[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Beijing Institute of Heart, Lung and Blood Vessel Diseases\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":85},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,62],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100303662","diagnosis-and-prognosis-for-aortic-aneurysm-and-dissection-in-anzhendpanda-study-100303662",false,"NCT03233087","Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study","Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen","Inclusion Criteria:\n\nRetrospective\n\n* All patients who were referred to the surgical service for evaluation and management of aortic dissection were included.\n\nPerspective\n\n* Patients with initial suspicion of having AAD were perspectively enrolled.\n\nExclusion Criteria:\n\nRetrospective\n\n* Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken;\n* Patients with aortic trauma, pseudo aneurysm, history of heart failure, renal dysfunction, severe pulmonary diseases, or active cancer;\n* Patients who entered the hospital for checkups after surgery.\n\nPerspective\n\n* Patients in whom there is little or no suspicion of a life-threatening disease;\n* Patients with confirmed acute myocardial infarction,angina or pulmonary embolism\n* The symptoms were clearly not related to AD (e.g. pleurisy, pneumonia, acute abdominal diseases).","ALL","18 Years","80 Years",{"count":20,"type":21},1500,"ESTIMATED","OBSERVATIONAL","The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm\u002Faortic dissection.",[25,26],"Aortic Aneurysm","Aortic Dissection","RECRUITING","2024-06-26",{"date":30,"type":31},"2024-06-27","ACTUAL",{"date":33,"type":31},"2014-03-01",{"date":35,"type":21},"2028-12-31",{"name":37,"class":38},"Beijing Institute of Heart, Lung and Blood Vessel Diseases","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":39},"100533291","a-registry-study-of-biomarkers-in-heart-valve-disease-100533291","NCT06223906","A Registry Study of Biomarkers in Heart Valve Disease","BIOMS-HVD","Inclusion Criteria:\n\n* Patients clinically diagnosed with heart valve disease in Beijing Anzhen Hospital\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Failure to obtain medical records and ultrasound data\n* Refuse follow-up",true,"100 Years",{"count":50,"type":21},200000,"Valvular Heart Disease, impacting 2.5% of the population, is predominantly observed in the elderly and is on the rise. The primary conditions within this category are Aortic Stenosis and Mitral Regurgitation. These conditions are linked to considerable morbidity and mortality, presenting a formidable challenge in optimizing treatment strategies. Pathophysiology of Valvular Heart Disease remains poorly known. The aim of the present study is to identify biomarkers involved in this disease using multi-omics approaches",[53],"Cardiovascular Diseases","2024-01-24",{"date":56,"type":31},"2024-01-26",{"date":58,"type":31},"2016-01-01",{"date":60,"type":21},"2030-01-01",{"name":37,"class":38},{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":47,"sex":16,"minAge":17,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":39},"100314397","a-registry-study-on-biomarkers-of-takayasus-arteritis-arsbta-100314397","NCT03372980","A Registry Study on Biomarkers of Takayasu's Arteritis (ARSBTA)","A Registry Study on Biomarkers of Takayasu's Arteritis","Retrospective\n\nInclusion Criteria:\n\nSubjects who met the American College of Rheumatology 1990 classification criteria for Takayasu arteritis:\n\n1. Age of onset ≤40 years,\n2. Claudication of upper or lower extremities,\n3. Decreased pulsation of 1 or both brachial arteries,\n4. Difference of ≥ 10 mmHg in systolic blood pressure between arms,\n5. Bruit over subclavian arteries or aorta,\n6. \\*Arteriographic evidence showing a branch of the aorta stenosis or occlusion.\n\nMeeting more than 3 of 6 criteria suggests the diagnosis of Takayasu arteritis.\n\n\\*Angiography in this study was replaced by vascular magnetic resonance angiography(MRA)or computed tomography angiography(CTA).\n\nExclusion Criteria:\n\n1. Arteriographic lesions that could be entirely due to atherosclerosis,\n2. Suffer from other autoimmune diseases (eg, ANCA-associated vasculitis, systemic lupus erythematosus, etc.) besides Takayasu arteritis,\n3. Cogan's syndrome,\n4. Behcet's disease,\n5. Subjects with any serious acute or chronic infection,\n6. Giant cell arteritis (large vessel vasculitis and at least 50 years old) or other infectious forms of large vessel vasculitis.\n\nProspective\n\nInclusion Criteria:\n\nSubjects with initial suspicion of having Takayasu arteritis or patients with Takayasu arteritis need assessment of disease activity were prospectively enrolled.\n\nExclusion Criteria:\n\n1. Patients without image studies.\n2. Patients with confirmed other autoimmune diseases (eg, ANCA-associated vasculitis, systemic lupus erythematosus, etc.)","70 Years",{"count":71,"type":21},1000,"Takayasu arteritis is a chronic vasculitis mainly involving the aorta and its main branches such as the brachiocephalic, carotid, subclavian, vertebral, and renal arteries, as well as the coronary and pulmonary arteries. Inflammation causes segments of the vessels to become narrowed, blocked, or even stretched, possibly resulting in aneurysms. The disease is very rare but most commonly occurs in young Asian women. However, there is a considerable lack of understanding of the disease mechanism of Takayasu arteritis. Initially, the disease remains clinically silent (or remains undetected) until the patients present with vascular occlusion. Additionally, many individuals with Takayasu arteritis, however, have no apparent symptoms despite disease activity. Therefore, biomarkers for diagnosis and monitor disease activity in individuals with Takayasu arteritis are needed. In this study, the investigators therefore to use different methods to identify new biomarkers for diagnosing or monitoring the disease activity in individuals with Takayasu arteritis. These biomarkers may provide valuable insights into the underlying biochemical processes and aid the understanding of the pathophysiology of this disease.",[74],"Takayasu's Arteritis",[76],"Biomarkers","2022-04-11",{"date":79,"type":31},"2022-04-12",{"date":81,"type":31},"2016-01",{"date":83,"type":21},"2026-12",{"name":37,"class":38},""]