\n* No signed informed consent form or revocation of consent\n* pre-existing pregnancy complications","FEMALE","45 Years",{"count":131,"type":22},20,"Effect of acute exercise testing in pregnant athletes on maternal and fetal heart rate, fetal\u002Fmaternal bloodflow and cardiotocogramm assessment.",[134],"Fetal Distress","2025-02-04",{"date":137,"type":37},"2025-02-07",{"date":139,"type":22},"2025-02-01",{"date":141,"type":22},"2027-02-27",{"name":43,"class":44},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":78,"phases":153,"briefSummary":155,"conditions":156,"keywords":160,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":45},"100477854","phase-3-broad-spectrum-antibiotic-prophylaxis-in-tumor-and-infected-orthopedic-surgery-100477854","NCT05502380","Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery","Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Sur-gery - the Prospective-randomized, Microbiologist-blinded, Stratified, Superiority Trials - BAPTIST Trials","BAPTIST","Inclusion Criteria\n\n* Age ≥ 18 years\n* Surgery under current or recent therapeutic antibiotics (antibiotic-free window \\\u003C14 days and past antibiotic prescription \\>4 days)\n* Surgery for open fractures and wounds; including 2nd and 3rd looks\n* Potentially contaminated wound revision in the operating theatre\n* Tumor (oncologic) surgery (if prior radiotherapy and\u002For bone involvement)\n* Spine surgery with ASA-Score \\>= 3 points, sacral involvement, or re-vision surgery\n* Known skin colonization with multidrug-resistant Gram-negative bacteria\n\nExclusion Criteria:\n\n* Inability to understand the study procedure for linguistic or cognitive rea-sons\n* Surgery without intraoperative microbiological samples\n* Allergy or major intolerance to vancomycin and\u002For gentamicin\n* Anticipated clinical follow-up of less than 6 weeks after inclusion\n* Pregnant or breastfeeding women\n* Known carriage of multiresistant Gram-negative bacteria in the urine or anal region",{"count":152,"type":22},1100,[154],"PHASE3","The perioperative antibiotic prophylaxis is evidence-based in orthopedic surgery. While its duration ranges from a single dose to three doses throughout the world, the choice of the prophylactic agents is undisputed. Worldwide, the surgeons use 1st or 2nd-generation cephalosporins (or vancomycin in some cases).\n\nHowever, there are particular clinical situation with a high risk of antibiotic-resistant surgical site infections (SSI); independently of the duration of adminis-tered prophylaxis. These resistant SSI's occur in contaminated wounds, or during surgery under current therapeutic antibiotics, and base on \"selection\" by antibiotics used for therapy or for prophylaxis.",[157,158,159],"Surgical Site Infection","Microbial Colonization","Antibiotic Resistant Infection",[161,162,163,164],"Perioperative antibiotic prophylaxis","Selection","High Risk patients","Ranndomized-Controlled Trial","2024-11-28",{"date":167,"type":37},"2024-12-02",{"date":169,"type":37},"2022-09-15",{"date":171,"type":22},"2025-12-12",{"name":43,"class":44},{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":4,"eligibilityCriteria":179,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":180,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":182,"conditions":183,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":45},"100396396","high-resolution-7-tesla-mri-of-c-spine---comparison-with-3-tesla-mri-100396396","NCT04441554","High-resolution 7 Tesla MRI of C-spine - Comparison with 3 Tesla MRI","High-resolution MRI (7 Tesla) of Foraminal Stenosis and Differentiation of the Degenerated Discovertebral Unit - Comparison with 3 Tesla MRI","Inclusion Criteria:\n\n* Informed consent as documented by signature (Appendix Informed Consent Form)\n* \\>18 years old\n* Patients with cervical back pain (radiculopathy) and scheduled surgery for foraminal stenosis or central stenosis or cervical periradicular injection therapy (PRT)\n\nExclusion Criteria:\n\n* previous surgery\n* tumor patients\n* pregnancy or breast feeding\n* any MRI contra-indications",{"count":181,"type":22},100,"High-resolution MRI (7 Tesla) of the cervical spine is capable to differentiate osseous spurs from discus-material and better depict the compressed nerve in the neuroforamen compared to 3T MRI.\n\nProvide the surgeon with a detailed high-resolution anatomical image before surgery and potential no need for CT (if the bony anatomy is of crucial importance).",[57,184],"Cervical Spine Disease","2024-09-02",{"date":187,"type":37},"2024-09-05",{"date":189,"type":37},"2020-07-31",{"date":191,"type":22},"2025-12-30",{"name":43,"class":44},{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":200,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":205,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":45},"100396429","footankle-at-7t-mri-100396429","NCT04441983","Foot\u002FAnkle At 7T MRI","High-Resolution MRI (7 Tesla) Findings of the Plantar Plate Compared with Current Clinical Standard Sequences (1.5 or 3 Tesla) and Surgical Reference Standard","Inclusion Criteria:\n\n* Informed consent as documented by signature (Appendix Informed Consent Form)\n* at least 18 years old\n* Study group: Patients with specific pathologies (i.e. Morton neuroma, tendon tears, plantar plate tears) as proven by 1,5 or 3T MRI or asymptomatic subjects (to look at the normal microanatomy of different structures, mainly the plantar plate)\n* Control group: No evidence of the respective pathology.\n\nExclusion Criteria:\n\n* previous foot surgery with metal in vivo\n* pregnancy or breast feeding\n* any MRI contra-indications",{"count":201,"type":22},80,"* To evaluate standard clinical sequences for 7 Tesla MRI of the foot and\u002For ankle to improve detailed depiction of the complex anatomy of this region.\n* To evaluate various pathologies of the foot and\u002For ankle (plantar plate tears, Morton neuroma, tendon tears, ligament tears etc.).",[204],"Plantar Plate Tear",{"date":187,"type":37},{"date":207,"type":37},"2022-02-01",{"date":209,"type":22},"2025-10-31",{"name":43,"class":44},{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":218,"enrollmentInfo":219,"targetDuration":4,"studyType":78,"phases":221,"briefSummary":222,"conditions":223,"keywords":226,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":236,"locationsCount":4},"100558521","augmented-reality-in-learning-anatomy-the-teachanatomy-randomized-cross-over-trial-100558521","NCT06552195","Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial","Hologram-Based Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial","Inclusion Criteria:\n\n* Medical students attending the 1st or 2nd year of undergraduate medical education\n* Must not have prior anatomical education\n\nExclusion Criteria:\n\n* Epilepsy\n* Binocular vision disorder such as strabismus\n* Current head and\u002For neck injuries\n* Inflammation of the scalp and\u002For eye\n* Amputations or partial amputations of the hands","25 Years",{"count":220,"type":22},300,[80],"Cadaver use in anatomy education is undergoing several limitations in many universities, due to high costs, time constraints and supply difficulties. As alternatives to cadaver dissections, new teaching methods based on visual technologies, such as augmented reality (AR), are being implemented worldwide.\n\nAugmented reality (AR), based on virtual interactive 3-dimensional elements (holograms) overlaid in the real-world, represents a promising alternative to explore the human body. In this study, we will test the efficacy of AR as an alternative teaching method in anatomy education by comparing traditional learning methods based on 2-dimensional (2D) images, videos, and online learning programs with the novel AR learning module The primary endpoint will consist of the score in the final theoretical and practical knowledge tests, assessed at two timepoints: immediately after the study session and after 3 months.\n\nSecondary endpoints will include adverse health symptoms and user experience, assessed immediately after the study session.",[224,225],"Augmented Reality","Anatomy Education",[227,228,229],"Anatomy teaching","Augmented reality","Magic leap","2024-08-09",{"date":232,"type":37},"2024-08-13",{"date":234,"type":22},"2024-10-01",{"date":90,"type":22},{"name":43,"class":44},{"id":238,"slug":239,"hasResults":11,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":244,"enrollmentInfo":245,"targetDuration":4,"studyType":78,"phases":247,"briefSummary":248,"conditions":249,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":45},"100448486","phase-3-perioperative-dexamethasone-reduces-postoperative-pain-and-nausea-after-periacetabular-osteotomy-100448486","NCT05120076","Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy","Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy- a Double-blinded Placebo Controlled RCT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* General anasthesia\n* Elective periacetabular osteotomy for any reason\n* Written informed consent as documented by signature (Appendix Informed Consent Form)\n* Competent German language skills\n\nExclusion Criteria:\n\n* Chronic pain patient, chronic lower back pain\n* Steroid or immunosuppressive drugs used within 6 months of surgery\n* Renal failure, hepatic failure\n* Relevant allergies\n* Pregnancy\u002F Breast feeding\n* Contraindications for Fortecortin treatment according to Swissmedic\n* Previous enrollment into the current study\n* Participation in another study with investigational drug within the 30 days preceding and during the present study\n* Known or suspected non-compliance, drug or alcohol abuse Illness according to \"Warnings and Precautions of Dexamethasone and NaCl\"","99 Years",{"count":246,"type":22},60,[154],"The purpose of this study is to assess the effect of Dexamethasone on postoperative pain and nausea after periacetabular osteotomy.",[250,251,252],"Pain","Postoperative Nausea","Amount of Postoperative Opioid Use in Milligrams",{"date":254,"type":37},"2024-08-12",{"date":256,"type":37},"2021-07-16",{"date":258,"type":22},"2024-08-31",{"name":43,"class":44},""]