[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Bernstein Clinical Research Center\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100578990","phase-4-lanadelumab-in-long-term-prophylaxis-of-acquired-angioedema-100578990",false,"NCT06818474","Lanadelumab in Long-term Prophylaxis of Acquired Angioedema","Inclusion Criteria:\n\n* A diagnosis of AAE with recurrent attacks without urticaria (decreased C1INH functional, quantitative levels, decreased C4 and decreased C1q levels, no family history of angioedema), presence of anti-C1INH antibody and\u002For paraproteinemia (e.g. monoclonal gammopathy of unknown significance)\n* historical attack rate of \\>= on attack per month prior to starting tranexamic acid (TAA)\n\nExclusion Criteria:\n\n* History of anaphylaxis or hypersensitivity to biologics\n* History of major systemic disease not well controlled in opinion of the PI\n* Women who are pregnant or breast feeding\n* Concurrent participation in other clinical trials\n* HAE Type 1 or 2 and normal complement HAE","ALL","18 Years",{"count":18,"type":19},5,"ESTIMATED","INTERVENTIONAL",[22],"PHASE4","use of lanadelumab in patients with acquired angioedema",[25],"Angioedema","RECRUITING","2025-02-24",{"date":29,"type":30},"2025-02-25","ACTUAL",{"date":32,"type":30},"2024-06-01",{"date":34,"type":19},"2027-12-01",{"name":36,"class":37},"Bernstein Clinical Research Center","OTHER",""]