[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Basque Health Service\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100642714","scaling-up-the-integrated-care-pathway-for-acute-asthma-to-all-osakidetza-pediatric-services-through-a-cluster-randomized-smart-design-100642714",false,"NCT07642388","Scaling up the Integrated Care Pathway for Acute Asthma to All Osakidetza Pediatric Services Through a Cluster-randomized SMART Design","Scaling up the Integrated Care Pathway for Acute Asthma to All Osakidetza Pediatric Services Through a Cluster-randomized Sequential, Multiple Assignment, Randomized Trial (SMART) Design","Eligibility for healthcare settings:\n\n\\- All Pediatric Services (Primary Care n=108 and Hospital Care n=9) from 11 of the 13 Osakidetza Integrated Healthcare Organizations that are not currently implementing the ASMAbat Pathway.\n\nEligibility for professionals:\n\n* Primary Care pediatricians and nurses\n* Pediatricians and nurses in the Pediatric Emergency Department\n* Pediatricians and nurses on the inpatient ward\n* Pediatric Intensive Care pediatricians and nurses\n* Pediatric Pneumology pediatricians and nurses\n\nEligibility for patients:\n\nPatients between 2 and 14 years that have being attended between the 1st of July 2026 and the 28th of February 2029, and with an acute episode of asthma, defined as:\n\n* an episode of wheezing and a previous diagnosis of asthma or with a previous episode of wheezing\n* a first episode in a child older than 2 years with a personal\u002Ffamily history of atopy and\u002For with an objective response to bronchodilators as assessed by a severity Score","ALL","2 Years","14 Years",{"count":20,"type":21},4680,"ESTIMATED","INTERVENTIONAL",[24],"NA","The main goal of this study is to evaluate the effectiveness of adaptive sequential implementation strategies based on facilitation in promoting the sustainable and widespread adoption and scaling up of the Integrated Care Pathway for Acute Asthma - ASMAbat across all Primary Care and Hospital Pediatric Services of Osakidetza - Basque Health Service.",[27],"Asthma in Children","NOT_YET_RECRUITING","2026-06-15",{"date":31,"type":32},"2026-06-16","ACTUAL",{"date":34,"type":21},"2026-07-01",{"date":36,"type":21},"2029-02-28",{"name":38,"class":39},"Basque Health Service","OTHER_GOV",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":40},"100618817","reduction-of-low-value-prescribing-through-audit-and-feedback-100618817","NCT07336550","Reduction of Low-value Prescribing Through Audit and Feedback","AFFAP Trial: The Comparative Evaluation of Audit and Feedback-based De-implementation Strategies to Reduce Low-value Prescribing in Primary Care in Patients Over 65 Years of Age.","AFFAP","PRIMARY CARE CENTERS IN THE BARAKALDO-SESTAO INTEGRATED HEALTHCARE ORGANISATION OF OSAKIDETZA-BASQUE HEALTH SERVICE:\n\nInclusion Criteria:\n\n* collaboration is achieved from at least 51% of the General Practitioners (GP) or at least 4 GPs\n* At least 60 patients aged 65 years or older on at least one of the drugs of interest that may be potentially inappropriately prescribed\n\nExclusion Criteria:\n\n* N\u002FA\n\nPATIENTS ASSIGNED TO THE PARTICIPATING PC CENTERS:\n\nInclusion Criteria:\n\n* Patients over 65 years of age with any of the following unsuitability criteria:\n* PIP of benzodiazepines: patients on benzodiazepines for more than 3 months\n* PIP of proton pump inhibitors: patients on proton pump inhibitors for more than 8 weeks without a diagnosed gastrointestinal disease and with no long-term prescription of gastrotoxic drugs.\n* PIP of opioids: patients on opioids for non-cancer pain for more than 3 months.\n\nExclusion Criteria:\n\n* Patients who, in the opinion of the general practitioner, are not suitable candidates for tapering or discontinuation of the potentially inappropriately prescribed drug\n* Patients residing in care homes\n* Patients receiving palliative care",true,"65 Years",{"count":52,"type":21},540,[24],"The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on processes and outcomes, for reducing the rate of patients over 65 years of age with potentially inappropriate prescribing (PIP) of benzodiazepines, proton pump inhibitors and opioids.\n\nA closed-cohort stepped-wedge cluster-randomised trial will be conducted in nine PC centres from Barakaldo-Sestao Integrated Health Organization, Basque Health Service (Osakidetza). All health centre clusters will start under the control condition, and after an initial study period of 4 months in the control phase, one centre per step at 1-month intervals will be randomly assigned to crossover to the intervention, under which they will be exposed to an additional component of AF, namely, primary care pharmacist-led facilitation.\n\nMixed-methods analysis will be performed, gathering quantitative data to assess the results of the implementations at health centre and clinician levels, and qualitative data to assess the feasibility and perceived impact of the de-implementation strategies from the clinicians' perspective, and explore the experience and satisfaction of patients regarding the healthcare received.\n\nThis study will provide useful knowledge on the effect attributable to a more intensive AF strategy (facilitated AF) compared to standard procedures of AF reports, and of the characteristics of AF that are most effective.",[56,57,58],"Inappropriate Prescribing","Implementation Science","Behavioral Sciences",[60,61,62,63,64,65,66],"low-value pharmacological prescription","De-implementation","Stepped-wedge design","Benzodiazepines","Proton pump inhibitors","Opioids","audit and feedback","2026-05-11",{"date":69,"type":32},"2026-05-13",{"date":71,"type":21},"2026-06",{"date":73,"type":21},"2027-12",{"name":38,"class":39},{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":40},"100549700","asthma-crisis-in-paediatrics-impact-of-a-care-pathway-in-primary-and-hospital-care-100549700","NCT06437444","Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care","Eligibility for professionals:\n\n* Primary Care paediatricians and nurses\n* Paediatricians and nurses in the Paediatric Emergency Department\n* Paediatricians and nurses on the inpatient ward\n* Paediatric Intensive Care paediatricians and nurses\n* Paediatric Pneumology paediatricians and nurses\n\nEligibility for patients:\n\nPatients between 2 and 14 years,that have being attended between the 7 May 2023 and the 7 May 2025, and with an acute episode of asthma, defined as:\n\n* an episode of wheezing and a previous diagnosis of asthma or with a previous episode of wheezing\n* a first episode in a child older than 2 years with a personal\u002Ffamily history of atopy and\u002For with an objective response to bronchodilators as assessed by the Pulmonary Score",{"count":82,"type":21},249,[24],"This study aims to evaluate the effect of the implementation of the new Asthma Integrated Care Pathway in the Basque Healthcare Service for the improvement of care for children with asthma attacks and the reduction of variability between professionals and care settings in this care practice. Asthma is the most common chronic disease in children and has a major impact on people's quality of life. The Asthma Integrated Care Pathway is a structured multidisciplinary care plan that details the essential steps in the care of patients with mild-moderate asthma attacks and the coordinated practice of the agents involved as dictated by the evidence. This pathway will include quality indicators of compliance with diagnostic criteria, assessment of severity and prescription of drugs, as well as the experience of families and professionals, which have been collected in meetings designed for this purpose.\n\nThe study consists in a mixed methods implementation trial with two phases:\n\n1. Phase I: a quantitative evaluation will be carried out to assess implementation outcomes at the professional level through a pretest-posttest quasi-experimental study with paired control group, with a ratio of 1:2. The primary outcome variable will be the overall percentage of bronchodilator treatment with a spacer chamber in children diagnosed with mild-moderate asthma attacks. We will also include as outcomes to be measured the registration rate of the Pulmonary Score, the recording rate of the assessment of persistent asthma symptoms, and the rate of initiation of background treatment in children with persistent asthma symptoms. These variables will be analysed using differences in pre- and post-intervention outcome measures between the intervention and control groups.\n2. Phase II: a qualitative evaluation will be carried out through a structured process with discussion groups focused on the identification of the main barriers and facilitators for the provision of recommended clinical practice related to asthmatic crisis in mild-moderate cases established by the Asthma Integrated Care Pathway. A purposive sample of paediatricians stratified by level of care and service organisations will be recruited to ensure that all views are represented in the discussion groups. The structured script will be designed with questions to explore each of the domains of the Theoretical Domains Framework (TDF).\n\nThe study will be carried out mainly in two integrated healthcare organizations (IHO), which are made up of two primary care areas and the paediatric reference hospital emergency department of both areas, as well as the hospitalisation, intensive care and paediatric pneumology departments of said hospital, to extend in the future the Asthma Integrated Care Pathway to the rest of the Basque Health Service IHOs.",[27,57],"RECRUITING","2025-09-16",{"date":89,"type":32},"2025-09-19",{"date":91,"type":32},"2023-05-07",{"date":93,"type":21},"2026-05-07",{"name":38,"class":39},""]