[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Beirut Arab University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":111},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100643946","peri-implant-soft-tissue-augmentation-using-microneedling-with-i-prf-vs-connective-tissue-graft-100643946",false,"NCT07667855","Peri-implant Soft Tissue Augmentation Using Microneedling With i-PRF vs. Connective Tissue Graft","Peri-implant Soft Tissue Augmentation Using Microneedling With i-PRF vs. Connective Tissue Graft: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Systemically healthy adults (Between 18 and 65) with one or more dental implants requiring second-stage surgery in the esthetic zone (Anteriors and Premolars).\n* Thin soft tissue phenotype: mucosal thickness or KTW \\\u003C2 mm buccally.\n* Stable osseointegrated implant, adequate restorative space, and healthy adjacent teeth.\n* Good oral hygiene (PI ≤10%), with peri-implant maintenance.\n* Signed consent + willingness for 1-year follow-up.\n\nExclusion Criteria:\n\n* Heavy smokers (≥10 cig\u002Fday); light smokers only if reduced.\n* Systemic\u002Fhealing issues: uncontrolled diabetes, immunocompromise, bleeding disorders, anticoagulants, steroids.\n* Pregnancy or breastfeeding.\n* Active infection (periodontal or peri-implant).\n* No residual keratinized mucosa on buccal side.\n* Previous graft\u002Faugmentation at the site or recent surgery (\\\u003C6 months).\n* Allergies to anesthetics\u002Fmaterials.\n* Non-compliance with instructions or follow-up.","ALL","18 Years","65 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled clinical trial aims to evaluate a minimally invasive technique for peri-implant soft tissue augmentation using microneedling combined with injectable platelet-rich fibrin (i-PRF) compared with the current gold-standard connective tissue graft (CTG). Patients with thin peri-implant soft tissue requiring implant second-stage surgery in the esthetic zone will be randomly assigned to receive either CTG harvested from the palate or a series of microneedling and i-PRF treatments. Clinical outcomes including mucosal thickness, keratinized tissue width, peri-implant health parameters, volumetric soft tissue changes, esthetic outcomes, and patient-reported measures of pain and satisfaction will be evaluated during follow-up. The study aims to determine whether microneedling with i-PRF can provide comparable soft tissue augmentation while reducing patient morbidity associated with connective tissue graft harvesting.",[27],"Thin Peri-implant Mucosal Phenotype",[29,30,31,32,33,34,35],"Microneedling","Injectable Platelet-Rich Fibrin","i-PRF","Peri-implant soft tissue augmentation","Implant Esthetics","Mucosal Thickness","Connective Tissue Graft","NOT_YET_RECRUITING","2026-06-19",{"date":39,"type":40},"2026-06-25","ACTUAL",{"date":42,"type":21},"2026-06-26",{"date":44,"type":21},"2027-03-26",{"name":46,"class":47},"Beirut Arab University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":48},"100612508","guided-bone-regeneration-in-lower-posterior-edentulous-arch-using-resorbable-or-non-resorbable-membrane-100612508","NCT07254494","Guided Bone Regeneration in Lower Posterior Edentulous Arch Using Resorbable or Non Resorbable Membrane.","Comparative Evaluation of Resorbable (Pericardium) Versus Non Resorbable (Polytetrafluoroethylene) Membrane for Horizontal Bone Augmentation of Posterior Atrophic Mandible","Inclusion Criteria:\n\n* Mandibular posterior atrophic alveolar ridge Required horizontal bone augmentation procedures prior to implant placement.\n* Alveolar bone height suitable for implant placement.\n* Free of any local or systemic condition that may contraindicate ridge expansion procedure\n* The capacity to understand and accept the conditions of the study.\n* Continuing participation over at least 1 year of follow-up.\n\nExclusion Criteria:\n\n* Heavy smokers (i.e., 2 or more packs of cigarettes per day);\n* Insufficient oral hygiene\n* Acute local or systemic infection\n* Patients with any systemic disease that may affect bone healing;\n* Pregnancy or the possibility of becoming pregnant during the study; and\n* Addiction to drugs or alcohol",true,"80 Years",{"count":59,"type":21},30,[24],"the purpose of this study is to compare the efficiency of non-resorbable membrane versus resorbable membrane in guided bone regeneration in atrophic posterior mandible.",[63,64],"Horizontal Alveolar Bone Defect","Guided Bone Regeneration",[66,67,68,69,70,71,72,73],"atrophic","horizontal bone loss","guided bone regeneration","pericardium membrane","PTFE membrane","resorbable membrane","non resorbable membrane","GBR","RECRUITING","2025-11-25",{"date":77,"type":40},"2025-11-28",{"date":79,"type":21},"2026-05",{"date":81,"type":21},"2026-12",{"name":46,"class":47},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":48},"100599591","early-phase-1-effect-of-cyanoacrylate-tissue-adhesive-versus-collagen-sponge-on-palatal-donor-site-healing-100599591","NCT07086482","Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing","Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing After Harvesting a Free Gingival Graft: a Randomized Controlled Clinical Trial","RCT","Inclusion Criteria:\n\n* Low-moderate anesthetic risk (ASA I-II)\n* No restriction on ethnicity or gender\n* Patients requiring FGG from the palate for periodontal plastic surgery\n* Clinically healthy gingiva after phase I therapy\n* Full-mouth plaque index grades 0 and 1\n* Bleeding scores \\\u003C15%\n\nExclusion Criteria:\n\n* Patients who smoke \\> 10 cigarettes\u002Fday\n* Patients with coagulation disorders\n* Systemic diseases\n* Patients on certain medications that may affect periodontal tissues\n* Pregnant and lactating patient\n* Patients with allergies to drugs that will be prescribed during the treatment phase\n* Pathological mental conditions (dementia, psychosis) and lack of cooperation\n* Excessive gag reflex",{"count":92,"type":21},22,[94],"EARLY_PHASE1","The goal of this clinical trial is to learn if the use of cyanoacrylate glue (PeriAcryl) is effective in healing of the palatal donor site in adults requiring a free gingival graft.\n\nThe main question\\[s\\] it aims to answer \\[is\u002Fare\\]:\n\nDoes PeriAcryl accelerate the palatal tissue healing compared with the use of collagen sponge? Does PeriAcryl usage leave the patients more satisfied?\n\nResearcher will compare the outcomes of participants treated with PeriAcryl to those treated with collagen sponge to see if PeriAcryl accelerated the healing process of palatal tissues and led to fewer postoperative complications.\n\nParticipants will:\n\n* be assigned to a study group using PeriAcryl or control group using Collagen sponge.\n* be followed-up to monitor healing and gather clinical information.",[97],"Palate; Wound",[99,100,101,102],"palatal donor area","Cyanoacrylate glue","wound healing","free gingival graft","2025-08-13",{"date":105,"type":40},"2025-08-17",{"date":107,"type":40},"2025-08-04",{"date":109,"type":21},"2026-04-20",{"name":46,"class":47},""]